Abstract: In one aspect of the invention, a downhole tool string component comprises a tubular body with a first and a second tool joint adapted to connect to adjacent tool string components, and a central bore adapted to pass drilling mud between the joints. A sleeve circumferentially disposed about an outer surface of the tubular body. The sleeve is rigidly attached to the outer surface at first and second sleeve ends and forming at least three stabilizer blades. A nuclear source and at least one nuclear detector are disposed within a gap formed between the inner surface of the sleeve and the outer surface of the tubular body.

Abstract: In one aspect of the invention, a downhole tool string component comprises a tubular body with a first and a second tool joint adapted to connect to adjacent tool string components, and a central bore adapted to pass drilling mud between the joints. A sleeve circumferentially disposed about an outer surface of the tubular body. The sleeve is rigidly attached to the outer surface at first and second sleeve ends and forming at least three stabilizer blades. A nuclear source and at least one nuclear detector are disposed within a gap formed between the inner surface of the sleeve and the outer surface of the tubular body.

Abstract: A bone plate assembly including at least one bone plate, polyaxially adjustable fixation elements and a polyaxially adjustable locking mechanism. A first plate includes at least one polyaxial element for lockable connection with a fixation pad, and a connection feature which allows the plate to translate and polyaxially rotate relative to the locking mechanism. A second plate includes at least one polyaxial element for connection with a fixation pad and a connection feature for non-rotatable connection with the locking mechanism. The locking mechanism allows translation and polyaxial adjustment of the first plate relative to the second plate and locks the first and second plates via a taper lock. The fixation pad includes a deflectable spacer configured to prevent premature locking of the pad. Methods for implantation of the bone plate assembly between two bone structures are disclosed. Instrumentation for implantation, compression and locking of the bone plate assembly is disclosed.

Abstract: An isolated polypeptide comprising a hydrogen generating enzyme attached to a heterologous ferredoxin is disclosed, as well as polynucleotides encoding same, nucleic acid constructs capable of expressing same and cells expressing same. A method for generating hydrogen using the isolated polypeptide is also disclosed.

Abstract: In one aspect of the present invention, a downhole power assembly has a downhole drill string component having a center mandrel with a through-bore adapted to accommodate a flow of drilling fluid. The component has an independent tubular battery cage disposed around the center mandrel. At least one battery is disposed in at least one bay formed in the tubular battery cage and a tubular sleeve is adapted to slide over and cover the tubular battery cage.

Abstract: In one aspect of the invention, a downhole tool string component comprises a tubular body with a first and a second tool joint adapted to connect to adjacent tool string components, and a central bore adapted to pass drilling mud between the joints. A sleeve circumferentially disposed about an outer surface of the tubular body. The sleeve is rigidly attached to the outer surface at first and second sleeve ends and forming at least three stabilizer blades. A nuclear source and at least one nuclear detector are disposed within a gap formed between the inner surface of the sleeve and the outer surface of the tubular body.

Abstract: In one aspect of the invention, a downhole tool string component comprises a tubular body with a first and a second tool joint adapted to connect to adjacent tool string components, and a central bore adapted to pass drilling mud between the joints. A sleeve circumferentially disposed about an outer surface of the tubular body. The sleeve is rigidly attached to the outer surface at first and second sleeve ends and forming at least three stabilizer blades. A nuclear source and at least one nuclear detector are disposed within a gap formed between the inner surface of the sleeve and the outer surface of the tubular body.

Abstract: In one aspect of the invention, a drill string comprises a drill bit with a body intermediate a shank and a working face, and the working face comprises at least one cutting element. A jack assembly is disposed within the drill bit body and comprises a jack element disposed on a distal end of the assembly. The jack element substantially protrudes from the working face and is adapted to move with respect to the bit body. At least one position feedback sensor is disposed proximate the jack assembly and is adapted to detect a position and/or orientation of the jack element.

Abstract: In one aspect of the invention, a drill string comprises a drill bit with a body intermediate a shank and a working face, and the working face comprises at least one cutting element. A jack assembly is disposed within the drill bit body and comprises a jack element disposed on a distal end of the assembly. The jack element substantially protrudes from the working face and is adapted to move with respect to the bit body. At least one position feedback sensor is disposed proximate the jack assembly and is adapted to detect a position and/or orientation of the jack element.

Abstract: In one aspect of the invention, a downhole tool string component comprises a tubular body with a first and a second tool joint adapted to connect to adjacent tool string components, and a central bore adapted to pass drilling mud between the joints. A sleeve circumferentially disposed about an outer surface of the tubular body. The sleeve is rigidly attached to the outer surface at first and second sleeve ends and forming at least three stabilizer blades. A nuclear source and at least one nuclear detector are disposed within a gap formed between the inner surface of the sleeve and the outer surface of the tubular body.

Abstract: In one aspect of the present invention, a downhole tool string component has a first and second threaded end on a mandrel, the first threaded end attached to a first sleeve and the second threaded end attached to a second sleeve. An intermediate sleeve assembly is disposed circumferentially around the mandrel and intermediate the first and second threaded ends, and the intermediate sleeve assembly is primarily isolated from stress of the first or second sleeve.

