Patents by Inventor Nathan Graeme DOLLOFF

Nathan Graeme DOLLOFF has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating secondary bone tumors with antibodies against PDGFR alpha
    Patent number: 8425911
    Abstract: The invention provides methods of treating bone cancer, particularly metastatic bone cancer, by administering a PDGFR alpha antagonist. The invention further provides methods of treating a mammal with a neoplastic disease using the antibodies alone or in combination with other agents.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: April 23, 2013
    Assignees: ImClone LLC, Philadelphia Health and Education Corporation
    Inventors: Nick Loizos, Alessandro Fatatis, Nathan Graeme Dolloff
  • METHODS OF TREATING SECONDARY BONE TUMORS WITH ANTIBODIES AGAINST PDGFR ALPHA
    Publication number: 20120034244
    Abstract: The invention provides methods of treating bone cancer, particularly metastatic bone cancer, by administering an IGF-IR antagonist and/or a PDGFR? antagonist. The invention also provides antibodies that bind to human PDGFR? and neutralize activation of the receptor. The invention further provides a methods for neutralizing activation of PDGFR?, and a methods of treating a mammal with a neoplastic disease using the antibodie alone or in combination with other agents.
    Type: Application
    Filed: October 19, 2011
    Publication date: February 9, 2012
    Applicants: PHILADELPHIA HEALTH AND EDUCATION CORPORATION D/B/A DREXEL UNIVERSITY COLLEGE, IMCLONE LLC
    Inventors: Nick LOIZOS, Alessandro FATATIS, Nathan Graeme DOLLOFF