Patents by Inventor Nathan Higginson-Scott

Nathan Higginson-Scott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted Immunotolerance
    Publication number: 20220002409
    Abstract: Methods and compounds for conferring site-specific or local immune privilege.
    Type: Application
    Filed: February 10, 2021
    Publication date: January 6, 2022
    Inventors: Joanne L. Viney, Nathan Higginson-Scott, Micah Benson, Alan Crane
  • TARGETED IMMUNOTOLERANCE
    Publication number: 20210277085
    Abstract: Methods and compounds for conferring site-specific or local immune privilege.
    Type: Application
    Filed: November 20, 2018
    Publication date: September 9, 2021
    Applicant: Pandion Therapeutics, Inc.
    Inventors: Nathan HIGGINSON-SCOTT, Joanne L. VINEY, Jyothsna VISWESWARAIAH, Erik Robert SAMPSON, Kevin Lewis OTIPOBY
  • TISSUE TARGETED IMMUNOTOLERANCE WITH A CD39 EFFECTOR
    Publication number: 20210269496
    Abstract: Methods and compounds for conferring site-specific or local immune privilege, such as to the skin.
    Type: Application
    Filed: February 18, 2021
    Publication date: September 2, 2021
    Inventors: Daniel Rios, Purvi Mande, Joanne L. Viney, Nathan Higginson-Scott, Kevin Lewis Otipoby, Susmita Borthakur, Salvatore Alioto, Lindsay J. Edwards
  • IL-2 muteins and uses thereof
    Patent number: 11091527
    Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: August 17, 2021
    Assignee: PANDION OPERATIONS, INC.
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Jyothsna Visweswaraiah, Erik Robert Sampson, Kevin Lewis Otipoby
  • IL-2 muteins and uses thereof
    Patent number: 11091526
    Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: August 17, 2021
    Assignee: PANDION OPERATIONS, INC.
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Jyothsna Visweswaraiah, Erik Robert Sampson, Kevin Lewis Otipoby
  • RECOMBINANT ROBO2 PROTEINS, COMPOSITIONS, METHODS AND USES THEREOF
    Publication number: 20210214414
    Abstract: The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.
    Type: Application
    Filed: December 17, 2020
    Publication date: July 15, 2021
    Inventors: Stephen Berasi, Janet Elizabeth Buhlmann, Nathan Higginson-Scott, Michael Shamashkin, Matthew Russo, Stefano V. Gulla, Zong Sean Juo, Sreekumar R. Kodangattil, Weining Lu, Xueping Fan, David J. Salant
  • TARGETED IMMUNOTOLERANCE WITH A PD-1 AGONIST
    Publication number: 20210206856
    Abstract: Methods and polypeptides for conferring site-specific or local immune privilege.
    Type: Application
    Filed: August 19, 2020
    Publication date: July 8, 2021
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Kevin Lewis Otipoby, Salvatore Alioto, Lindsay J. Edwards, Jacob Glanville, David Maurer, Sarah Ives, Sawsan Youssef, Devanshi Shanghavi, Lauren Schwimmer
  • Targeted Immunotolerance
    Publication number: 20210094996
    Abstract: Methods and compounds for conferring site-specific or local immune privilege.
    Type: Application
    Filed: April 24, 2020
    Publication date: April 1, 2021
    Inventors: Joanne L. Viney, Nathan Higginson-Scott
  • Targeted immunotolerance
    Patent number: 10961310
    Abstract: Methods and compounds for conferring site-specific or local immune privilege.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: March 30, 2021
    Assignee: PANDION OPERATIONS, INC.
    Inventors: Joanne L. Viney, Nathan Higginson-Scott, Micah Benson, Alan Crane
  • IL-2 muteins and uses thereof
    Patent number: 10946068
    Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: March 16, 2021
    Assignee: PANDION OPERATIONS, INC.
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Jyothsna Visweswaraiah, Erik Robert Sampson, Kevin Lewis Otipoby
  • Recombinant ROBO2 proteins, compositions, methods and uses thereof
    Patent number: 10906955
    Abstract: The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: February 2, 2021
    Assignees: Pfizer Inc., Boston Medical Center Corporation
    Inventors: Stephen Berasi, Janet Elizabeth Buhlmann, Nathan Higginson-Scott, Michael Shamashkin, Matthew Russo, Stefano V. Gulla, Zong Sean Juo, Sreekumar R. Kodangattil, Weining Lu, Xueping Fan, David J. Salant
  • MAdCAM TARGETED IMMUNOTOLERANCE
    Publication number: 20200392228
    Abstract: Methods and compounds for conferring site-specific or local immune privilege, such as targeting to a cell expressing MAdCAM.
