Abstract: A liquid crystal display (LCD) apparatus that has increased contrast in displayed images, from the viewing side includes; a first external linear polarizer layer having a transmission axis aligned along in a first direction, a color filter substrate layer. A patterned color filter layer including individual color filters, a guest-host in-cell polarizer alignment layer an in-cell guest-host polarizer layer having a transmission axis aligned along the first direction, a first liquid crystal (LC) alignment layer, an LC layer, a second LC alignment layer, a first electrode layer, a thin film transistor (TFT) substrate layer, a second external polarizer layer having a transmission axis aligned along a second direction perpendicular to the first direction, and a backlight unit configured for illuminating the LCD apparatus.

Abstract: A method of fabricating a reactive mesogen (RM) guest-host polarizer is disclosed. The method includes forming an RM guest-host polarizer material on a substrate that promotes a substantially uniform planar alignment configuration of the RM guest-host molecules, forming a temporary layer on the RM guest-host polarizer material to align RM guest-host molecules of the RM guest-host polarizer material in the substantially uniform planar alignment configuration, performing polymerization of the RM guest-host polarizer material, and removing the temporary layer from the RM guest-host polarizer. The temporary layer includes at least one of a temporary fluid layer, a temporary particulate layer, a temporary gaseous layer, a temporary vacuum layer, and a temporary alignment substrate layer.

Abstract: Methods and systems directed to monitoring for the presence or progression of amyloid diseases via detection of amyloid fibrils in a sample from an individual are disclosed. An individual, or sample from an individual, is treated with a reagent including a fluorescent protein. The fluorescent protein in the reagent binds to amyloid fibrils present in the sample. Detecting a signal from fluorescent protein bound to the treated sample indicates the presence of amyloid fibrils in the sample and possible diagnosis of an amyloid disease. The presence and progression of an amyloid disease is monitored by quantifying signal intensity from samples taken over time. Treatment with a reagent including a fluorescent protein inhibits amyloid fibril formation by providing the reagent to an environment including amyloid monomers. The fluorescent protein binds to amyloid oligomers during the lag phase and/or elongation phase of amyloid fibril formation, preventing formation of mature amyloid fibrils.

Abstract: A centraliser comprises two collars that are connected by asymmetric spring bows. The spring bows each comprise two arcs, where the curvature of one arc is inverted with respect to the curvature of the other arc, one being concave and the other convex. The spring bows are in sets that are equidistantly spaced around the circumference of the collars, each set having the same configuration, and the opposite configuration to the spring bows in the other set. Upon insertion into a wellbore, one set of spring bows is therefore compressed before the other set. Upon compression, the deformation of the concave arc leads to mutual deformation of the convex arc, and the spring bows adopt a flatter configuration, enhancing the rotational freedom of the tubular.