Patents by Inventor Nathanael Paul McCurley

Nathanael Paul McCurley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for generating an immune response to treat or prevent malaria
    Patent number: 11857611
    Abstract: The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
    Type: Grant
    Filed: April 21, 2022
    Date of Patent: January 2, 2024
    Assignee: Geovax, Inc.
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • Methods for generating a Zikv immune response utilizing a recombinant modified vaccina Ankara vector encoding the NS1 protein
    Patent number: 11638750
    Abstract: The compositions and methods are described for generating an immune response to a flavivirus such as Zika virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Flavivirus (such as a member of species Zika virus), in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by Flavivirus.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: May 2, 2023
    Assignee: Geovax, Inc.
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • VACCINIA VIRAL VECTORS ENCODING CHIMERIC VIRUS LIKE PARTICLES
    Publication number: 20230040403
    Abstract: The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 9, 2023
    Applicant: GeoVax, Inc.
    Inventors: Harriet Robinson, Arban Domi, Michael Hellerstein, Farshad Guirakhoo, Nathanael Paul McCurley
  • COMPOSITIONS AND METHODS FOR GENERATING AN IMMUNE RESPONSE TO TREAT OR PREVENT MALARIA
    Publication number: 20220313808
    Abstract: The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
    Type: Application
    Filed: April 21, 2022
    Publication date: October 6, 2022
    Applicant: Geovax, Inc
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • Vaccinia viral vectors encoding chimeric virus like particles
    Patent number: 11413341
    Abstract: The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: August 16, 2022
    Assignee: Geovax, Inc.
    Inventors: Harriet Robinson, Arban Domi, Michael Hellerstein, Farshad Guirakhoo, Nathanael Paul McCurley
  • Compositions and methods for generating an immune response to treat or prevent malaria
    Patent number: 11311612
    Abstract: The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: April 26, 2022
    Assignee: Geovax, Inc.
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • Compositions and methods for generating an immune response to a tumor associated antigen
    Patent number: 11278607
    Abstract: The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: March 22, 2022
    Assignee: Geovax, Inc.
    Inventors: Harriet Robinson, Arban Domi, Michael Hellerstein, Farshad Guirakhoo, Nathanael Paul McCurley
  • Compositions and Methods for Generating an Immune Response to a Flavivirus
    Publication number: 20210100891
    Abstract: The compositions and methods are described for generating an immune response to a Flavivirus such as Zika virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Flavivirus (such as a member of species Zika virus), in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by Flavivirus.
    Type: Application
    Filed: August 24, 2020
    Publication date: April 8, 2021
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • VACCINIA VIRAL VECTORS ENCODING CHIMERIC VIRUS LIKE PARTICLES
    Publication number: 20200289633
    Abstract: The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered.
    Type: Application
    Filed: February 20, 2020
    Publication date: September 17, 2020
    Applicant: GeoVax, Inc.
    Inventors: Harriet Robinson, Arban Domi, Michael Hellerstein, Farshad Guirakhoo, Nathanael Paul McCurley
  • Compositions and Methods for Generating an Immune Response to Treat or Prevent Malaria
    Publication number: 20200282036
    Abstract: The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
    Type: Application
    Filed: September 18, 2018
    Publication date: September 10, 2020
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • Compositions and Methods for Generating an Immune Response to a Tumor Associated Antigen
    Publication number: 20190290745
    Abstract: The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
    Type: Application
    Filed: January 9, 2017
    Publication date: September 26, 2019
    Inventors: Harriet Robinson, Arban Domi, Michael Hellerstein, Farshad Guirakhoo, Nathanael Paul McCurley
  • Compositions and Methods for Generating an Immune Response to a Flavivirus
    Publication number: 20190030157
    Abstract: The compositions and methods are described for generating an immune response to a flavivirus such as Zika virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Flavivirus (such as a member of species Zika virus), in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by Flavivirus.
    Type: Application
    Filed: February 1, 2017
    Publication date: January 31, 2019
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley