Patents by Inventor Nathan Geething

Nathan Geething has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Growth hormone polypeptides and methods of making and using same
    Patent number: 9168312
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of growth hormone-related diseases, disorders, and conditions.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: October 27, 2015
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-wei Wang, Nathan Geething, Jeffrey L. Cleland, Benjamin Spink
  • GLUCOSE-REGULATING POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
    Publication number: 20150274800
    Abstract: The present invention relates to compositions comprising glucose regulating peptides linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of glucose regulating peptide-related diseases, disorders, and conditions.
    Type: Application
    Filed: December 5, 2014
    Publication date: October 1, 2015
    Inventors: Volker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-wei Wang, Nathan Geething, Jeffrey L. Cleland
  • FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20150158929
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: July 11, 2012
    Publication date: June 11, 2015
    Applicants: AMUNIX OPERATING INC., BIOGEN IDEC MA INC.
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, Sheng Ding, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, John Kulman, Tongyao Liu, Garabet G. Toby, Haiyan Jiang, Robert Peters, Deping Wang, Baisong Mei
  • Glucose-regulating polypeptides and methods of making and using same
    Patent number: 8957021
    Abstract: The present invention relates to compositions comprising glucose regulating peptides linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of glucose regulating peptide-related diseases, disorders, and conditions.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: February 17, 2015
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-wei Wang, Nathan Geething, Jeffrey L. Cleland
  • FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20150038421
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: June 27, 2014
    Publication date: February 5, 2015
    Inventors: Volker SCHELLENBERGER, Pei-Yun Chang, Fatbardha Varfaj, John Kulman, Tongyao Liu, Garabet G. Toby, Haiyan Jiang, Robert Peters, Deping Wang, Baisong Mei, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Nathan Geething
  • GROWTH HORMONE POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
    Publication number: 20140371136
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of growth hormone-related diseases, disorders, and conditions.
    Type: Application
    Filed: January 10, 2014
    Publication date: December 18, 2014
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-wei Wang, Nathan Geething, Jeffrey L. Cleland
  • EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
    Publication number: 20140301974
    Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
    Type: Application
    Filed: January 30, 2014
    Publication date: October 9, 2014
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, Wayne To, Jeffrey L. Cleland
  • Coagulation factor VII compositions and methods of making and using same
    Patent number: 8716448
    Abstract: The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: May 6, 2014
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem Stemmer, Chia-wei Wang, Benjamin Spink, Nathan Geething, Wayne To
  • Growth hormone polypeptides and methods of making and using same
    Patent number: 8703717
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of growth hormone-related diseases, disorders, and conditions.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: April 22, 2014
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Willem P. Stemmer, Nathan Geething, Jeffrey L. Cleland
  • Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
    Patent number: 8680050
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in administration to animals.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: March 25, 2014
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-Wei Wang, Nathan Geething, Jeffrey L. Cleland
  • BINDING FUSION PROTEINS, BINDING FUSION PROTEIN-DRUG CONJUGATES, XTEN-DRUG CONJUGATES AND METHODS OF MAKING AND USING SAME
    Publication number: 20130165389
    Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.
    Type: Application
    Filed: September 28, 2012
    Publication date: June 27, 2013
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Susan E. Alters, Nathan Geething
  • Factor VIII Compositions and Methods of Making and Using Same
    Publication number: 20130017997
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: February 2, 2012
    Publication date: January 17, 2013
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, John Kulman, Tongyao Liu, Garabet G. Toby, Haiyan Jiang, Robert Peters, Deping Wang, Baisong Mei, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Nathan Geething
  • FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20120178691
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: March 16, 2012
    Publication date: July 12, 2012
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Nathan Geething
  • GROWTH HORMONE POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
    Publication number: 20110172146
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in administration to animals.
    Type: Application
    Filed: August 2, 2010
    Publication date: July 14, 2011
    Applicant: Amunix Operating, Inc.
    Inventors: VOLKER SCHELLENBERGER, Joshua Silverman, Willem P. Stemmer, Chia-Wei Wang, Nathan Geething
  • GROWTH HORMONE POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
    Publication number: 20110077199
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of growth hormone-related diseases, disorders, and conditions.
    Type: Application
    Filed: June 8, 2010
    Publication date: March 31, 2011
    Applicant: Amunix, Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Willem P. Stemmer, Nathan Geething
  • Coagulation factor VII compositions and methods of making and using same
    Publication number: 20110046061
    Abstract: The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
    Type: Application
    Filed: August 2, 2010
    Publication date: February 24, 2011
    Applicant: Amunix Operating, Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem Stemmer, Chia-wei Wang, Benjamin Spink, Nathan Geething, Wayne To
  • Coagulation factor IX compositions and methods of making and using same
    Publication number: 20110046060
    Abstract: The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
    Type: Application
    Filed: August 2, 2010
    Publication date: February 24, 2011
    Applicant: Amunix Operating, Inc.,
    Inventors: Volker Schellenberger, Joshua Silverman, Willem Stemmer, Chia-wei Wang, Benjamin Spink, Nathan Geething, Wayne To
  • GLUCOSE-REGULATING POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
    Publication number: 20100323956
    Abstract: The present invention relates to compositions comprising glucose regulating peptides linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of glucose regulating peptide-related diseases, disorders, and conditions.
    Type: Application
    Filed: June 8, 2010
    Publication date: December 23, 2010
    Applicant: AMUNIX, INC.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Willem P. Stemmer, Nathan Geething