Patents by Inventor Nathaniel M. Sims

Nathaniel M. Sims has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180242916
    Abstract: A system and method for monitoring a subject are provided. In some aspects, a provided electroencephalogram (“EEG”) system includes an electrode patch assembly configured to attach to a subject's skin, the assembly including a flexible circuit layer having electrical leads configured to acquire EEG signals from the subject, the flexible circuit layer having a shielding layer configured to substantially reduce a coupling of the plurality of electrical leads to external sources of noise, and a holder to which the flexible circuit layer is secured. The system also includes an electronics module removably coupled to the holder and configured to engage electrical contacts on the flexible circuit layer, the module including a front-end module configured to perform an active noise cancellation process on the acquired EEG signals and generate digitized data using noise cancelled signals, and a processor configured to transmit the digitized data using a wireless communication module.
    Type: Application
    Filed: September 2, 2016
    Publication date: August 30, 2018
    Inventors: Patrick L. Purdon, Michael J. Prerau, Nathaniel M. Sims, Matthew Hickcox
  • Publication number: 20180177945
    Abstract: An infusion apparatus includes a housing and a chamber configured to be connected to the housing. The apparatus further includes a weight sensor coupled to a load connector connected to the housing and an optical sensor disposed in the housing. The weight sensor is configured to generate a first signal based on a measured weight of the fluid container attached to the housing in a weight-bearing configuration. The optical sensor is configured to generate a second signal based on detecting drops of the fluid traversing the chamber. The apparatus also includes a flow control mechanism to control a flow rate of the fluid into an outlet channel. The apparatus includes one or more processing devices configured to perform operations including transmitting a control signal to the flow control mechanism to adjust the flow rate.
    Type: Application
    Filed: November 12, 2015
    Publication date: June 28, 2018
    Inventors: Nathaniel M. Sims, Eric John Flachbart, Duane Edward Allen, Benjamin James Chomyn, Paul C. Henninge, Joseph Matthew Pasquence, Andrew W. Asack, Michael H. Wollowitz, Rolf E. Zuk
  • Publication number: 20170326293
    Abstract: An infusion apparatus for use with a syringe includes a housing enclosing a drivetrain. The drivetrain includes a pinion, spur gears, and a worm gear. One spur gear is arranged to engage with the pinion and another spur gear is arranged to engage with the worm gear. The housing also includes a carriage movable with respect to the housing. A frame on the carriage receives a syringe plunger. A rack on the carriage engages with the pinion to move the carriage parallel to a longitudinal axis of the housing. A pusher assembly of the housing securely engages with the syringe plunger. A motor in the apparatus rotates a worm drive that meshes with the worm gear to drive the drivetrain. A trigger of the apparatus is configured to disengage the worm drive from the worm gear to allow free movement of the carriage relative to the housing.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 16, 2017
    Inventors: Nathaniel M. Sims, Eric John Flachbart, Duane Edward Allen, Benjamin James Chomyn, Paul C. Henninge, Joseph Matthew Pasquence, Andrew W. Asack, Michael H. Wollowitz, Rolf E. Zuk
  • Patent number: 9764087
    Abstract: Systems for predicting a drug delivery profile as described herein include at least one drug pump and/or a controllable valve that produce a drug flow and dispense at least a first drug. The system also includes at least one carrier fluid pump and/or another controllable valve that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: September 19, 2017
    Assignees: The General Hospital Corporation, Steward St. Elizabeth's Medical Center of Boston, Inc.
