Patents by Inventor Nathan Wilson
Nathan Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12090168Abstract: Compositions, e.g., pharmaceutical compositions, nutritional compositions, medical foods, and food ingredients, as well as their methods of use, are provided, for treating diseases associated with hyperammonemia, e.g., urea cycle disorders (UCD) and hepatic encephalopathy (HE), e.g., minimal HE (MHE) and overt HE (OHE), and modulating enzyme activities and levels of microbes and taxa, and metabolites (e.g., ammonia) in the microbiome of a subject.Type: GrantFiled: November 3, 2018Date of Patent: September 17, 2024Assignee: DSM Nutritional Products, LLCInventors: Molly Krisann Gibson, Nathan Wilson Stebbins, Ruth Thieroff-Ekerdt, Geoffrey A. von Maltzahn
-
Publication number: 20240033227Abstract: In some aspects, fusosome compositions and methods are described herein that comprise membrane enclosed preparations, comprising a fusogen. In some embodiments, the fusosome can fuse to the target cell, thereby delivering complex biologic agents to the target cell cytoplasm.Type: ApplicationFiled: January 13, 2023Publication date: February 1, 2024Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Michael Travis Mee, Jacob Rosenblum Rubens, Nathan Wilson Stebbins, Molly Krisann Gibson, Neal Francis Gordon, Bo Zhang, Kyle Marvin Trudeau, Brigham Jay Hartley, Tamar Rose Putiri, Kiana Mahdaviani, Matthew Milnes Dobbin
-
Publication number: 20230332145Abstract: The present disclosure relates generally to compositions of synthetic bifunctional molecules comprising a first domain that specifically binds to a target ribonucleic acid sequence and a second domain that specifically binds to a target protein, and uses thereof.Type: ApplicationFiled: March 24, 2021Publication date: October 19, 2023Applicant: Flagship Pioneering, Inc.Inventors: Nathan Wilson STEBBINS, Benjamin Andrew PORTNEY, Eric Bruno VALEUR, Chih-Chi Yuan, Mitchell Guttman
-
Patent number: 11753612Abstract: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.Type: GrantFiled: March 8, 2017Date of Patent: September 12, 2023Assignee: LanzaTech NZ, Inc.Inventors: Christophe Collet, Guy William Waters, Jason Carl Bromley, Justin Yi Yang, Jarod Nathan Wilson
-
Publication number: 20230167450Abstract: The present disclosure relates generally to compositions of synthetic bifunctional molecules comprising a first domain that specifically binds to a target ribonucleic acid and a second domain that specifically binds to a target protein, and uses thereof.Type: ApplicationFiled: April 21, 2021Publication date: June 1, 2023Applicant: Flagship Pioneering, Inc.Inventors: Nathan Wilson STEBBINS, Benjamin Andrew PORTNEY, Eric Bruno VALEUR, Jacob Rosenblum RUBENS, Kaveh DANESHVAR, Alexandra Rachael SNEIDER, Mitchell GUTTMAN
-
Publication number: 20230158156Abstract: The present disclosure relates generally to compositions of synthetic bifunctional molecules comprising a first domain that specifically binds to a target ribonucleic acid and a second domain that specifically binds to a target polypeptide, and uses thereof.Type: ApplicationFiled: April 21, 2021Publication date: May 25, 2023Applicant: Flagship Pioneering, Inc.Inventors: Nathan Wilson STEBBINS, Benjamin Andrew PORTNEY, Eric Bruno VALEUR, Jacob Rosenblum RUBENS, Kaveh DANESHVAR, Alexandra Rachael SNEIDER
-
Patent number: 11576872Abstract: In some aspects, fusosome compositions and methods are described herein that comprise membrane enclosed preparations, comprising a fusogen. In some embodiments, the fusosome can the target cell, thereby delivering complex biologic agents to the target cell cytoplasm.Type: GrantFiled: May 8, 2018Date of Patent: February 14, 2023Assignee: FLAGSHIP PIONEERING INNOVATIONS V, INC.Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Michael Travis Mee, Jacob Rosenblum Rubens, Nathan Wilson Stebbins, Molly Krisann Gibson, Neal Francis Gordon, Bo Zhang, Kyle Marvin Trudeau, Brigham Jay Hartley, Tamar Rose Putiri, Kiana Mahdaviani, Matthew Milnes Dobbin
-
