Patents by Inventor Nathan Tichovolsky

Nathan Tichovolsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LADDER ASSEMBLY AND SYSTEM FOR GENERATING DIVERSITY
    Publication number: 20090298130
    Abstract: The present invention provides novel methods of generating a nucleic acid molecule. In certain embodiments, a double stranded nucleic acid chunk is generated from a ladder complex comprising partially complementary oligonucleotides, which chunk is combined with a nucleic acid acceptor molecule. In certain embodiments, the assembled chunk/nucleic acid acceptor molecule complex may be propagated in vivo or in vitro. The present invention also provides improved systems for generating a plurality of nucleic acid molecules that differ at one or more nucleotide positions. In certain embodiments, the plurality of nucleic acid molecules encodes a polypeptide or portion of a polypeptide.
    Type: Application
    Filed: January 30, 2009
    Publication date: December 3, 2009
    Applicant: Modular Genetics, Inc.
    Inventors: Kevin Jarrell, Jonah Keegan, Nathan Tichovolsky, Bob Rogers
  • Ladder assembly and system for generating diversity
    Patent number: 7485423
    Abstract: The present invention provides novel methods of generating a nucleic acid molecule. In certain embodiments, a double stranded nucleic acid chunk is generated from a ladder complex comprising partially complementary oligonucleotides, which chunk is combined with a nucleic acid acceptor molecule. In certain embodiments, the assembled chunk/nucleic acid acceptor molecule complex may be propagated in vivo or in vitro. The present invention also provides improved systems for generating a plurality of nucleic acid molecules that differ at one or more nucleotide positions. In certain embodiments, the plurality of nucleic acid molecules encodes a polypeptide or portion of a polypeptide.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: February 3, 2009
    Assignee: Modular Genetics, Inc.
    Inventors: Kevin Jarrell, Jonah Keegan, Nathan Tichovolsky, Bob Rogers
  • Ladder assembly and system for generating diversity
    Publication number: 20060223081
    Abstract: The present invention provides novel methods of generating a nucleic acid molecule. In certain embodiments, a double stranded nucleic acid chunk is generated from a ladder complex comprising partially complementary oligonucleotides, which chunk is combined with a nucleic acid acceptor molecule. In certain embodiments, the assembled chunk/nucleic acid acceptor molecule complex may be propagated in vivo or in vitro. The present invention also provides improved systems for generating a plurality of nucleic acid molecules that differ at one or more nucleotide positions. In certain embodiments, the plurality of nucleic acid molecules encodes a polypeptide or portion of a polypeptide.
    Type: Application
    Filed: November 11, 2005
    Publication date: October 5, 2006
    Inventors: Kevin Jarrell, Jonah Keegan, Nathan Tichovolsky, Bob Rogers