Patents by Inventor Nathan Kohler

Nathan Kohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOTREXATE-MODIFIED NANOPARTICLES AND RELATED METHODS
    Publication number: 20120107246
    Abstract: Methotrexate-modified nanoparticles that target tumors, compositions that include the nanoparticles, methods of imaging tissues using the nanoparticles, and methods for treating tissues using the nanoparticles.
    Type: Application
    Filed: June 18, 2010
    Publication date: May 3, 2012
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Miqin Zhang, Shian-Jy Wang, Nathan Kohler, Yuh-Jiuan Lin, Conroy Sun
  • Nanoparticles having reactive ester groups covalently coupled thereto and related methods
    Patent number: 7666394
    Abstract: A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: February 23, 2010
    Assignee: University of Washington
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • NANOPARTICLES HAVING REACTIVE ESTER GROUPS COVALENTLY COUPLED THERETO AND RELATED METHODS
    Publication number: 20090060846
    Abstract: A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
    Type: Application
    Filed: November 5, 2008
    Publication date: March 5, 2009
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • Magnetic nanoparticle compositions and methods
    Patent number: 7462446
    Abstract: A nanoparticle having a core comprising a magnetic material and surface to which are covalently coupled a plurality of silane moieties, wherein each silane moiety comprises a polyalkylene oxide moiety. The nanoparticle can further include a targeting agent, a targeting agent and a diagnostic agent, or a targeting agent and a therapeutic agent. Methods for using the nanoparticle to detect and treat tissues of interest.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: December 9, 2008
    Assignee: University of Washington
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • METHOTREXATE-MODIFIED NANOPARTICLES AND RELATED METHODS
    Publication number: 20070269380
    Abstract: Methotrexate-modified nanoparticles that target tumors, compositions that include the nanoparticles, methods of imaging tissues using the nanoparticles, and methods for treating tissues using the nanoparticles.
    Type: Application
    Filed: October 10, 2006
    Publication date: November 22, 2007
    Applicants: Washington, University of, Industrial Technology Research Institute
    Inventors: Miqin Zhang, Shian-Jy Wang, Nathan Kohler, Yuh-Jiuan Lin, Conroy Sun
  • Magnetic nanoparticle compositions and methods
    Publication number: 20060216239
    Abstract: A nanoparticle having a core comprising a magnetic material and surface to which are covalently coupled a plurality of silane moieties, wherein each silane moiety comprises a polyalkylene oxide moiety. The nanoparticle can further include a targeting agent, a targeting agent and a diagnostic agent, or a targeting agent and a therapeutic agent. Methods for using the nanoparticle to detect and treat tissues of interest.
    Type: Application
    Filed: March 20, 2006
    Publication date: September 28, 2006
    Applicant: Washington, University of
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Gunn