    Inventors: Robert A. Peterfreund, Michael Parker, Nathaniel M. Sims, Mark A. Lovich, Harold J. DeMonaco
  • Patent number: 9687195
    Abstract: A wearable platform embodied in a belt or patch provides physiological monitoring of soldiers during field operations or trauma victims at accident sites and makes health state assessments. The platform includes sensors for heart rate, body motion, respiration rate and intensity, and temperature and further contains a microprocessor and short range transmitter. An analog circuit running an algorithm obtains the R-wave period from the EKG signal and produces electrical pulses with the period between pulses corresponding to the R-wave period. A rule based processing engine having an evaluation algorithm is capable of making a medical evaluation of subject condition and determines a confidence level for the evaluation. The rules are subject to variation depending upon the subject population. The information is communicated wirelessly to a local hub for relay to a remote monitor.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: June 27, 2017
    Assignees: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Nathaniel M. Sims, Nhedti Colquitt, Michael Wollowitz, Matt Hickcox, Michael Dempsey, Reed J. Hoyt, Mark J. Buller, John S. Ames
  • Publication number: 20160055317
    Abstract: Disclosed are systems and methods for enabling transfer of a drug from a first drug container to a second drug container including a drug identification component that recognizes a first drug container to retrieve drug identifying data for the drug, a storage medium that stores a site-specific database comprising attributes and associated values for a set of drugs including the drug in the first drug container, a processor that obtains the drug identifying data and the attributes and associated values for the drug and produces information about the drug using the drug identifying data and the attributes and associated values, a rules engine that applies one or more rules to the information about the drug to generate drug handling information, and an output unit that outputs markings comprising the drug handling information in human-readable or machine-readable form, or both, to be associated with the second container.
    Type: Application
    Filed: November 5, 2015
    Publication date: February 25, 2016
    Inventors: Wilton C. Levine, James Kenneth Davison, Michael Dempsey, Kimberly Donovan, William D. Driscoll, Gayle A. Fishman, Nathaniel M. Sims
  • Publication number: 20150356253
    Abstract: Disclosed herein are methods, apparatus and computer program products for a customizable and contextually relevant medical system with automatic reconfiguration and data binding. Some embodiments relate to an enterprise digital assistant capable of changing its functionality based on context and binding medical information associated with one medical entity, for example, a care giver, patient or medical system/device, to medical information associated with another medical entity. Other embodiments relate to a method for automatically reconfiguring an enterprise digital assistant based on context and performing contextually relevant data binding. In this regard, the method provides a module for processing medical data from a plurality of medical entities and transmitting the data to one or more clinical information systems.
    Type: Application
    Filed: August 7, 2015
    Publication date: December 10, 2015
    Inventors: Nathaniel M. Sims, Michael Dempsey, Kimberly Donovan
  • Publication number: 20140303591
    Abstract: Systems for predicting a drug delivery profile as described herein include at least one drug pump and/or a controllable valve that produce a drug flow. The drug pump and/or controllable valve dispense at least a first drug. The system also includes at least one carrier fluid pump and/or another controllable valve that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.
    Type: Application
    Filed: November 20, 2012
    Publication date: October 9, 2014
    Inventors: Robert A. Peterfreund, Michael Parker, Nathaniel M. Sims, Mark A. Lovich, Harold J. DeMonaco
  • Publication number: 20140249430
    Abstract: A wearable platform embodied in a belt or patch provides physiological monitoring of soldiers during field operations or trauma victims at accident sites and makes health state assessments. The platform includes sensors for heart rate, body motion, respiration rate and intensity, and temperature and further contains a microprocessor and short range transmitter. An analog circuit running an algorithm obtains the R-wave period from the EKG signal and produces electrical pulses with the period between pulses corresponding to the R-wave period. A rule based processing engine having an evaluation algorithm is capable of making a medical evaluation of subject condition and determines a confidence level for the evaluation. The rules are subject to variation depending upon the subject population. The information is communicated wirelessly to a local hub for relay to a remote monitor.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 4, 2014
    Applicants: Goverment of the United States, as Represented by the Secretary of the Army, The General Hospital Corporation
    Inventors: Nathaniel M. SIMS, Nhedti COLQUITT, Michael WOLLOWITZ, Matt HICKCOX, Michael DEMPSEY, Reed J. HOYT, Mark J. BULLER, John S. AMES
  • Publication number: 20140136229
    Abstract: Disclosed are systems and methods for enabling transfer of a drug from a first drug container to a second drug container including a drug identification component that recognizes a first drug container to retrieve drug identifying data for the drug, a storage medium that stores a site-specific database comprising attributes and associated values for a set of drugs including the drug in the first drug container, a processor that obtains the drug identifying data and the attributes and associated values for the drug and produces information about the drug using the drug identifying data and the attributes and associated values, a rules engine that applies one or more rules to the information about the drug to generate drug handling information, and an output unit that outputs markings comprising the drug handling information in human-readable or machine-readable form, or both, to be associated with the second container.
