Abstract: Disclosed herein are a group anchor system, subsea installation tool and method of install such group anchor systems. The group anchor system includes a template through which a plurality of vertical piles, such as helical piles, are passed, drilled into the seabed at one end and secured to the template at the other to provide a mooring anchor for an offshore asset. The installation tool is a modular tool designed to mate with the group anchor system. Each module including drive mechanism for engaging and driving a pile. The piles may be driven simultaneously, individually, or in groups as required for proper placement and leveling. Methods of using the installation tool are also disclosed.

Abstract: The present invention relates to a method for identifying specific binding partners (e.g. antibodies or antibody mimetics) which bind to a desired target polypeptide. In particular, the method involves expressing a library of specific binding partners in a population of mammalian cells, wherein each cell in the population of cells displays the target polypeptide on the outer surface of the cell, and identifying or isolating cells within the population of cells to which specific binding partners are bound.

Abstract: The present invention includes a storage container having side accessible drawers for the convenient access to contents therein. The storage container includes an inner shell and an outer shell, between which coolant may be placed. A freeze shelf may be placed into the container to aid in temperature control.

Abstract: A method for producing a mutant G-protein coupled receptor (GPCR) with increased stability relative to a parent GPCR, the method comprising making one or more mutations in the amino acid sequence that defines a parent GPCR, wherein (i) the one or more mutations are located within a window of/plus or minus 5 residues, where/is the position of amino acid residue 2.46 in the parent GPCR when the parent GPCR is a Class 1 GPCR, or where/is the position of an equivalent amino acid residue in the parent GPCR when the parent GPCR is a Class 2 or 3 GPCR, and/or (ii) the one or more mutations are located within an amino acid sequence of transmembrane helix 7 in the parent GPCR which amino acid sequence interacts with the window of/plus or minus 5 residues, to provide one or more mutants of the parent GPCR with increased stability.

Abstract: A method for producing a mutant G-protein coupled receptor (GPCR) with increased stability relative to a parent GPCR, the method comprising making one or more mutations in the amino acid sequence that defines a parent GPCR, wherein (i) the one or more mutations are located within a window of / plus or minus 5 residues, where / is the position of amino acid residue 2.46 in the parent GPCR when the parent GPCR is a Class 1 GPCR, or where / is the position of an equivalent amino acid residue in the parent GPCR when the parent GPCR is a Class 2 or 3 GPCR, and/or (ii) the one or more mutations are located within an amino acid sequence of transmembrane helix 7 in the parent GPCR which amino acid sequence interacts with the window of / plus or minus 5 residues, to provide one or more mutants of the parent GPCR with increased stability.

Abstract: Methods for browsing image data and systems using the same are provided. First, a plurality of image data is provided. A thumbnail is created for each of the image data, wherein the respective thumbnails have the same image height. Then, a filmstrip is created according to the thumbnails, and all or a part of the filmstrip is displayed in a touch-sensitive display unit to let users browse the thumbnails corresponding to the image data.