Patents by Inventor Nathan D. Trinklein

Nathan D. Trinklein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HEAVY CHAIN ANTIBODIES BINDING TO CD22
    Publication number: 20240117046
    Abstract: Anti-CD22 heavy chain antibodies (e.g., UniAbs™) are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B cell disorders that are characterized by the expression of CD22.
    Type: Application
    Filed: December 7, 2023
    Publication date: April 11, 2024
    Inventors: Shelley Force Aldred, Wim van Schooten, Heather Anne N. Ogana, Laura Marie Davison, Katherine Harris, Udaya Rangaswamy, Nathan D. Trinklein
  • Heavy chain antibodies binding to CD22
    Patent number: 11873336
    Abstract: Anti-CD22 heavy chain antibodies (e.g., UniAbs™) are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B cell disorders that are characterized by the expression of CD22.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: January 16, 2024
    Assignee: TENEOBIO, INC.
    Inventors: Shelley Force Aldred, Wim van Schooten, Heather Anne N. Ogana, Laura Marie Davison, Katherine Harris, Udaya Rangaswamy, Nathan D. Trinklein
  • HEAVY CHAIN ANTIBODIES BINDING TO CD22
    Publication number: 20210095022
    Abstract: Anti-CD22 heavy chain antibodies (e.g., UniAbs™) are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B cell disorders that are characterized by the expression of CD22.
    Type: Application
    Filed: December 21, 2018
    Publication date: April 1, 2021
    Inventors: Shelley Force Aldred, Win van Schooten, Healther N. Ogana, Laura Mari Daviison, Kathrine Harris, Udaya Rangaswamy, Nathan D. Trinklein
  • Transcription biomarkers of biological responses and methods of use
    Patent number: 10663455
    Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: May 26, 2020
    Assignee: ACTIVE MOTIF, INC.
    Inventors: Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
  • TRANSCRIPTION BIOMARKERS OF BIOLOGICAL RESPONSES AND METHODS OF USE
    Publication number: 20170191987
    Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
    Type: Application
    Filed: March 13, 2017
    Publication date: July 6, 2017
    Inventors: Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
  • Transcription biomarkers of biological responses and methods of use
    Patent number: 9663823
    Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
    Type: Grant
    Filed: July 13, 2014
    Date of Patent: May 30, 2017
    Assignee: SWITCHGEAR GENOMICS, INC.
    Inventors: Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
  • Modified renilla luciferase nucleic acids and methods of use
    Patent number: 9006405
    Abstract: This invention provides modified nucleotide sequences encoding luciferase that have greater expression than wild type luciferase.
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: April 14, 2015
    Assignee: SwitchGear Genomics, Inc.
    Inventors: Nathan D. Trinklein, Shelley Force Aldred
  • TRANSCRIPTION BIOMARKERS OF BIOLOGICAL RESPONSES AND METHODS OF USE
    Publication number: 20140364336
    Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
    Type: Application
    Filed: July 13, 2014
    Publication date: December 11, 2014
    Applicant: SWITCHGEAR GENOMICS, INC.
    Inventors: Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
  • Transcription biomarkers of biological responses and methods
    Patent number: 8815779
    Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
    Type: Grant
    Filed: September 16, 2009
    Date of Patent: August 26, 2014
    Assignee: SwitchGear Genomics, Inc.
    Inventors: Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
  • Modified renilla luciferase nucleic acids and methods of use
    Publication number: 20120035077
    Abstract: This invention provides modified nucleotide sequences encoding luciferase that have greater expression than wild type luciferase.
    Type: Application
    Filed: May 27, 2011
    Publication date: February 9, 2012
    Applicant: SwitchGear Genomics
    Inventors: Nathan D. Trinklein, Shelley Force Aldred
  • Transcription biomarkers of biological responses and methods
    Publication number: 20110065100
    Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
    Type: Application
    Filed: September 16, 2009
    Publication date: March 17, 2011
    Applicant: SwitchGear Genomics, Inc., a Delaware Corporation
    Inventors: Shelley Force Aldred, Michael Rose, Patrick Collins, Nathan D. Trinklein