Patents by Inventor Nathan Brown

Nathan Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11564935
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: January 31, 2023
    Assignee: COMPASS Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Megan Croal, Hans Åke Eriksson, George Goldsmith, Molly Tabitha Hickey, Shaun Hurley, Ekaterina Malievskaia, Lindsey Marwood, Drummond E-Wen Joe McCulloch, Laurie Emma Medhurst, Nathan Poulsen, Aslihan Selimbeyoglu, Anaïs Soula, Amanda Tan Shuxiang, Manon Cecile Elisabeth Veraart, Tobias Patrick Whelan, Lars Christian Wilde, Stephen Wright
  • Publication number: 20230023092
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat depression, neurocognitive disorders, autism spectrum disorder, and/or attention-deficit/hyperactivity disorder.
    Type: Application
    Filed: April 17, 2020
    Publication date: January 26, 2023
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Ake ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anais SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • Publication number: 20230000883
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: April 17, 2020
    Publication date: January 5, 2023
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Ake ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anais SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • Publication number: 20220406412
    Abstract: A computer-implemented method of designing a molecule and determining a route to synthesise the molecule is provided. The method comprises: receiving one or more desired properties of the molecule; generating one or more candidate molecules using a first machine learning technique that uses the one or more desired properties of the molecule as an input; and for at least one candidate molecule, computing one or more routes to synthesise the candidate molecule using a second machine learning technique.
    Type: Application
    Filed: October 23, 2020
    Publication date: December 22, 2022
    Applicant: BENEVOLENTAI TECHNOLOGY LIMITED
    Inventors: Marwin Segler, Nathan Brown
  • Patent number: 11493293
    Abstract: A magazine for a firearm comprises a tubular magazine body defining a cavity for holding cartridges, a spring, and a follower biased by the spring for dispensing cartridges from the magazine. A spring base disposed on the body includes a cantilevered resiliently deformable spring arm supporting the spring in one embodiment. The base is held in place by the floor plate. Sliding the floor plate onto the magazine body engages an inclined ramp of the floor plate with spring arm which automatically moves the spring arm from an undeflected to deflected position. When the floor plate is fully coupled to the magazine tube such that the spring arm clears the ramp, the spring arm snaps back to the undeflected position and locks the floor plate in place on the tubular body via interlocked retention features without use of tools.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: November 8, 2022
    Inventors: Nathan Brown, Dwight Potter
  • Publication number: 20220339392
    Abstract: Described herein are devices, systems and methods for monitoring the use of a nebulized medication, such as can be administered using a nebulizer. These can be used for monitoring a patient undergoing treatment for COPD and improve compliance to the recommended therapy. Monitored parameters include flow, humidity and acceleration and provide data as to the quantity and quality of nebulizer use.
    Type: Application
    Filed: July 8, 2022
    Publication date: October 27, 2022
    Applicant: Sunovion Pharmaceuticals Inc.
    Inventors: Michael Segal, Nathan Arian Abel, Spencer Brown, Everett Crosland, Francisco Javier de Ana Arbeloa, Thomas Goodin, Joseph Gordon, Michael Metz, Daniel James Nelson, Jae Hong Park, Sean Scanlon, Janis Paulis Skujins, Jennet Toyjanova
  • Patent number: 11406786
    Abstract: Described herein are devices, systems and methods for monitoring the use of a nebulized medication, such as can be administered using a nebulizer. These can be used for monitoring a patient undergoing treatment for COPD and improve compliance to the recommended therapy. Monitored parameters include flow, humidity and acceleration and provide data as to the quantity and quality of nebulizer use.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: August 9, 2022
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Michael Segal, Nathan Abel, Spencer Brown, Everett Crosland, Francisco Javier de Ana Arbeloa, Thomas Goodin, Joseph Gordon, Michael Metz, Daniel Nelson, Jae Hong Park, Sean Scanlon, Janis Skujins, Jennet Toyjanova
  • Patent number: 11401180
    Abstract: Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: August 2, 2022
    Assignee: Battelle Memorial Institute
    Inventors: Lindy E. Dejarme, Kavitha Dasu, Russel R. Sirabian, Amy Dindal, Jeffrey Ellis, Amy Heintz, Dan Garbark, Nathan Bryant, John Tallarico, Joseph Casciano, Slawomir Winecki, David Holley, Joshua James, Keith Brown, Doug Hendry, Darwin Argumedo, Aaron Frank, Christopher Gordon Scheitlin, Michael M. Miller
  • Patent number: 11383340
    Abstract: The present invention provides a device (10) for the extraction of machining dust. The device (10) comprises a body (12) configured to be coupled to a section of a machining machine. The body (12) having a first opening (11) at a first end thereof and a second opening (13) at a second end thereof. The first end is opposite the second end, and the first opening (11) is configured to receive a tool holder therethrough and the second opening (13) configured to receive a cutting tool therethrough. The device also comprises a Venturi mechanism (14) connected to the body (12) and in fluid communication with said second opening (13). The Venturi mechanism (14) is configured to facilitate the suction of machining dust through the second opening (13) and through the Venturi mechanism (14).
