Abstract: A flow of breathable gas is delivered to a subject through a patient interface assembly. An enhanced technique for determining whether the airway of subject is disengaged from the patient interface assembly. A model that provides predicted values of a dynamic property of the flow of breathable gas is fit to measured values of the dynamic property. The model and/or the fit of the predicted values to the measured values are then analyzed to determine whether or not the airway of the subject is disengaged from the patient interface assembly. This provide enhanced determination of these conditions even in implementations in which a restrictive patient interface assembly is used.

Abstract: The present disclosure pertains to a mechanical ventilator system configured to deliver a pressurized flow of breathable gas to the airway of a subject. The system is configured to generate the pressurized flow of breathable gas according to a volume control mode therapy regime that delivers a target tidal volume to the subject during inhalation. During an individual inhalation, the system is configured to determine and/or adjust an inspiratory pressure level of the pressurized flow of breathable gas of the volume control mode therapy regime. The inspiratory pressure level is adjusted such that during the inhalation the inspiratory pressure level is not reduced to impede respiratory effort by the subject responsive to the target tidal volume being exceeded during the inhalation. The system comprises one or more of a pressure generator, a subject interface, one or more sensors, one or more processors, a user interface, electronic storage, and/or other components.

Abstract: Systems and methods for providing respiratory support to a subject by intermittently delivering pressurized flow of breathable gas to a subject are described. A system may include, for example, a pressure generator, an interface appliance configured to communicate a flow of gas generated by the pressure generator to an airway of the subject, one or more sensors, and one or more processors configured to execute one or more computer program modules. The computer program modules may be configured, for example, to determine whether the subject is ready to receive the pressurized flow of breathable gas, to initiate and/or terminate delivery of the pressurized flow of breathable gas to the airway of the subject, and to control the pressure generator and the interface appliance so as to appropriately deliver the pressurized flow of breathable gas based on a prescribed therapy regimen designed to ventilate the subject.

Abstract: The present disclosure pertains to a mechanical ventilator system configured to deliver a pressurized flow of breathable gas to the airway of a subject. The system is configured to generate the pressurized flow of breathable gas according to a volume control mode therapy regime that delivers a target tidal volume to the subject during inhalation. During an individual inhalation, the system is configured to determine and/or adjust an inspiratory pressure level of the pressurized flow of breathable gas of the volume control mode therapy regime. The inspiratory pressure level is adjusted such that during the inhalation the inspiratory pressure level is not reduced to impede respiratory effort by the subject responsive to the target tidal volume being exceeded during the inhalation. The system comprises one or more of a pressure generator, a subject interface, one or more sensors, one or more processors, a user interface, electronic storage, and/or other components.

Abstract: A flow of breathable gas is delivered to a subject through a patient interface assembly. An enhanced technique for determining whether the airway of subject is disengaged from the patient interface assembly. A model that provides predicted values of a dynamic property of the flow of breathable gas is fit to measured values of the dynamic property. The model and/or the fit of the predicted values to the measured values are then analyzed to determine whether or not the airway of the subject is disengaged from the patient interface assembly. This provide enhanced determination of these conditions even in implementations in which a restrictive patient interface assembly is used.