Patents by Inventor Nathaniel D. Huebsch

Nathaniel D. Huebsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viscoelastic hydrogels with fast stress relaxation
    Patent number: 11806441
    Abstract: Provided are fast relaxing hydrogels that are useful for regulating cell behavior and enhancing tissue regeneration, e.g., bone regeneration.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: November 7, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Luo Gu, Ovijit Chaudhuri, Nathaniel D. Huebsch, David J. Mooney, Max Carlton Darnell, Simon Young
  • INJECTABLE, PORE-FORMING HYDROGELS FOR MATERIALS-BASED CELL THERAPIES
    Publication number: 20220192986
    Abstract: The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time.
    Type: Application
    Filed: November 9, 2021
    Publication date: June 23, 2022
    Applicant: President and Fellows of Harvard College
    Inventors: Nathaniel D. Huebsch, Christopher M. Madl, Kangwon Lee, Maria M. Xu, David J. Mooney
  • Injectable, pore-forming hydrogels for materials-based cell therapies
    Patent number: 11202759
    Abstract: The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: December 21, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Nathaniel D. Huebsch, Christopher M. Madl, Kangwon Lee, Maria M. Xu, David J. Mooney
  • VISCOELASTIC HYDROGELS WITH FAST STRESS RELAXATION
    Publication number: 20210308322
    Abstract: Provided are fast relaxing hydrogels that are useful for regulating cell behavior and enhancing tissue regeneration, e.g., bone regeneration.
    Type: Application
    Filed: June 15, 2021
    Publication date: October 7, 2021
    Inventors: Luo Gu, Ovijit Chaudhuri, Nathaniel D. Huebsch, David J. Mooney, Max Carlton Darnell, Simon Young
  • Viscoelastic hydrogels with fast stress relaxation
    Patent number: 11065362
    Abstract: Provided are fast relaxing hydrogels that are useful for regulating cell behavior and enhancing tissue regeneration, e.g., bone regeneration.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: July 20, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Luo Gu, Ovijit Chaudhuri, Nathaniel D. Huebsch, David J. Mooney, Max Carlton Darnell, Simon Young
  • Harnessing cell dynamics to engineer materials
    Patent number: 9297005
    Abstract: The invention features synthetic materials and methods for inducing cell behavior. Matrix materials induce cell differentiation and cell manipulation based on mechanical and physical characteristics of the materials rather than chemical characteristics.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: March 29, 2016
    Assignee: President and Fellows of Harvard College
    Inventors: Nathaniel D. Huebsch, David J. Mooney
  • VISCOELASTIC HYDROGELS WITH FAST STRESS RELAXATION
    Publication number: 20150359928
    Abstract: Provided are fast relaxing hydrogels that are useful for regulating cell behavior and enhancing tissue regeneration, e.g., bone regeneration.
    Type: Application
    Filed: June 12, 2015
    Publication date: December 17, 2015
    Inventors: Luo Gu, Ovijit Chaudhuri, Nathaniel D. Huebsch, David J. Mooney, Max Carlton Darnell, Simon Young
  • Injectable, Pore-Forming Hydrogels for Materials-Based Cell Therapies
    Publication number: 20140079752
    Abstract: The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surrounding hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time.
    Type: Application
    Filed: October 6, 2011
    Publication date: March 20, 2014
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Nathaniel D. Huebsch, Christopher M. Madl, Kangwon Lee, Maria M. Xu, David J. Mooney
  • Harnessing Cell Dynamics to Engineer Materials
    Publication number: 20120122218
    Abstract: The invention features synthetic materials and methods for inducing cell behavior. Matrix materials induce cell differentiation and cell manipulation based on mechanical and physical characteristics of the materials rather than chemical characteristics.
    Type: Application
    Filed: April 13, 2010
    Publication date: May 17, 2012
    Applicant: President and Fellows of Harvard College
    Inventors: Nathaniel D. Huebsch, David J. Mooney
  • ON-DEMAND AND REVERSIBLE DRUG RELEASE BY EXTERNAL CUE
    Publication number: 20120035531
    Abstract: The invention provides a method to release drugs from a polymer matrix upon demand without degrading the matrix. By applying ultrasound to a self-healable polymer matrix in physiological environment, compounds of both low-molecular and high-molecular weights encapsulated in the matrix are delivered at controlled rates, while the integrity and stiffness of the matrix are unaffected.
    Type: Application
    Filed: February 1, 2010
    Publication date: February 9, 2012
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Xuanhe Zhao, Nathaniel D. Huebsch, David J. Mooney, Zhigang Suo