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: July 12, 2022
    Inventors: Adam Brown, Rowan Easter-Robinson, Nathan Ray
  • Publication number: 20220047397
    Abstract: Deployable Euler Spiral Connectors (DESCs) are introduced as compliant deployable flexures that can span gaps between segments in a mechanism and then lay flat when under strain in a stowed position. This paper presents models of Euler spiral beams combined in series and parallel that can be used to design compact compliant mechanisms. Constraints on the flexure parameters of DESCs are also presented. Analytic models developed for the force-deflection behavior and stress were compared to finite element analysis and experimental data. A spinal implant and a linear ratcheting system are presented as illustrative applications of DESCs.
    Type: Application
    Filed: August 13, 2021
    Publication date: February 17, 2022
    Inventors: Larry L. Howell, Collin Ynchausti, Anton E. Bowden, Nathan Brown
  • Patent number: 11205522
    Abstract: An apparatus and method to remotely perform automated piping and piping attachment weld inspections. The apparatus has two spaced positioning arms that rotate out from one side of a frame structure and a kicker arm that rotates out from an opposite side of the frame structure at a location between the two positioning arms. The positioning arms and the kicker arm wedge the frame structure between an object to be scanned and an opposing structure. A scanning subassembly supported on the frame structure is configured to pivot and move in an appropriate direction and to pilot a transducer around the surface of the object to be scanned.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: December 21, 2021
    Assignee: Westinghouse Electric Company LLC
    Inventors: Kevin J. Foley, Nathan A. Brown, Charles R. Barrett
  • Publication number: 20210231396
    Abstract: A magazine for a firearm comprises a tubular magazine body defining a cavity for holding cartridges, a spring, and a follower biased by the spring for dispensing cartridges from the magazine. A spring base disposed on the body includes a cantilevered resiliently deformable spring arm supporting the spring in one embodiment. The base is held in place by the floor plate. Sliding the floor plate onto the magazine body engages an inclined ramp of the floor plate with spring arm which automatically moves the spring arm from an undeflected to deflected position. When the floor plate is fully coupled to the magazine tube such that the spring arm clears the ramp, the spring arm snaps back to the undeflected position and locks the floor plate in place on the tubular body via interlocked retention features without use of tools.
    Type: Application
    Filed: September 24, 2020
    Publication date: July 29, 2021
    Inventors: Nathan Brown, Dwight Potter
  • Publication number: 20210093451
    Abstract: Numerous delivery devices for delivery of a stented prosthesis, such as a stented prosthetic heart valve. Various delivery devices include a capsule that is advanced proximally to retain the stented prosthesis, which is secured over an inner shaft assembly of the delivery device. The delivery device further includes a bumper or bumper assembly to provide a smooth transition of the capsule over the stented prosthesis. In some alternate disclosed embodiments, the bumper further serves to connect various elements of the inner shaft assembly. Additional embodiments include a bumper assembly arranged and configured to longitudinally expand and contract to substantially fill any open space as the capsule is retracted from the stented prosthesis, which prevents kinking in the capsule. Additional embodiments include proximal and/or distal bumpers for temporarily covering and smoothing the ends of the stented prosthesis as part of a delivery device that does not include a capsule.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 1, 2021
    Applicant: Medtronic Vascular, Inc.
    Inventors: Don Tran, Martha Barajas-Torres, Marian Lally, Michael Gloss, Timothy Groen, Leonel Mendoza, Siyan Som, Michele Silver, Nathan Brown, Jill Mendelson
  • Publication number: 20210080211
    Abstract: A firearm with dual-acting safety mechanism includes a hammer, sear operable to hold the hammer in a cocked position, and trigger mechanism including a trigger and trigger bar which collectively operates to rotate the sear to release the hammer. The safety mechanism includes a safety mode selector or actuator cooperating with a secondary safety link. In one arrangement, linearly moving the selector actuates and rotates the safety link which simultaneously both blocks the hammer and displaces the trigger bar such that the sear can no longer be actuated via a trigger pull.
    Type: Application
    Filed: June 29, 2020
    Publication date: March 18, 2021
    Inventors: Jonathan Barrett, Nathan Brown, Darin Nebeker, Todd Wilkinson
  • Patent number: 10921075
    Abstract: A magazine for a firearm such as long guns comprises a housing defining a cavity for holding a double staggered stack of cartridges and spring-biased tiltable follower for dispensing the cartridges into the action of the firearm. Features include an accordion type flat spring specially configured to fold into a flat condition in which adjacent bends of the spring are arranged side-by-side to reduce the folded height of the spring. The follower includes bosses slideable in mating vertical housing slots to guide the follower upward/downward motion and allow front to rear tilting action. A coupling mechanism includes a plurality of interlocking mounting teeth forming a selectively interlocked arrangement for detachably assembling the floor plate to magazine housing. A resilient snap fit tab on the floor plate secures the coupling. The magazine is longitudinally elongated and configured to fit flushly with the underside of the firearm when mounted.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: February 16, 2021
    Assignee: STURM, RUGER & COMPANY, INC.
