Patents by Inventor Nathan Thai

Nathan Thai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIRECT CONVERSION OF HUMAN MESENCHYMAL STEM CELLS TO HUMAN CARDIOMYOCYTES
    Publication number: 20230407261
    Abstract: The invention provides compositions comprising a ribonucleotide or ribonucleotides or a deoxyribonucleotide or deoxyribonucleotides encoding at least two cell fate determinants (CFD) selected from the group consisting of PBX2, ACTN2, POU2F1, HAND1, TRIM24, GATA4, PBX1, ZBTB39, HAND2, IKZF4, NROB2, NACA2, SMYD1, JUP, NEUROD1, CKMT2, TSHZ2, MITF, MYOCD, and PPARGC1B. The compositions are useful in the treatment of cardiac disorders and in reprogramming a mesenchymal stem cell (MSC) to an autologous induced cardiomyocyte (iCM).
    Type: Application
    Filed: June 8, 2023
    Publication date: December 21, 2023
    Inventors: David Tran, Son Bang Le, Nathan Thai