Patents by Inventor Nathan Brent Sorensen

Nathan Brent Sorensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICROFLUIDIC PLATFORM FOR TARGET AND BIOMARKER DISCOVERY FOR NON-ALCOHOLIC FATTY LIVER DISEASE
    Publication number: 20210156846
    Abstract: A method for developing stratified medicine for nonalcoholic fatty liver disease (NAFLD includes obtaining a microphysiological system (MPS) comprising a liver tissue cytoarchitecture, adipose tissue, or both. The method includes inducing metabolic dysfunction representing NAFLD in the liver or adipose tissue of the MPS. The method includes generating, based on inducing the metabolic dysfunction, transcriptomics data for the MPS. The method includes applying a drug to the MPS using a dosing regimen. The method includes monitoring changes in the transcriptomics data based on applying the drug. The method includes generating a model relating the changes in the transcriptomics data to the dosing regimen of the drug.
    Type: Application
    Filed: November 25, 2020
    Publication date: May 27, 2021
    Inventors: Murat Cirit, Begum Alaybeyoglu, Nathan Brent Sorensen, John Wayne Rumsey