Patents by Inventor Nathan Wrench
Nathan Wrench has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11969541Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.Type: GrantFiled: June 17, 2019Date of Patent: April 30, 2024Assignee: Smith & Nephew PLCInventors: Benjamin Gordon, Jake Turner, Edward Yerbury Hartwell, Stephen Jacob, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Publication number: 20240100238Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.Type: ApplicationFiled: November 29, 2023Publication date: March 28, 2024Inventors: Benjamin Gordon, Jake Turner, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Publication number: 20230103942Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.Type: ApplicationFiled: December 9, 2022Publication date: April 6, 2023Inventors: Nathan Wrench, William Mainwaring-Burton, Chris Butcher, Nick Harrison
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Patent number: 11525813Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.Type: GrantFiled: January 31, 2018Date of Patent: December 13, 2022Assignee: Bio-Rad Laboratories, Inc.Inventors: Nathan Wrench, William Mainwaring-Burton, Chris Butcher, Nick Harrison
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Patent number: 10646265Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.Type: GrantFiled: December 15, 2014Date of Patent: May 12, 2020Assignee: Cryotherapeutics GmbHInventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
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Publication number: 20200000983Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.Type: ApplicationFiled: June 17, 2019Publication date: January 2, 2020Inventors: Benjamin Gordon, Jake Turner, Edward Yerbury Hartwell, Stephen Jacob, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Patent number: 10328187Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.Type: GrantFiled: August 4, 2016Date of Patent: June 25, 2019Assignee: Smith & Nephew PLCInventors: Benjamin Gordon, Jake Turner, Edward Hartwell, Stephen Jacob, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Publication number: 20180238839Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.Type: ApplicationFiled: January 31, 2018Publication date: August 23, 2018Inventors: Nathan Wrench, William Mainwaring-Burton, Chris Butcher, Nick Harrison
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Patent number: 9921193Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.Type: GrantFiled: March 14, 2014Date of Patent: March 20, 2018Assignee: Bio-Rad Laboratories, Inc.Inventors: Nathan Wrench, William Mainwaring-Burton, Chris Butcher, Nick Harrison
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Patent number: 9889394Abstract: A filter device having a sonotrode connected to a filtration assembly. The filtration assembly has a filter body having a fluid passage. The filter body has a filter across the fluid passage. The filter assembly has a resonant frequency and the sonotrode is adapted to vibrate the filter assembly at or near the resonant frequency.Type: GrantFiled: April 30, 2014Date of Patent: February 13, 2018Assignee: Bio-Rad Laboratories, Inc.Inventors: Richard Day, Michael Burcher, Nathan Wrench, Marek Myszko, Matthew Hayes
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Publication number: 20160361106Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.Type: ApplicationFiled: December 15, 2014Publication date: December 15, 2016Applicant: CRYOTHERAPEUTICS GMBHInventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
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Publication number: 20160339156Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.Type: ApplicationFiled: August 4, 2016Publication date: November 24, 2016Inventors: Benjamin Gordon, Jake Turner, Edward Hartwell, Stephen Jacob, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Patent number: 9459035Abstract: A refrigeration device is provided that includes a housing enclosing an interior and an assembly in the interior having a storage compartment for chunks of ice and a stirrer. The stirrer is rotatable about an axis that extends through the storage compartment to move chunks of ice contained in the storage compartment in relation to each other and to move ice towards a dispensing passage that extends through the housing. A closable flap is interposed between the storage compartment and the dispensing passage.Type: GrantFiled: November 22, 2007Date of Patent: October 4, 2016Assignee: BSH Hausgeraete GmbHInventors: Martin Buchstab, Irene Dumkow, Adolf Feinauer, Klaus Flinner, Bernd Heger, Helen Lewis, Peter Nalbach, Martin PĆ¼njer, Craig Duncan Webster, Nathan Wrench, Kasim Yazan
