Patents by Inventor Nathan E. Goldfarb

Nathan E. Goldfarb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition and method for HIP1-targeting inhibitor compounds
    Patent number: 12605456
    Abstract: Provided herein is an inhibitor compound targeting Hip1, with the inhibitor compound comprising a tripeptide targeting sequence that directs the compound to the active site of Hip1 and a C-terminal electrophilic warhead conjugated to the targeting sequence, the warhead configured to inactive the enzyme.
    Type: Grant
    Filed: May 28, 2022
    Date of Patent: April 21, 2026
    Assignee: Utah Valley University
    Inventors: Nathan E. Goldfarb, Andrew Abell, Nicholas Schumann, Borja Lopez Perez
  • COMPOSITIONS AND METHODS FOR HIP1-TARGETING INHIBITOR COMPOUNDS
    Publication number: 20250237649
    Abstract: Provided herein are inhibitor compounds targeting Hip1, with the inhibitor compounds comprising a tripeptide targeting sequence that directs the compound to the active site of Hip1 and a C-terminal electrophilic warhead conjugated to the targeting sequence, the warhead configured to inactive the enzyme. Further provided herein are embodiments of a treatment method and embodiments of an assay including embodiments of a rapid, point-of-care lateral flow assay (LFA).
    Type: Application
    Filed: April 11, 2025
    Publication date: July 24, 2025
    Inventors: Nathan E. Goldfarb, Andrew D. Abell, Nicholas C. Schumann, Borja Lopez Perez
  • COMPOSITION AND METHOD FOR HIP1-TARGETING INHIBITOR COMPOUNDS
    Publication number: 20230001000
    Abstract: Provided herein is an inhibitor compound targeting Hip1, with the inhibitor compound comprising a tripeptide targeting sequence that directs the compound to the active site of Hip1 and a C-terminal electrophilic warhead conjugated to the targeting sequence, the warhead configured to inactive the enzyme.
    Type: Application
    Filed: May 28, 2022
    Publication date: January 5, 2023
    Inventors: Nathan E. Goldfarb, Andrew Abell, Nicholas Schumann, Borja Lopez Perez