    Type: Application
    Filed: January 20, 2014
    Publication date: May 15, 2014
    Applicant: The General Hospital Corporation
    Inventors: Wilton C. Levine, James Kenneth Davison, Michael Dempsey, Kimberly Donovan, William D. Driscoll, Gayle A. Fishman, Nathaniel M. Sims
  • Patent number: 8639525
    Abstract: Disclosed are systems and methods for enabling transfer of a drug from a first drug container to a second drug container including a drug identification component that recognizes a first drug container to retrieve drug identifying data for the drug, a storage medium that stores a site-specific database comprising attributes and associated values for a set of drugs including the drug in the first drug container, a processor that obtains the drug identifying data and the attributes and associated values for the drug and produces information about the drug using the drug identifying data and the attributes and associated values, a rules engine that applies one or more rules to the information about the drug to generate drug handling information, and an output unit that outputs markings comprising the drug handling information in human-readable or machine-readable form, or both, to be associated with the second container.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: January 28, 2014
    Assignee: Codonics, Inc.
    Inventors: Wilton C. Levine, James Kenneth Davison, Michael Dempsey, Kimberly Donovan, William D. Driscoll, III, Gayle A. Fishman, Nathaniel M. Sims
  • Publication number: 20130218080
    Abstract: Systems for predicting a drug delivery profile as described herein include at least one drug pump that produces a drug flow. The drug pump dispenses at least a first drug. The system also includes at least one carrier fluid pump that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.
    Type: Application
    Filed: May 24, 2011
    Publication date: August 22, 2013
    Inventors: Robert A. Peterfreund, Michael Parker, Nathaniel M. Sims, Mark A. Lovich
  • Publication number: 20120330236
    Abstract: Various methods and devices for driving fluid from a syringe are provided. In one exemplary embodiment, a luer fitting for connecting a syringe barrel to a syringe driver is provided that includes a proximal female end including a socket adapted to be removably mated to a male luer fitting on the syringe barrel. The luer fitting further includes a distal end including a nozzle adapted to receive a fluid conduit. The distal end has a non-threaded axially-oriented annular socket formed therein for removably receiving a protrusion on the syringe driver.
    Type: Application
    Filed: July 27, 2012
    Publication date: December 27, 2012
    Applicant: THE GENERAL HOSPITAL CORPORATION d/b/a MASSACHUSETTS GENERAL HOSPITAL
    Inventors: Nathaniel M. Sims, Michael H. Wollowitz
  • Patent number: 8231576
    Abstract: Various methods and devices for driving fluid from a syringe are provided. In one exemplary embodiment, a syringe driver is provided having a frame that is adapted to seat a syringe, a driver that is slidably disposed within the frame and that is adapted to seat a plunger of a syringe, and a puller that is slidably disposed within the frame and that has a latch formed thereon for mating to an engagement element on the frame. The device can also include a force-delivery element, such as a constant force spring, that is coupled to and extends between the driver and the puller.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: July 31, 2012
    Assignee: The General Hospital Corporation
    Inventors: Nathaniel M. Sims, Michael H. Wollowitz
  • Publication number: 20110093279
    Abstract: Disclosed are systems and methods for enabling transfer of a drug from a first drug container to a second drug container including a drug identification component that recognizes a first drug container to retrieve drug identifying data for the drug, a storage medium that stores a site-specific database comprising attributes and associated values for a set of drugs including the drug in the first drug container, a processor that obtains the drug identifying data and the attributes and associated values for the drug and produces information about the drug using the drug identifying data and the attributes and associated values, a rules engine that applies one or more rules to the information about the drug to generate drug handling information, and an output unit that outputs markings comprising the drug handling information in human-readable or machine-readable form, or both, to be associated with the second container.
