Patents by Inventor Nathan Sharkey

Nathan Sharkey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CD19 ANTIBODIES AND MULTI-SPECIFIC BINDING PROTEINS
    Publication number: 20230037815
    Abstract: Provided herein are anti-CD 19 antibodies and multi-specific binding proteins that bind CD 19, CD3, and serum albumin. Also provided are pharmaceutical compositions comprising these antibodies or multi-specific binding proteins, expression vectors and host cells for making these antibodies or multi-specific binding proteins, and methods of use of these antibodies or multi-specific binding proteins in treating cancers.
    Type: Application
    Filed: December 11, 2020
    Publication date: February 9, 2023
    Inventors: Patrick A. Baeuerle, Jennifer Michaelson, Bochong Li, Naveen Mehta, Jonathan Belk, Nathan Sharkey, Bianka Prinz, Bradley M. Lunde, Nga Rewa Houston
  • IMPROVED CULTIVATION MEDIA AND PROCESS FOR IMPROVED PROTEIN PRODUCTION BY PICHIA STRAINS
    Publication number: 20150299648
    Abstract: The present invention provides optimized cell culture media and fed-batch cultivation processes to improve the viability and volumetric production of heterologous proteins in Pichia. The disclosed media and processes utilize a non-fermentable sugar or sugar alcohol as an osmoprotectant to improve the robustness of Pichia production strains during methanol inducible fermentation.
    Type: Application
    Filed: November 22, 2013
    Publication date: October 22, 2015
    Applicant: Merck Sharp & Dohme Corp
    Inventors: Sehoon Kim, Marc D'Anjou, Muralidhar R. Mallem, Ishaan Shandil, Adam Nylen, Nathan Sharkey, Seemab S. Shaikh