Abstract: In one embodiment of the invention, a downhole tool string component comprising a through bore running there through formed to accept drilling fluid. At least one mechanical actuation device is also disposed within the through bore. A guide channel is disposed within the through bore and comprises a geometry shaped to conduct the at least one mechanical actuation device. A switch is disposed within the guide channel in an original position and actuatable by the at least one mechanical actuation device to a subsequent position. A resettable mechanism is in contact with the switch wherein the resettable mechanism returns the switch to its original position. A receptacle may also be disposed within the through bore comprising a geometry shaped to accept the at least one mechanical actuation device.

Abstract: In one aspect of the invention a downhole tool string component has a segmented sleeve slideably attached over the exterior of a mandrel which is adapted for connection to an adjacent tool string component. An end of the sleeve is abutted against a shoulder element of the mandrel and an opposite end of the sleeve is axially loaded by a threaded element attached to the mandrel. The sleeve comprises at least one sleeve segment with an engagement end comprising at least one axial anti-rotation assembly adapted to transfer torque to an adjacent sleeve segment, the shoulder element, or the threaded element.

Abstract: In one embodiment of the invention, a downhole tool string component comprising a through bore running there through formed to accept drilling fluid. At least one mechanical actuation device is also disposed within the through bore. A guide channel is disposed within the through bore and comprises a geometry shaped to conduct the at least one mechanical actuation device. A switch is disposed within the guide channel in an original position and actuatable by the at least one mechanical actuation device to a subsequent position. A resettable mechanism is in contact with the switch wherein the resettable mechanism returns the switch to its original position. A receptacle may also be disposed within the through bore comprising a geometry shaped to accept the at least one mechanical actuation device.

Abstract: A soluble fusion protein is disclosed. The soluble fusion protein comprises at least one soluble polypeptide and a heterologous polypeptide being fused thereto, the heterologous polypeptide being normally insoluble and/or suboptimally expressed when expressed in a cell, wherein the at least one soluble polypeptide has an amino acid sequence at least 65 percent similar to SEQ ID NO: 1 and/or 2, as determined using the Standard protein-protein BLAST [blastp] software of the NCBI.

Abstract: A soluble fusion protein is disclosed. The soluble fusion protein comprises at least one soluble polypeptide and a heterologous polypeptide being fused thereto, the heterologous polypeptide being normally insoluble and/or suboptimally expressed when expressed in a cell, wherein the at least one soluble polypeptide has an amino acid sequence at least 65 percent similar to SEQ ID NO: 1 and/or 2, as determined using the Standard protein-protein BLAST [blastp] software of the NCBI.

Abstract: In one aspect of the present invention, a section of a drill string has a drill bit with a body intermediate a shank and a working face, the working face having at least one cutting element. A jack element is disposed within the drill bit body and has a distal end substantially protruding from the working face. A drive shaft is in communication with the jack element and a rotary source. The drive shaft has a first portion secured within a bore of a tool string component in the tool string and a second portion secured within a bore of the drill bit. The first and second portions of the drive shaft are connected at a pin and box connection wherein the first and second portions are automatically connected as the tool string component is mechanically coupled to the drill bit.

Abstract: In one aspect of the invention, a drill string comprises a drill bit with a body intermediate a shank and a working face, and the working face comprises at least one cutting element. A jack assembly is disposed within the drill bit body and comprises a jack element disposed on a distal end of the assembly. The jack element substantially protrudes from the working face and is adapted to move with respect to the bit body. At least one position feedback sensor is disposed proximate the jack assembly and is adapted to detect a position and/or orientation of the jack element.

Abstract: A downhole tool string component, having a tubular body with an outer diameter. A first, second, and third flange are disposed around the outer diameter of the tubular body at different axial locations. A first sleeve is disposed around the tubular body such that opposite ends of the first sleeve fit around at least a portion of the first and second flanges, forming a first sealed pocket around the outer diameter of the tubular body. A second sleeve is disposed around the tubular body such that opposite ends of the second sleeve fit around at least a portion of the second and third flanges, forming a second sealed pocket around the outer diameter of the tubular body.

Abstract: In one aspect, a downhole assembly has a downhole tool string component with a bore adapted to accommodate drilling mud. A fluid barrier is disposed within the bore and has a cylindrical portion substantially aligned with the bore. A drive shaft is sealed within and substantially coaxial with the cylindrical portion and has a first magnet disposed on its outer surface. A turbine assembly is disposed around the cylindrical portion of the fluid barrier and has an inner diameter and outer surface. The outer surface of the turbine assembly has a plurality of turbine blades. The inner diameter of the turbine assembly has a second magnet disposed within a region defined by the turbine blades and is in magnetic communication with the first magnet of the drive shaft, wherein when the drilling mud engages the turbine blades the first and second magnets rotate the drive shaft with the turbine assembly.