    Type: Application
    Filed: October 16, 2009
    Publication date: April 21, 2011
    Inventors: Wilton C. Levine, James Kenneth Davison, Michael Dempsey, Kimberly Donovan, William D. Driscoll, III, Gayle A. Fishman, Nathaniel M. Sims
  • Publication number: 20110092908
    Abstract: Various methods and devices for driving fluid from a syringe are provided. In one exemplary embodiment, a syringe driver is provided having a frame that is adapted to seat a syringe, a driver that is slidably disposed within the frame and that is adapted to seat a plunger of a syringe, and a puller that is slidably disposed within the frame and that has a latch formed thereon for mating to an engagement element on the frame. The device can also include a force-delivery element, such as a constant force spring, that is coupled to and extends between the driver and the puller.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 21, 2011
    Applicant: THE GENERAL HOSPITAL CORPORATION d/b/a MASSACHUSETTS GENERAL HOSPITAL
    Inventors: Nathaniel M. Sims, Michael H. Wollowitz
  • Patent number: 7867197
    Abstract: Various methods and devices for driving fluid from a syringe are provided. In one exemplary embodiment, a syringe driver is provided having a frame that is adapted to seat a syringe, a driver that is slidably disposed within the frame and that is adapted to seat a plunger of a syringe, and a puller that is slidably disposed within the frame and that has a latch formed thereon for mating to an engagement element on the frame. The device can also include a force-delivery element, such as a constant force spring, that is coupled to and extends between the driver and the puller.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: January 11, 2011
    Assignee: The General Hospital Corporation
    Inventors: Nathaniel M. Sims, Michael H. Wollowitz
  • Publication number: 20100332257
    Abstract: Disclosed herein are methods, apparatus and computer program products for a customizable and contextually relevant medical system with automatic reconfiguration and data binding. Some embodiments relate to an enterprise digital assistant capable of changing its functionality based on context and binding medical information associated with one medical entity, for example, a care giver, patient or medical system/device, to medical information associated with another medical entity. Other embodiments relate to a method for automatically reconfiguring an enterprise digital assistant based on context and performing contextually relevant data binding. In this regard, the method provides a module for processing medical data from a plurality of medical entities and transmitting the data to one or more clinical information systems.
    Type: Application
    Filed: October 10, 2008
    Publication date: December 30, 2010
    Inventors: Nathaniel M. Sims, Michael Dempsey, Kimberly Donovan
  • Patent number: 7471994
    Abstract: A system for creating a customized drug library for an electronically loadable drug infusion pump, the system including a drug library containing a plurality of drug entries, there being associated with each drug entry a set of associated drug delivery parameters and/or drug delivery protocols for configuring the drug infusion pump; a tool for selecting a set of drug entries from among the plurality of drug entries in said drug library; a tool for adding the selected drug entries along with the sets of drug delivery information associated therewith to a customized library; and a loading tool for causing the system to electronically load the customized library into the drug infusion pump.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: December 30, 2008
    Assignees: The General Hospital Corporation, Baxter International Inc.
    Inventors: Alan D. Ford, Nathaniel M. Sims, Marc A. Mandro
  • Publication number: 20020077852
    Abstract: A system for creating a customized drug library for an electronically loadable drug infusion pump, the system including a drug library containing a plurality of drug entries, there being associated with each drug entry a set of associated drug delivery parameters and/or drug delivery protocols for configuring the drug infusion pump; a tool for selecting a set of drug entries from among the plurality of drug entries in said drug library; a tool for adding the selected drug entries along with the sets of drug delivery information associated therewith to a customized library; and a loading tool for causing the system to electronically load the customized library into the drug infusion pump.
    Type: Application
    Filed: June 8, 2001
    Publication date: June 20, 2002
    Applicant: The General Hospital, Massachusetts corporation
    Inventors: Alan D. Ford, Nathaniel M. Sims, Marc A. Mandro