Abstract: Provided herein are compositions and methods for the treatment of cancers using modified TILs, wherein the modified TILs include one or more immunomodulatory agents (e.g., cytokines) associated with their cell surface. The immunomodulatory agents associated with the TILs provide a localized immunostimulatory effect that can advantageously enhance TIL survival, proliferation and/or anti-tumor activity in a patient recipient. As such, the compositions and methods disclosed herein provide effective cancer therapies.

Abstract: An improvement in a regenerator which incorporates an external plenum on the exterior of the regenerator apparatus for receiving and collecting the flue gases separated from regenerated catalyst by a plurality of cyclone separators or other separating apparatus is disclosed. The external plenum communicates by means of stand pipes through the wall of the regenerator. This supports the cyclone separators or other separating means mechanically and avoids certain thermal stresses which would otherwise occur in the plenum if it were placed on the interior of the regeneration chamber.