Patents by Inventor Nathan Chubb

Nathan Chubb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiparasitic terpene alkaloids
    Patent number: 7494992
    Abstract: The present invention relates to novel terpene alkaloids and their use as antiparasitic agents. The present invention also relates to an antiparasitic agent which comprises a terpene alkaloid compound of this invention as an effective ingredient in an antiparasitic formulation. More particularly, the present invention relates to derivatives of the terpene alkaloid (1S,2R,4aS,5R,8R,8aR)-2-(acetyloxy)-8a-hydroxy-3,8-dimethyl-5-(1-methylethenyl)-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl (2S,3aR,9bR)-6-chloro-9b-hydroxy-5-methyl-1,2,3,3a,5,9b-hexahydropyrrolo[2,3-c][2,1]benzoxazine-2-carboxylate. Pharmaceutical compositions comprising the same are also disclosed.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: February 24, 2009
    Assignee: Pfizer Inc.
    Inventors: Nathan A. Chubb, Douglas J. Critcher, James J. Eshelby, Graham Lunn, Andrew J. Rudge, Nigel D. Walshe, Paul H Wiedenau, David H. Williams
  • Antiparasitic terpene alkaloids
    Publication number: 20070185101
    Abstract: The present invention relates to novel terpene alkaloids and their use as antiparasitic agents. The present invention also relates to an antiparasitic agent which comprises a terpene alkaloid compound of this invention as an effective ingredient in an, antiparasitic formulation. More particularly, the present invention relates to derivatives of the terpene alkaloid (1S,2R,4aS,5R,8R,8aR)-2-(acetyloxy)-8a-hydroxy-3,8-dimethyl-5-(1-methylethenyl)-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl (2S,3aR,9bR)-6-chloro-9b-hydroxy-5-methyl-1,2,3,3a,5,9b-hexahydropyrrolo[2,3-c][2,1]benzoxazine-2-carboxylate. Pharmaceutical compositions comprising the same are also disclosed.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 9, 2007
    Inventors: Nathan Chubb, Douglas Critcher, James Eshelby, Graham Lunn, Andrew Rudge, Nigel Walshe, Paul Wiedenau, David Williams
  • Substituted arylpyrazoles
    Publication number: 20050148649
    Abstract: This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which there is at least one fluorine attached to the cyclopropyl ring, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
    Type: Application
    Filed: December 15, 2004
    Publication date: July 7, 2005
    Inventors: Denis Billen, Nathan Chubb, David Gethin, Kim Hall, Lee Roberts, Nigel Walshe