Patents by Inventor Nathaniel Ross Liddy

Nathaniel Ross Liddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T CELL RECEPTORS
    Publication number: 20120027739
    Abstract: A T cell receptor (TCR) having the property of binding to EVDPIGHLY HLA-A1 complex and comprising a specified wild type TCR which has specific mutations in the TCR alpha variable domain and/or the TCR beta variable domain to increase affinity. Such TCRs are useful for adoptive therapy.
    Type: Application
    Filed: August 4, 2010
    Publication date: February 2, 2012
    Applicant: Immunocore Limited
    Inventors: Bent Karsten Jakobsen, Nathaniel Ross Liddy
  • High Affinity Melan-A T Cell Receptors
    Publication number: 20080292549
    Abstract: The present invention provides TCRs having an affinity (KD) of less than or equal to 3 ?M, and/or an off-rate (koff) of 1×10?3 S?1 or slower, for the AAGIGILTV-HLA-A*0201 complex. Such TCRs are useful, either alone or associated with a therapeutic agent, for targeting cancer cells presenting that complex.
    Type: Application
    Filed: May 31, 2006
    Publication date: November 27, 2008
    Applicant: MEDIGENE LIMITED
    Inventors: Bent Karsten Jakobsen, Nathaniel Ross Liddy