Abstract: The present invention provides methods of making a compound of formula II: or a pharmaceutically acceptable salt thereof, wherein R1, R2, and L are as defined and described herein.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein L and Ring A are as defined and described herein, compositions thereof, and methods of using the same.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein R1 and R5 are as defined and described herein, compositions thereof, and methods of using the same.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is as defined and described herein, compositions thereof, and methods of using the same.

Abstract: Described are methods and systems for powering an Otto-cycle engine using gasoline and compressed natural gas (CNG). The Otto-cycle engine can be powered by determining a quantity of the gasoline and a quantity of the CNG to deliver to a cylinder of the engine during an engine cycle such that combustion within the cylinder occurs at a pre-determined air-fuel ratio; delivering the quantity of the gasoline to the cylinder via a gasoline injector and delivering the quantity of the CNG to the cylinder via a CNG injector such that the gasoline and the CNG combust during the same combustion event; and combusting the gasoline and the CNG within the cylinder. Delivering CNG and gasoline to the cylinder using separate injectors allows the quantities of CNG and gasoline to vary in response to engine operating conditions, which allows the fuel mixture to be adjusted to satisfy engine power and emissions criteria.

Abstract: A system and method for measuring the liquid level in a tank or container is provided. The system can have a sensor string comprising a plurality of analog output hall-effect sensors and a computer readable memory containing sensor string information, a float having a magnetic field and positionable relative to the sensor string, and a controller containing at least one processing unit, at least one memory and a sensor string interface for connecting the controller to the sensor string. The system can be operative to obtain the sensor string information from the at least one memory of the sensor string, obtain a preloaded waveform indicating the output of a sensor relative to the position of the float and approximate the position of the float relative to the sensor string using the normalized output of at least one of the sensors and the preloaded waveform.

Abstract: As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.