Patent number: 11518190Abstract: A vehicle component such as an axle spindle or suspension beam (3) is connected to a tubular vehicle axle (1) by fitting a connector sleeve (2) onto the axle and subjecting the assembly to a crimping operation in which plural depressions (206,2018) are formed by indentation in the connector sleeve and the axle wall at the connection region (11,12) to fix the connector sleeve on the tubular axle. In the described proposals a solid lubricant (4) such as molybdenum disulphide is applied at the connection region between the connector sleeve (2) and axle (1), before crimping. The further vehicle component (3) is then connected to the connector sleeve (2) by welding.Type: GrantFiled: October 23, 2018Date of Patent: December 6, 2022Inventors: Shaun Macken, Sathya Babu, Nathan Wilson
-
Publication number: 20220233577Abstract: Compositions, e.g., pharmaceutical compositions, nutritional compositions, medical foods, and food ingredients, as well as their methods of use, are provided, for treating diseases associated with hyperammonemia, e.g., urea cycle disorders (UCD) and hepatic encephalopathy (HE), e.g., minimal HE (MHE) and overt HE (OHE), and modulating enzyme activities and levels of microbes and taxa, and metabolites (e.g., ammonia) in the microbiome of a subject.Type: ApplicationFiled: November 3, 2018Publication date: July 28, 2022Inventors: Molly Krisann Gibson, Nathan Wilson Stebbins, Ruth Thieroff-Ekerdt, Geoffrey A. von Maltzahn
-
Publication number: 20210187018Abstract: This disclosure provides, e.g., cytobiologic compositions and methods of use thereof. The cytobiologics can be used, e.g., to deliver a protein or nucleic acid to a target cell.Type: ApplicationFiled: December 7, 2018Publication date: June 24, 2021Applicant: FLAGSHIP PIONEERING INNOVATIONS V, INC.Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael Travis Mee, Nathan Wilson Stebbins, Molly Krisann Gibson, Neal Francis Gordon, Bo Zhang, Kyle Marvin Trudeau, Brigham Jay Hartley, Tamar Rose Putiri, Kiana Mahdaviani, Jagesh Vijaykumar Shah, Michael Connor, Peter Anthony Jones
-
Patent number: 10807430Abstract: An axle/suspension system (1) has an axle (5) supported from the frame of the vehicle by a pair of rigid longitudinal beams (4) pivoted to frame hangers (3). Air springs (7) and shock absorbers (8) connect between the rigid beams (4) and the frame above to control suspension movement. The axle/suspension system is particularly suited as a mid-lift axle on the tractor of a tractor-trailer vehicle. A characteristic feature is the pivotal connection (21) between each hanger (3) and beam (4), which is through a resilient bush (6) having a compliance ratio—being a ratio of the longitudinal spring rate to the vertical spring rate—of at least 10:1.Type: GrantFiled: December 9, 2016Date of Patent: October 20, 2020Assignee: Hendrickson United Kingdom LtdInventors: Sathya Babu, Nathan Wilson, Gerhard Seck
-
Publication number: 20200247183Abstract: A vehicle component such as an axle spindle or suspension beam (3) is connected to a tubular vehicle axle (1) by fitting a connector sleeve (2) onto the axle and subjecting the assembly to a crimping operation in which plural depressions (206,2018) are formed by indentation in the connector sleeve and the axle wall at the connection region (11,12) to fix the connector sleeve on the tubular axle. In the described proposals a solid lubricant (4) such as molybdenum disulphide is applied at the connection region between the connector sleeve (2) and axle (1), before crimping. The further vehicle component (3) is then connected to the connector sleeve (2) by welding.Type: ApplicationFiled: October 23, 2018Publication date: August 6, 2020Inventors: Shaun Macken, Sathya Babu, Nathan Wilson
-
Publication number: 20200060980Abstract: In some aspects, fusosome compositions and methods are described herein that comprise membrane enclosed preparations, comprising a fusogen. In some embodiments, the fusosome can the target cell, thereby delivering complex biologic agents to the target cell cytoplasm.Type: ApplicationFiled: May 8, 2018Publication date: February 27, 2020Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Michael Travis Mee, Jacob Rosenblum Rubens, Nathan Wilson Stebbins, Molly Krisann Gibson, Neal Francis Gordon, Bo Zhang, Kyle Marvin Trudeau, Brigham Jay Hartley, Tamar Rose Putiri, Kiana Mahdaviani, Matthew Milnes Dobbin
