Patents by Inventor Nathan Crum

Nathan Crum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12252417
    Abstract: Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: March 18, 2025
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Nathan Crum, Joseph M. Jakubowski, Jerome W. Kosmeder, II, Eric May, Michael Otter, Taylor J. Shingler, Benjamin C. Stevens
  • Patent number: 12000765
    Abstract: A method and system for processing a sample in a fluid is provided. An assembly comprising a cap prefilled with a fixative solution, a valve, and a container for storing a tissue sample are provided. The valve is adapted to be situated between the cap and the container such that fluid can flow from the cap into the container when the assembly is upright, but the fluid cannot backflow from the container to the cap when the assembly is horizontal or inverted.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: June 4, 2024
    Assignee: Ventana Medic Systems, Inc.
    Inventors: Nathan Crum, Michael Otter
  • Patent number: 11970406
    Abstract: Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: April 30, 2024
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Nathan Crum, Joseph M. Jakubowski, Jerome W. Kosmeder, II, Eric May, Michael Otter, Taylor J. Shingler, Benjamin C. Stevens
  • Publication number: 20220306493
    Abstract: Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
    Type: Application
    Filed: June 9, 2022
    Publication date: September 29, 2022
    Inventors: Nathan Crum, Joseph M. Jakubowski, Jerome W. Kosmeder, II, Eric May, Michael Otter, Taylor J. Shingler, Benjamin C. Stevens
  • Publication number: 20220298028
    Abstract: Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
    Type: Application
    Filed: June 9, 2022
    Publication date: September 22, 2022
    Inventors: Nathan Crum, Joseph M. Jakubowski, Jerome W. Kosmeder, II, Eric May, Michael Otter, Taylor J. Shingler, Benjamin C. Stevens
  • Patent number: 11401177
    Abstract: Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: August 2, 2022
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Nathan Crum, Joseph M. Jakubowski, Jerome W. Kosmeder, II, Eric May, Michael Otter, Taylor J. Shingler, Benjamin C. Stevens
  • Publication number: 20220042885
    Abstract: The present disclosure is directed to specimen processing assemblies including (a) a lower plate (10), (b) an upper plate (30) complementary to the lower plate, and (c) a chamber formed therefrom. In some embodiments, the formed chamber is adapted to perform an unmasking operation, e.g. antigen retrieval and/or target retrieval. In some embodiments, the specimen processing assemblies are configured to maintain a specimen-bearing substrate (15) horizontal during all processing steps. The present disclosure is also directed to systems including one or more independently operable specimen processing assemblies.
    Type: Application
    Filed: October 14, 2021
    Publication date: February 10, 2022
    Inventors: Heidi Barnett, Vanessa J. Bennett, Patrick Brown, Nathan Crum, Evan T. Graves, Timothy J. Keller, Brian H. Kram, Daniel R. Kurycki, Alastair Laing, Matthew D. Mette, Michael Otter, James E. PHILLIPS-PORTILLO, Samuel Psota, Christian Roessler, Kenneth S. Weir, John D. Willems, JR.
  • Publication number: 20210394172
    Abstract: A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° C. The pre-soaking process can, for example, be performed during sample transport or during extended periods of storage, such as over a weekend.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 23, 2021
    Inventors: Nathan Crum, Timothy Keller, Alastair Laing, Michael Otter, Vinnie Petre, Elizabeth Pigman, Taylor Shingler, Stacey Stanislaw, Benjamin Stevens
  • Patent number: 11071978
    Abstract: A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° C. The pre-soaking process can, for example, be performed during sample transport or during extended periods of storage, such as over a weekend.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: July 27, 2021
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Nathan Crum, Timothy Keller, Alastair Laing, Michael Otter, Vinnie Petre, Elizabeth Pigman, Taylor Shingler, Stacey Stanislaw, Benjamin Stevens
  • Publication number: 20210190650
    Abstract: A method and system for processing a sample in a fluid is provided. An assembly comprising a cap prefilled with a fixative solution, a valve, and a container for storing a tissue sample are provided. The valve is adapted to be situated between the cap and the container such that fluid can flow from the cap into the container when the assembly is upright, but the fluid cannot backflow from the container to the cap when the assembly is horizontal or inverted.
    Type: Application
    Filed: March 9, 2021
    Publication date: June 24, 2021
    Inventors: Nathan Crum, Michael Otter
  • Patent number: 10983034
    Abstract: A method and system for processing a sample in a fluid is provided. An assembly comprising a cap prefilled with a fixative solution, a valve, and a container for storing a tissue sample are provided. The valve is adapted to be situated between the cap and the container such that fluid can flow from the cap into the container when the assembly is upright, but the fluid cannot backflow from the container to the cap when the assembly is horizontal or inverted.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: April 20, 2021
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Nathan Crum, Michael Otter
  • Publication number: 20190300392
    Abstract: Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
    Type: Application
    Filed: June 14, 2019
    Publication date: October 3, 2019
    Inventors: Nathan Crum, Joseph M. Jakubowski, Jerome W. Kosmeder, II, Eric May, Michael Otter, Taylor J. Shingler, Benjamin C. Stevens
  • Publication number: 20180128718
    Abstract: A method and system for processing a sample in a fluid is provided. An assembly comprising a cap prefilled with a fixative solution, a valve, and a container for storing a tissue sample are provided. The valve is adapted to be situated between the cap and the container such that fluid can flow from the cap into the container when the assembly is upright, but the fluid cannot backflow from the container to the cap when the assembly is horizontal or inverted.
    Type: Application
    Filed: August 18, 2017
    Publication date: May 10, 2018
    Inventors: Nathan Crum, Michael Otter
  • Publication number: 20170320054
    Abstract: A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° C. The pre-soaking process can, for example, be performed during sample transport or during extended periods of storage, such as over a weekend.
    Type: Application
    Filed: July 25, 2017
    Publication date: November 9, 2017
    Inventors: Nathan Crum, Timothy Keller, Alastair Laing, Michael Otter, Vinnie Petre, Elizabeth Pigman, Taylor Shingler, Stacey Stanislaw, Benjamin Stevens