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Patent number: 9408954Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.Type: GrantFiled: August 17, 2012Date of Patent: August 9, 2016Assignee: SMITH & NEPHEW PLCInventors: Benjamin Gordon, Jake Turner, Edward Hartwell, Stephen Jacob, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Patent number: 9320988Abstract: Disclosed herein is an apparatus for debubbling or degassing a liquid. The apparatus includes a tube with a hollow lumen and a gas-permeable, liquid-impermeable wall surrounding the lumen. Also disclosed is a method for performing the debubbling or degassing, wherein the liquid is passed through the tube and gas is allowed to escape through the wall of the tube. The application additionally discloses a system for debubbling or degassing a liquid, wherein a pump is connected to the upstream end of the tube and a device to impede the flow of liquid out the tube is connected to the downstream end.Type: GrantFiled: March 13, 2014Date of Patent: April 26, 2016Assignee: BIO-RAD LABORATORIES, INC.Inventors: Nathan Wrench, William Mainwaring-Burton
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Patent number: 9243837Abstract: A dispensing device for free-flowing or pourable products, in particular in a refrigeration device. Said dispensing device has a feed pipe for a pourable product, comprising an exit opening and a shut-off flap that is situated at the exit opening, and an outlet for the free-flowing product, said outlet being attached to the flap and displaceable with the latter.Type: GrantFiled: October 31, 2006Date of Patent: January 26, 2016Assignee: BSH Hausgeraete GmbHInventors: Martin Buchstab, Irene Dumkow, Adolf Feinauer, Klaus Flinner, Bernd Heger, Marek Myszko, Peter Nalbach, Nathan Wrench, Kasim Yazan
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Patent number: 8974429Abstract: A method and apparatus for alerting a user of topical negative pressure therapy apparatus to a full waste canister condition are described, the apparatus comprising a device having vacuum pump means and a waste canister connected to the device and the waste canister operably connected to a wound dressing by aspiration conduit means for aspirating fluid from the wound, the aspiration conduit means, the waste canister and the device providing a fluid flow path therethrough and the vacuum pump means providing fluid flow through the apparatus, the apparatus further comprising fluid flow restriction means in the fluid flow path of said vacuum pump and fluid pressure sensing means upstream and downstream of said fluid flow restriction means.Type: GrantFiled: June 27, 2008Date of Patent: March 10, 2015Assignee: Smith & Nephew PLCInventors: Benjamin Gordon, Jake Turner, Nathan Wrench, Edward Vernon-Harcourt, David Harris
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Publication number: 20140326080Abstract: A filter device having a sonotrode connected to a filtration assembly. The filtration assembly has a filter body having a fluid passage. The filter body has a filter across the fluid passage. The filter assembly has a resonant frequency and the sonotrode is adapted to vibrate the filter assembly at or near the resonant frequency.Type: ApplicationFiled: April 30, 2014Publication date: November 6, 2014Applicant: Bio-Rad Laboratories, Inc.Inventors: Richard Day, Michael Burcher, Nathan Wrench, Marek Myszko, Matthew Hayes
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Publication number: 20140260970Abstract: Disclosed herein is an apparatus for debubbling or degassing a liquid. The apparatus includes a tube with a hollow lumen and a gas-permeable, liquid-impermeable wall surrounding the lumen. Also disclosed is a method for performing the debubbling or degassing, wherein the liquid is passed through the tube and gas is allowed to escape through the wall of the tube. The application additionally discloses a system for debubbling or degassing a liquid, wherein a pump is connected to the upstream end of the tube and a device to impede the flow of liquid out the tube is connected to the downstream end.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Applicant: Bio-Rad Laboratories, Inc.Inventors: Nathan Wrench, William Mainwaring-Burton
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Publication number: 20140261868Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Bio-Rad Laboratories, Inc.Inventors: Nathan Wrench, William Mainwaring-Burton, Chris Butcher, Nick Harrison