-
Patent number: 10526375Abstract: The present invention provides, among other things, systems (e.g., comprising compositions and/or methods) for diagnosis, prophylaxis, treatment, prevention, and/or characterization of influenza transmission and/or infection. The present invention also provides methods for monitoring influenza variants for their potential to present a pandemic risk to humans.Type: GrantFiled: June 5, 2014Date of Patent: January 7, 2020Assignee: Massachusetts Institute of TechnologyInventors: Kannan Tharakaraman, Rahul Raman, Akila Jayaraman, Nathan Wilson Stebbins, Ram Sasisekharan
-
Publication number: 20180354330Abstract: An axle/suspension system (1) has an axle (5) supported from the frame of the vehicle by a pair of rigid longitudinal beams (4) pivoted to frame hangers (3). Air springs (7) and shock absorbers (8) connect between the rigid beams (4) and the frame above to control suspension movement. The axle/suspension system is particularly suited as a mid-lift axle on the tractor of a tractor-trailer vehicle. A characteristic feature is the pivotal connection (21) between each hanger (3) and beam (4), which is through a resilient bush (6) having a compliance ratio—being a ratio of the longitudinal spring rate to the vertical spring rate—of at least 10:1.Type: ApplicationFiled: December 9, 2016Publication date: December 13, 2018Inventors: Sathya Babu, Nathan Wilson, Gerhard Seck
-
Publication number: 20170175064Abstract: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.Type: ApplicationFiled: March 8, 2017Publication date: June 22, 2017Inventors: Christophe Collet, Guy William Waters, Jason Carl Bromley, Justin Yi Yang, Jarod Nathan Wilson
-
Patent number: 9617566Abstract: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.Type: GrantFiled: July 11, 2014Date of Patent: April 11, 2017Assignee: LANZATECH NEW ZEALAND LIMITEDInventors: Christophe Collet, Guy William Waters, Jason Carl Bromley, Justin Yi Yang, Jarod Nathan Wilson
-
Publication number: 20160010116Abstract: Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.Type: ApplicationFiled: July 11, 2014Publication date: January 14, 2016Inventors: Christophe Collet, Guy William Waters, Jason Carl Bromley, Justin Yi Yang, Jarod Nathan Wilson
-
Publication number: 20140335504Abstract: The present invention provides, among other things, technologies and methodologies for detection, treatment, and/or prevention of influenza transmission and/or infection. The present invention also provides technologies for monitoring influenza HA variants with particular degrees of susceptibility to mutation for human adaptation.Type: ApplicationFiled: February 7, 2014Publication date: November 13, 2014Applicant: Massachusetts Institute of TechnologyInventors: Ram Sasisekharan, Rahul Raman, Kannan Tharakaraman, Karthik Viswanathan, Nathan Wilson Stebbins
-
Publication number: 20120048312Abstract: A pipe cleaning assembly includes a main shaft defining an inner bore aligned along a first axis, the inner bore being able to couple in fluid communication with coiled tubing. A slide shaft is disposed around the main shaft, the slide shaft having a forward end, a rear end, and a plurality of fluid pathways. Each of the fluid pathways is in fluid communication between the forward end of the slide shaft and the read end of the slide shaft. Each of the fluid pathways has a forward end able to direct fluid toward an inner surface of a pipe. The slide shaft is able to slide along the main shaft between a first position and a second position, in the direction of the first axis. The first position permits fluid flow through the plurality of fluid pathways, from the rear end of the slide shaft to the forward end of the slide shaft. The second position restricts fluid flow through the plurality of fluid pathways, from the forward end of the slide shaft to the rear end of the slide shaft.Type: ApplicationFiled: August 25, 2010Publication date: March 1, 2012Applicant: Slider LLCInventors: Harold W. Wilson, William S. Jones, Joseph Nathan Wilson, Weldon Wilson