Abstract: A microfluidic chip for use in in-vitro brain models is disclosed. The chip includes a microcapillary scaffold having a scaffold base and a scaffold vasculature. The chip includes a plate having wells, and the microcapillary scaffold is secured in the well. The chip also includes a microfluidic interface system attached to the microcapillary scaffold, which includes heat-shrink tubing and hypodermic needles. An external fluidic system is connected to the microfluidic interface system for supplying fluid for perfusion through the microcapillary scaffold. The microcapillary scaffold includes a customizable capillary membrane and a customizable polygonal support or a lattice support. The scaffold base is made from a rigid hybrid polymer resin, while the scaffold vasculature is made from a rigid hybrid polymer resin, a PEGDA resin or an elastomeric resin.

Abstract: A valve collar for a downhole packer includes a flow path. The flow path includes an opening valve and closing valve. The valve collar further includes a lockout valve piston. The lockout valve piston is positioned such that in an unset position, the flow path is open and in a set position, the flow path is blocked by the lockout valve piston. The lockout valve piston may be adapted to be shifted from the unset position to the set position by a pressure spike inside the valve collar. The lockout valve piston may be held in the unset position by a temporary restraint.

Abstract: A valve collar for a downhole packer includes a flow path. The flow path includes an opening valve and closing valve. The valve collar further includes a lockout valve piston. The lockout valve piston is positioned such that in an unset position, the flow path is open and in a set position, the flow path is blocked by the lockout valve piston. The lockout valve piston may be adapted to be shifted from the unset position to the set position by a pressure spike inside the valve collar. The lockout valve piston may be held in the unset position by a temporary restraint.

Abstract: A valve collar for a downhole packer includes a flow path. The flow path includes an opening valve and closing valve. The valve collar further includes a lockout valve piston. The lockout valve piston is positioned such that in an unset position, the flow path is open and in a set position, the flow path is blocked by the lockout valve piston. The lockout valve piston may be adapted to be shifted from the unset position to the set position by a pressure spike inside the valve collar. The lockout valve piston may be held in the unset position by a temporary restraint.

Abstract: A valve collar for a downhole packer includes a flow path. The flow path includes an opening valve and closing valve. The valve collar further includes a lockout valve piston. The lockout valve piston is positioned such that in an unset position, the flow path is open and in a set position, the flow path is blocked by the lockout valve piston. The lockout valve piston may be adapted to be shifted from the unset position to the set position by a pressure spike inside the valve collar. The lockout valve piston may be held in the unset position by a temporary restraint.

Abstract: An ankle sprain reduction system includes a shoe having a brace incorporated in the shoe. The brace has a base plate with medial and lateral sides extending upwardly from a lower base portion. Medial and lateral support plates are pivotally mounted to each of the sides at a location below the malleoli. The lower base portion is of a length that extends from the heel to just proximal to the metatarsalphalangeal joints of the foot.