    Type: Application
    Filed: May 20, 2020
    Publication date: December 17, 2020
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Kevin Lewis Otipoby, Jyothsna Visweswaraiah, Salvatore Alioto, Lindsay J. Edwards, Erik Sampson, Jacob Glanville, David Maurer, Sarah Ives, Christina Pettus, Lauren Schwimmer
  • IL-2 MUTEINS AND USES THEREOF
    Publication number: 20200325202
    Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
    Type: Application
    Filed: November 25, 2019
    Publication date: October 15, 2020
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Jyothsna Visweswaraiah, Erik Robert Sampson, Kevin Lewis Otipoby
  • IL-2 MUTEINS AND USES THEREOF
    Publication number: 20200325201
    Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
    Type: Application
    Filed: November 25, 2019
    Publication date: October 15, 2020
    Inventors: Nathan Higginson-Scott, Joanne L. Viney, Jyothsna Visweswaraiah, Erik Robert Sampson, Kevin Lewis Otipoby
  • Targeted immunotolerance
    Patent number: 10676516
    Abstract: Methods and compounds for conferring site-specific or local immune privilege.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: June 9, 2020
    Assignee: PANDION THERAPEUTICS, INC.
    Inventors: Joanne L. Viney, Nathan Higginson-Scott
  • ANTI-ROBO2 ANTIBODIES, COMPOSITIONS, METHODS AND USES THEREOF
    Publication number: 20200157212
    Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to ROBO2, as well as uses, and methods thereof.
    Type: Application
    Filed: June 8, 2018
    Publication date: May 21, 2020
    Inventors: Stephen Berasi, Janet Elizabeth Buhlmann, Eric M. Bennett, Nathan Higginson-Scott, Huilan Gao, Zong Sean Juo, Stefano V. Gulla, Christine Huard, Sreekumar R. Kodangattil, Jian Li, Weining Lu, Xueping Fan, David J. Salant
  • Methods for profiling extracellular vesicles from combinatorial phage display libraries
    Patent number: 10633649
    Abstract: A method for profiling extracellular vesicles (EV) is provided.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: April 28, 2020
    Assignee: Verily Life Sciences LLC
    Inventors: Alberto Clemente Vitari, Joshua Simon Klein, Nathan Higginson-Scott, Nathan Pierce
  • BISPECIFIC ANTIBODIES
    Publication number: 20200123260
    Abstract: The present invention relates to engineered heteromultimeric proteins, and more specifically, to methods for producing and purifying heterodimeric proteins, such as bispecific antibodies and. Methods for producing and purifying such engineered heterodimeric proteins and their use in diagnostics and therapeutics are also provided. The present invention also relates to a humanized antibody that specifically binds human TrkB and methods for producing and using the antibody to, inter alia, treat a hearing loss disorder.
    Type: Application
    Filed: June 26, 2019
    Publication date: April 23, 2020
    Inventors: Eric M. Bennett, Nathan Higginson-Scott, Lioudmila Tchistiakova, Kimberly A. Marquette, Janet E. Paulsen, Ruth E. Gimeno
  • IL-2 MUTEINS AND USES THEREOF
    Publication number: 20190321446
    Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
    Type: Application
    Filed: November 28, 2018
    Publication date: October 24, 2019
    Inventors: Nathan HIGGINSON-SCOTT, Joanne L. VINEY, Jyothsna VISWESWARAIAH, Erik Robert SAMPSON, Kevin Lewis OTIPOBY
  • Bispecific antibodies
    Patent number: 10392438
    Abstract: The present invention relates to engineered heteromultimeric proteins, and more specifically, to methods for producing and purifying heterodimeric proteins, such as bispecific antibodies and. Methods for producing and purifying such engineered heterodimeric proteins and their use in diagnostics and therapeutics are also provided. The present invention also relates to a humanized antibody that specifically binds human TrkB and methods for producing and using the antibody to, inter alia, treat a hearing loss disorder.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: August 27, 2019
    Assignee: PFIZER INC.
    Inventors: Eric M. Bennett, Nathan Higginson-Scott, Lioudmila Tchistiakova, Kimberly A. Marquette, Janet E. Paulsen, Ruth E. Gimeno