Patents by Inventor Nathaniel Hogrebe

Nathaniel Hogrebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IMPROVING SC-BETA CELLS OR ENHANCING THEIR UTILITY
    Publication number: 20230392124
    Abstract: Among the various aspects of the present disclosure is the provision of methods and compositions for the generation of cells of endodermal lineage and beta cells and uses thereof.
    Type: Application
    Filed: April 16, 2021
    Publication date: December 7, 2023
    Applicant: Washington University
    Inventors: Jeffrey Millman, Kristina Maxwell, Nathaniel Hogrebe, Leonardo Velazco-Cruz, Daniel Veronese Paniagua
  • DEFINED MATRIX FOR THE DIFFERENTIATION OF ISLETS
    Publication number: 20230340417
    Abstract: Among the various aspects of the present disclosure is the provision of methods and compositions for the generation of cells of endodermal lineage and beta cells and uses thereof.
    Type: Application
    Filed: April 20, 2023
    Publication date: October 26, 2023
    Inventors: Nathaniel Hogrebe, Jeffrey Millman
  • METHODS AND COMPOSITIONS FOR GENERATING CELLS OF ENDODERMAL LINEAGE AND BETA CELLS AND USES THEREOF
    Publication number: 20210207099
    Abstract: Among the various aspects of the present disclosure is the provision of methods and compositions for the generation of cells of endodermal lineage and beta cells and uses thereof.
    Type: Application
    Filed: May 16, 2019
    Publication date: July 8, 2021
    Inventors: Jeffrey R. Millman, Nathaniel Hogrebe, Jiwon Song, Leonardo Velazco-Cruz
  • Collapsible anvil head and stapling apparatus
    Patent number: 9782176
    Abstract: Various implementations of the invention provide for a one-piece surgical stapling apparatus that includes a stapler head and an anvil head assembly. The anvil head assembly is tiltable between a tilted position and a transverse position, and anvil plates of the anvil head assembly are moveable about one or more hinges between a closed and an open position. When in the tilted and closed positions, the anvil assembly has a reduced footprint that allows the anvil assembly to be passed directly through a trocar and holes created in the bodily tissues, which eliminates the need for separate placement of the anvil head. At the site of the anastomosis, the anvil head assembly can be moved to the transverse and open positions, and the stapling head may be engaged to fire staples against the anvil head.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: October 10, 2017
    Assignee: Ohio State Innovation Foundation
    Inventors: Mark Tyler Nelson, Nathaniel Hogrebe, Christopher Gordon Scheitlin, Xiaoli Liu, Joshua Hoffman
  • COLLAPSIBLE ANVIL HEAD AND STAPLING APPARATUS
    Publication number: 20140131420
    Abstract: Various implementations of the invention provide for a one-piece surgical stapling apparatus that includes a stapler head and an anvil head assembly. The anvil head assembly is tiltable between a tilted position and a transverse position, and anvil plates of the anvil head assembly are moveable about one or more hinges between a closed and an open position. When in the tilted and closed positions, the anvil assembly has a reduced footprint that allows the anvil assembly to be passed directly through a trocar and holes created in the bodily tissues, which eliminates the need for separate placement of the anvil head. At the site of the anastomosis, the anvil head assembly can be moved to the transverse and open positions, and the stapling head may be engaged to fire staples against the anvil head.
    Type: Application
    Filed: November 13, 2013
    Publication date: May 15, 2014
    Applicant: OHIO STATE INNOVATION FOUNDATION
    Inventors: Mark Tyler Nelson, Nathaniel Hogrebe, Christopher Gordon Scheitlin, Xiaoli Liu, Joshua Hoffman