Abstract: The present disclosure is directed to an auto-sampling system with syringe, valve configurations, and control logic that allow automatic, inline matrix matching of calibration standards to samples. In implementations, this can be accomplished with three independent syringes connected to a valve system to dynamically introduce a carrier, diluent, and ultrapure stock matrix flows for each blank, standard, or sample.

Abstract: Systems and methods for automatic preconcentration of fluid samples using alternating dual holding loops are described. A system embodiment includes, but is not limited to, a first sample loop and a second sample loop alternately fluidically coupled with a sample source; a first valve to alternately introduce fluid from the sample source to the first sample loop and the second sample loop; a second valve to alternately receive fluid from the first sample loop and the second sample loop and to alternately provide access to the preconcentration column to fluid received from the first sample loop and the second sample loop; and a pump system configured to alternately introduce sample held in the first sample loop and sample held in the second sample loop to the preconcentration column via the first valve and the second valve.

Abstract: The present disclosure is directed to an auto-sampling system with syringe, valve configurations, and control logic that allow automatic, inline preparation of concentrated sulfuric acid and concentrated phosphoric acid for analytic analyses. In implementations, the auto-sampling system includes independent syringe pumps connected to a valve system to dynamically introduce carrier, diluent, buffer, and eluent flows according to one or more modes of operation.

Abstract: The present disclosure is directed to an auto-sampling system with syringe, valve configurations, and control logic that allow automatic, inline matrix matching of calibration standards to samples. In implementations, this accomplished with three independent syringes connected to a valve system to dynamically introduce carrier, diluent, and ultrapure stock matrix flows for each blank, standard, or sample.

Abstract: Valve assemblies are described that provide segmented shuttle of liquid into sample vessels and automatic mixing via bubbles in the segmented liquid. A valve assembly includes a first valve member having ports configured to receive a pressurized gas, a first fluid, and a second fluid. The valve assembly also includes a second valve member coupled adjacent to the first valve member. The second valve member comprises a plurality of channels configured to interface with the first valve member. In a first configuration, the first fluid is loaded into an external loop. In the second configuration, the second fluid is eluted from the column into a vial in a segmented stream via bubbles of pressurized gas. Bubbles of gas automatically mix the eluted sample fluid.

Abstract: Systems and methods for automatic sampling, digestion, and joining a plurality of sample introduction systems of a sample for subsequent analysis by ICP-MS are described.

Abstract: The present disclosure is directed to systems and methods for automated column sparging of preconcentration columns for analytic testing. A system embodiment includes, but is not limited to, a selection valve fluidically coupled with a gas source and with an eluent source, the selection valve including a mixing portion to mix gas from the gas source and eluent from the eluent source to provide a bubbled eluent stream; and a preconcentration column in fluid communication with the selection valve, the preconcentration column configured to receive the bubbled eluent stream from the selection valve and direct the bubbled eluent stream into an interior of the preconcentration column.

Abstract: Systems and methods are described to concentrate a remote sample for analysis. A sample concentration system embodiment includes, but is not limited to, a plurality of valves including at least a first valve, a second valve, and a third valve; a plurality of columns including at least a first column and a second column, the first column fluidically coupled to the first valve, the second column fluidically coupled to the second valve; and a flow meter coupled with the third valve, the flow meter fluidically coupled with each of the first column and the second column when the plurality of valves is in a first flow path configuration to measure an amount of the liquid sample passed through the first column and the second column, wherein the plurality of valves includes a second flow path configuration and a third flow path configuration.

Abstract: Systems and methods for automatic preconcentration of fluid samples using alternating dual holding loops are described. A system embodiment includes, but is not limited to, a first sample loop and a second sample loop alternately fluidically coupled with a sample source; a first valve to alternately introduce fluid from the sample source to the first sample loop and the second sample loop; a second valve to alternately receive fluid from the first sample loop and the second sample loop and to alternately provide access to the preconcentration column to fluid received from the first sample loop and the second sample loop; and a pump system configured to alternately introduce sample held in the first sample loop and sample held in the second sample loop to the preconcentration column via the first valve and the second valve.

Abstract: The present disclosure is directed to an auto-sampling system with syringe, valve configurations, and control logic that allow automatic, inline preparation of concentrated sulfuric acid and concentrated phosphoric acid for analytic analyzes. In implementations, the auto-sampling system includes independent syringe pumps connected to a valve system to dynamically introduce carrier, diluent, buffer, and eluent flows according to one or more modes of operation.

Abstract: Valve assemblies are described that provide segmented shuttle of liquid into sample vessels and automatic mixing via bubbles in the segmented liquid. A valve assembly includes a first valve member having ports configured to receive a pressurized gas, a first fluid, and a second fluid. The valve assembly also includes a second valve member coupled adjacent to the first valve member. The second valve member comprises a plurality of channels configured to interface with the first valve member. In a first configuration, the first fluid is loaded into an external loop. In the second configuration, the second fluid is eluted from the column into a vial in a segmented stream via bubbles of pressurized gas. Bubbles of gas automatically mix the eluted sample fluid.

