Abstract: The digital amplification methods and kits provide the ability to estimate the fetal fraction of cell-free DNA (cfDNA) in a maternal sample, e.g., plasma or serum, by analysis of target sites that are differentially methylated in fetal and maternal cfDNA.

Abstract: The present disclosure relates to a component for a delivery system. The component comprises a body of material, a plurality of aerosol-modifying agent capsules in the body of material, and a plurality of particles in the body of material. The aerosol-modifying agent capsules and/or particles are interspersed within the body of material. The particles are configured such that, in use, the particles promote breaking of the aerosol-modifying agent capsules upon the application of an external force to the aerosol provision system component by a user.

Abstract: Systems and methods for diagnosing and treating a neurodegenerative disorder in a subject can be used for the diagnosis of Mild Cognitive Impairment, Early Mild Cognitive Impairment, Late Mild Cognitive Impairment, Parkinson's Disease, Dementia or Alzheimer's Disease in a subject, and for the treatment of a subject diagnosed with such neurodegenerative diseases.

Abstract: Overloaded typing apparatuses, and related devices, systems, and methods are disclosed. In one embodiment, a typing apparatus is provided. The typing apparatus comprises a plurality of overloaded keys in a key layout. The plurality of overloaded keys comprises at least three injectively overloaded keys disposed in a first row of keys. At least one first injectively overloaded key among the at least three injectively overloaded keys is injectively overloaded with a first at least three characters assigned to a first finger in a represented non-overloaded keyboard. The plurality of overloaded keys also comprises at least one second injectively overloaded key disposed outside the first row of keys. The at least one second injectively overloaded key is injectively overloaded with a second at least three characters assigned to the first finger in the represented non-overloaded keyboard. Other embodiments and related methods are also disclosed.

Abstract: Overloaded typing apparatuses, and related devices, systems, and methods are disclosed. In one embodiment, a typing apparatus is provided. The typing apparatus comprises a plurality of overloaded keys in a key layout. The plurality of overloaded keys comprises at least three injectively overloaded keys disposed in a first row of keys. At least one first injectively overloaded key among the at least three injectively overloaded keys is injectively overloaded with a first at least three characters assigned to a first finger in a represented non-overloaded keyboard. The plurality of overloaded keys also comprises at least one second injectively overloaded key disposed outside the first row of keys. The at least one second injectively overloaded key is injectively overloaded with a second at least three characters assigned to the first finger in the represented non-overloaded keyboard. Other embodiments and related methods are also disclosed.

Abstract: Fabric softening compositions comprising front-end stability agents exhibiting desirable viscosity profiles even when they contain polymeric delivery enhancing agents. Compositions comprising softening actives based on hardened tallow fatty acids are pumpable, pourable liquids and provide “low dose” fabric softeners for consumer use.

Abstract: Fabric softening compositions comprising front-end stability agents exhibiting desirable viscosity profiles even when they contain polymeric delivery enhancing agents. Compositions comprising softening actives based on hardened tallow fatty acids are pumpable, pourable liquids and provide “low dose” fabric softeners for consumer use.

Abstract: Overloaded typing apparatuses, and related devices, systems, and methods are disclosed. In one embodiment, a typing apparatus is provided. The typing apparatus comprises a plurality of overloaded keys in a key layout. The plurality of overloaded keys comprises at least three injectively overloaded keys disposed in a first row of keys. At least one first injectively overloaded key among the at least three injectively overloaded keys is injectively overloaded with a first at least three characters assigned to a first finger in a represented non-overloaded keyboard. The plurality of overloaded keys also comprises at least one second injectively overloaded key disposed outside the first row of keys. The at least one second injectively overloaded key is injectively overloaded with a second at least three characters assigned to the first finger in the represented non-overloaded keyboard. Other embodiments and related methods are also disclosed.