    Inventors: Nathan Brown, Matthew S. Willson, Dean M. Cousino, Maksim Sakalouski
  • Patent number: 10893938
    Abstract: Numerous delivery devices for delivery of a stented prosthesis, such as a stented prosthetic heart valve. Various delivery devices include a capsule that is advanced proximally to retain the stented prosthesis, which is secured over an inner shaft assembly of the delivery device. The delivery device further includes a bumper or bumper assembly to provide a smooth transition of the capsule over the stented prosthesis. In some alternate disclosed embodiments, the bumper further serves to connect various elements of the inner shaft assembly. Additional embodiments include a bumper assembly arranged and configured to longitudinally expand and contract to substantially fill any open space as the capsule is retracted from the stented prosthesis, which prevents kinking in the capsule. Additional embodiments include proximal and/or distal bumpers for temporarily covering and smoothing the ends of the stented prosthesis as part of a delivery device that does not include a capsule.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: January 19, 2021
    Assignee: Medtronic Vascular, Inc.
    Inventors: Don Tran, Martha Barajas-Torres, Marian Lally, Michael Gloss, Timothy Groen, Leonel Mendoza, Siyan Som, Michele Silver, Nathan Brown, Jill Mendelson
  • Publication number: 20200352714
    Abstract: Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a covering feature associated with the spindle for selectively covering at least a portion of a stented prosthetic heart valve tethered to the spindle in a delivery state. In some embodiments, the covering feature includes a tip mounted to the spindle. The tip can include an overhang region for selectively covering a portion of the stented prosthetic heart valve. In other embodiments, the tip can include a tip body and a compressible foam bumper. In yet other embodiments, the covering feature includes an outer sheath arranged to selectively cover the stented prosthetic heart valve. The outer sheath can be elastic and stretchable for recapturing a partially expanded prosthesis, for example by including one or more windows covered by a stretchable covering layer.
    Type: Application
    Filed: July 27, 2020
    Publication date: November 12, 2020
    Applicant: Medtronic Vascular, Inc.
    Inventors: Brendan Vaughan, Maeve Britton, Martha Barajas-Torres, Susheel Deshmukh, Leonel Mendoza, Siyan Som, Michele Silver, Don Tran, Nathan Brown, Jill Mendelson
  • Publication number: 20200350087
    Abstract: An apparatus and method to remotely perform automated piping and piping attachment weld inspections. The apparatus has two spaced positioning arms that rotate out from one side of a frame structure and a kicker arm that rotates out from an opposite side of the frame structure at a location between the two positioning arms. The positioning arms and the kicker arm wedge the frame structure between an object to be scanned and an opposing structure. A scanning subassembly supported on the frame structure is configured to pivot and move in an appropriate direction and to pilot a transducer around the surface of the object to be scanned.
    Type: Application
    Filed: February 3, 2020
    Publication date: November 5, 2020
    Applicant: Westinghouse Electric Company LLC
    Inventors: Kevin J. FOLEY, Nathan A. BROWN, Charles R. BARRETT
  • Patent number: 10788287
    Abstract: An adjustable stock for a firearm includes a longitudinally-extending chassis supporting a receiver, a butt pad assembly adjustable in longitudinal position for varying the length of pull, and a cheek rest. The cheek rest is adjustable in longitudinal and vertical positions. A triple-acting locking mechanism having locked and unlocked positions is operable to simultaneously lock the butt pad assembly in longitudinal position and the cheek rest in both longitudinal and vertical positions. The locking mechanism may be a cam lever assembly in non-limiting examples having a pivotable cam lever operable to simultaneously unlock or lock the butt pad assembly and cheek rest, thereby providing a single point of operation for making all the foregoing stock adjustments.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: September 29, 2020
    Inventors: Benjamin Keyes Parker, Jonathan Philip Mather, Jarod John Wendholt, Robert Earl Craig, Matthew Scott Willson, Nathan Brown
  • Patent number: 10758350
    Abstract: Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a covering feature associated with the spindle for selectively covering at least a portion of a stented prosthetic heart valve tethered to the spindle in a delivery state. In some embodiments, the covering feature includes a tip mounted to the spindle. The tip can include an overhang region for selectively covering a portion of the stented prosthetic heart valve. In other embodiments, the tip can include a tip body and a compressible foam bumper. In yet other embodiments, the covering feature includes an outer sheath arranged to selectively cover the stented prosthetic heart valve. The outer sheath can be elastic and stretchable for recapturing a partially expanded prosthesis, for example by including one or more windows covered by a stretchable covering layer.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: September 1, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventors: Brendan Vaughan, Maeve Britton, Martha Barajas-Torres, Susheel Deshmukh, Leonel Mendoza, Siyan Som, Michele Silver, Don Tran, Nathan Brown, Jill Mendelson