Abstract: The present invention relates to a method for producing a culture medium-derived component or a crystallized culture medium using a PCA (Precipitation with Compressed Fluid Anti-solvent) drying process, a method for restoring chondrocytes using the culture medium-derived component or the crystallized culture medium prepared by way of the above method, a method for treating a subject having osteoarthritis by way of the method for restoring chondrocytes using the culture medium-derived component or the crystallized culture medium, a method for treating a subject having osteoarthritis using the culture medium-derived component or the crystallized culture medium, and the use of the culture medium-derived component or the crystallized culture medium for the treatment of osteoarthritis.

Abstract: According to one aspect of the present invention, there is provided a method for preparing a hydrogel, comprising: bringing into contact with each other (i) a positively charged composition comprising a positively charged polymer or a derivative thereof, and a first temperature-sensitive polymer; and (ii) a negatively charged composition comprising a negatively charged polymer and a second temperature-sensitive polymer.

Abstract: The present invention relates to a method of co-incubating multiple cells. According to the present invention, an interaction between the multiple cells is facilitated without causing cytotoxicity, and a single cell can be separated without damage to the cells. Therefore, the present invention can be applied to a study of regeneration on various types of tissue cells.

Abstract: The present invention relates to a bone-specific complex and can solve the stability problem of a viral carrier and foreign gene expression technology by inducing overexpression of targeted endogenous genes without the introduction of foreign genes. The present invention allows enhanced efficiency by stably labeling a targeted object and accurately confirming whether or not application is carried out to the targeted object, and thus can efficiently be applied to the field of developing a new protein-based drug technology requiring particular cell transformation such as osteoporosis and direct transdifferentiation.