Patents by Inventor Nathan Mark Sherer

Nathan Mark Sherer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240228961
    Abstract: Genetically modified CCNT1 and XPO1 genes encoding proteins that inhibit virus infection in cells. The genetically modified CCNT1 gene encodes a protein with a C261Y substitution with respect to the human CCNT1 protein. The genetically modified XPO1 gene encodes a protein with P411T, M412V, and/or F414S substitutions with respect to the human XPO1 protein. The genetically modified CCNT1 and XPO1 genes can be introduced in cells. The cells comprising the genetically modified CCNT1 and XPO1 genes can be introduced in a subject with a virus infection to treat the infection.
    Type: Application
    Filed: September 27, 2023
    Publication date: July 11, 2024
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Nathan Mark SHERER, Ryan Thomas BEHRENS
  • Publication number: 20240132842
    Abstract: Genetically modified CCNT1 and XPO1 genes encoding proteins that inhibit virus infection in cells. The genetically modified CCNT1 gene encodes a protein with a C261Y substitution with respect to the human CCNT1 protein. The genetically modified XPO1 gene encodes a protein with P411T, M412V, and/or F414S substitutions with respect to the human XPO1 protein. The genetically modified CCNT1 and XPO1 genes can be introduced in cells. The cells comprising the genetically modified CCNT1 and XPO1 genes can be introduced in a subject with a virus infection to treat the infection.
    Type: Application
    Filed: September 26, 2023
    Publication date: April 25, 2024
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Nathan Mark SHERER, Ryan Thomas BEHRENS
  • Patent number: 11845958
    Abstract: Genetically modified CCNT1 and XPO1 genes encoding proteins that inhibit virus infection in cells. The genetically modified CCNT1 gene encodes a protein with a C261Y substitution with respect to the human CCNT1 protein. The genetically modified XPO1 gene encodes a protein with P411T, M412V, and/or F414S substitutions with respect to the human XPO1 protein. The genetically modified CCNT1 and XPO1 genes can be introduced in cells. The cells comprising the genetically modified CCNT1 and XPO1 genes can be introduced in a subject with a virus infection to treat the infection.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: December 19, 2023
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Nathan Mark Sherer, Ryan Thomas Behrens
  • Patent number: 10968472
    Abstract: Disclosed are methods to measure the extent of viral infection and methods to measure latent viral reservoir in cells harboring or suspected of harboring such a reservoir.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: April 6, 2021
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Nathan Mark Sherer, Jordan Thomas Becker
  • Publication number: 20200071671
    Abstract: Genetically modified CCNT1 and XPO1 genes encoding proteins that inhibit virus infection in cells. The genetically modified CCNT1 gene encodes a protein with a C261Y substitution with respect to the human CCNT1 protein. The genetically modified XPO1 gene encodes a protein with P411T, M412V, and/or F414S substitutions with respect to the human XPO1 protein. The genetically modified CCNT1 and XPO1 genes can be introduced in cells. The cells comprising the genetically modified CCNT1 and XPO1 genes can be introduced in a subject with a virus infection to treat the infection.
    Type: Application
    Filed: September 5, 2019
    Publication date: March 5, 2020
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Nathan Mark SHERER, Ryan Thomas BEHRENS
  • Publication number: 20180037925
    Abstract: Disclosed are methods to measure the extent of viral infection and methods to measure latent viral reservoir in cells harboring or suspected of harboring such a reservoir.
    Type: Application
    Filed: August 1, 2017
    Publication date: February 8, 2018
    Inventors: Nathan Mark Sherer, Jordan Thomas Becker