Abstract: Systems and methods are described to concentrate a remote sample for analysis. A sample concentration system embodiment includes, but is not limited to, a plurality of valves including at least a first valve, a second valve, and a third valve; a plurality of columns including at least a first column and a second column, the first column fluidically coupled to the first valve, the second column fluidically coupled to the second valve; and a flow meter coupled with the third valve, the flow meter fluidically coupled with each of the first column and the second column when the plurality of valves is in a first flow path configuration to measure an amount of the liquid sample passed through the first column and the second column, wherein the plurality of valves includes a second flow path configuration and a third flow path configuration.

Abstract: A rotor, a valve assembly, and a method for using the rotor and valve assembly are described that provide a reversed flow path. In an implementation, a rotor that employs example techniques in accordance with the present disclosure includes a plurality of channels formed in a surface of the rotor, the surface configured to be adjacent to and interface with a stator having a plurality of ports, where at least one channel fluidically connects at least three of the plurality of ports.

Abstract: A system for determining an analyte by inductively coupled plasma mass spectrometry (ICPMS) includes a sample introduction device having a heated cyclonic spray chamber. The system is configured to introduce sample that includes a metal and/or a metalloid having an organic interferent. The system also includes an inductively coupled plasma mass spectrometry device with a collision/reaction cell configured to receive a mixture of gases including both ammonia and hydrogen. A method includes introducing a sample to plasma to produce a characteristic spectrum associated with an elemental composition of the sample. The method also includes introducing both ammonia and hydrogen to a collision/reaction cell to remove carbon-based interferences to detection of the sample prior to determining the elemental composition of the sample.

Abstract: Valve assemblies are described that provide segmented shuttle of liquid into sample vessels and automatic mixing via bubbles in the segmented liquid. A valve assembly includes a first valve member having ports configured to receive a pressurized gas, a first fluid, and a second fluid. The valve assembly also includes a second valve member coupled adjacent to the first valve member. The second valve member comprises a plurality of channels configured to interface with the first valve member. In a first configuration, the first fluid is loaded into an external loop. In the second configuration, the second fluid is eluted from the column into a vial in a segmented stream via bubbles of pressurized gas. Bubbles of gas automatically mix the eluted sample fluid.

Abstract: A rotor, a valve assembly, and a method for using the rotor and valve assembly are described that provide a reversed flow path. In an implementation, a rotor that employs example techniques in accordance with the present disclosure includes a plurality of channels formed in a surface of the rotor, the surface configured to be adjacent to and interface with a stator having a plurality of ports, where at least one channel fluidically connects at least three of the plurality of ports.

Abstract: A system for determining an analyte by inductively coupled plasma mass spectrometry (ICPMS) includes a sample introduction device having a heated cyclonic spray chamber. The system is configured to introduce sample that includes a metal and/or a metalloid having an organic interferent. The system also includes an inductively coupled plasma mass spectrometry device with a collision/reaction cell configured to receive a mixture of gases including both ammonia and hydrogen. A method includes introducing a sample to plasma to produce a characteristic spectrum associated with an elemental composition of the sample. The method also includes introducing both ammonia and hydrogen to a collision/reaction cell to remove carbon-based interferences to detection of the sample prior to determining the elemental composition of the sample.

Abstract: Valve assemblies are described that provide flow paths in substantially indirect opposition for fluids injected into the valve assemblies for mixing. A valve assembly includes a first valve member having ports configured to receive a first fluid and a second fluid. The valve assembly also includes a second valve member coupled adjacent to the first valve member. The valve assembly defines a first flow path for the first fluid and a second flow path for the second fluid. The first flow path extends from one of the ports of the first valve member toward an interface between the first valve member and the second valve member, and the second flow path extends from a channel defined by the second valve member toward the interface between the first valve member and the second valve member. The second flow path is in substantially indirect opposition to the first flow path.

Abstract: Valve assemblies are described that provide bursts of gas between fluids to furnish separation between the fluids. A valve assembly includes a first valve member having ports configured to connect to an external loop, an output, and a vent, and ports configured to receive a first fluid, a second fluid, and a pressurized gas. The valve assembly further includes a second valve member coupled adjacent the first valve member having channels configured to connect the external loop to the second fluid for charging the external loop with the second fluid, and to connect the external loop to the output for supplying the second fluid from the external loop to the output. The second valve member also has one or more channels for receiving a burst of the pressurized gas via a port of the first valve member and supplying the pressurized gas to the output and/or to the external loop.

Abstract: A sample introduction solution includes nitric acid in an amount between approximately 1 percent and 10 percent by volume, hydrochloric acid in an amount between approximately 0.1 percent and 4 percent by volume, sulfuric acid in an amount between approximately 0.1 percent and 4 percent by volume, and hydrogen peroxide in an amount between approximately 0.1 percent and 8 percent by volume.