Patents by Inventor Nathaniel Thomas

Nathaniel Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250032007
    Abstract: Systems and methods are provided to provide guidance to a user regarding management of a physiologic condition such as diabetes. The determination may be based upon a patient glucose concentration level. The glucose concentration level may be provided to a stored model to determine a state. The guidance may be determined based at least in part on the determined state.
    Type: Application
    Filed: October 11, 2024
    Publication date: January 30, 2025
    Inventors: Alexandra Elena CONSTANTIN, Scott M. BELLIVEAU, Naresh C. BHAVARAJU, Jennifer D. BLACKWELL, Eric S. COHEN, Basab DATTARAY, Anna Leigh DAVIS, Rian W. DRAEGER, Arturo GARCIA, John Michael GRAY, Hari HAMPAPURAM, Nathaniel David HEINTZMANN, Lauren Hruby JEPSON, Matthew Lawrence JOHNSON, Apurv Ullas KAMATH, Katherine Yerre KOEHLER, Phil MAYOU, Patrick Wile MCBRIDE, Michael Robert MENSINGER, Sumitaka MIKAMI, Andrew Attila PAL, Nicholas POLYTARIDIS, Philip Thomas PUPA, Eli REIHMAN, Peter C. SIMPSON, Tomas C. WALKER, Daniel Justin WIEDEBACK, Subrai Girish PAI, Matthew T. VOGEL
  • Publication number: 20240368096
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: February 21, 2024
    Publication date: November 7, 2024
    Inventors: Samuel BARTLETT, Joseph D. PANARESE, Sourav GHORAI, Nathaniel Thomas KENTON, Sean RAFFERTY, Jonathan THIELMAN, Peilin XU, Bin WANG, William CASSELS, Scott MITCHELL, Yat Sun OR
  • Publication number: 20240325409
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: February 26, 2024
    Publication date: October 3, 2024
    Inventors: Sean RAFFERTY, Sourav GHORAI, Nathaniel Thomas KENTON, Peilin XU, Samuel BARTLETT, Scott MITCHELL, Joseph D. PANARESE, Yat Sun OR
  • Publication number: 20240262828
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: December 18, 2023
    Publication date: August 8, 2024
    Inventors: Joseph D. PANARESE, Dexter DAVIS, Samuel BARTLETT, Katherine CHONG, Nathaniel Thomas KENTON, Yat Sun OR
  • Publication number: 20240140922
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: August 22, 2023
    Publication date: May 2, 2024
    Inventors: Samuel Bartlett, Joseph D. Panarese, Sourav Ghorai, Nathaniel Thomas Kenton, Sean Rafferty, Jonathan Thielman, Peilin Xu, Bin Wang, William Cassels, Scott Mitchell, Yat Sun Or
  • Patent number: 11969188
    Abstract: Devices used to deploy transvascular medical device systems and methods for using such devices are described in this document. For example, this document describes dilating introducer devices used for the percutaneous vascular deployment of catheter-based medical devices such as structural heart medical devices. Such dilating introducer devices can facilitate the percutaneous vascular deployment of catheter-based medical devices without an additional introducer sheath.
    Type: Grant
    Filed: September 18, 2023
    Date of Patent: April 30, 2024
    Assignee: Laplace Interventional Inc.
    Inventors: Nathaniel Thomas Smith, Gunnar Paul Askegaard, Lucas Tradd Schneider, Ramji Iyer
  • Patent number: 11954317
    Abstract: Systems and methods for providing for visualization and analysis of geospatial data are described. An example method includes automatically generating a first map comprising a plurality of layers that each comprise part of the input data, providing a graphical user interface for receiving at least one selection from the user of one or more of the plurality of layers of the first map for display and an indication that the user has zoomed in on the first map to a first area featuring a symbol corresponding to an item of interest, and automatically generating, based on bounds of the dataset, a second map showing a second area of a bounding shape selected to fit the data related to the item of interest.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: April 9, 2024
    Assignee: Elasticsearch B.V.
    Inventors: Nathaniel Thomas Reese, Nicholas W. Knize, Thomas Raphaël Gentiel Neirynck
  • Publication number: 20240101533
    Abstract: The present disclosure relates to methods and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.
    Type: Application
    Filed: June 5, 2023
    Publication date: March 28, 2024
    Inventors: Kevin McCormack Allan, Amanda Lynn Vandehey, Gediminas Brizgys, Sachin Dhar, Ian James Doxsee, Alex Goldberg, Lars V. Heumann, Zilin Huang, Nathaniel Thomas Kadunce, Shahrokh Kazerani, Willard Lew, Vinh Xuan Ngo, Brian Michael O`Keefe, Trevor James Rainey, Benjamin James Roberts, Bing Shi, Dietrich P. Steinhuebel, Winston C. Tse, Anna Michelle Wagner, Xianghong Wang, Scott Alan Wolckenhauer, Chloe Yuyi Wong, Jennifer R. Zhang
  • Patent number: 11849795
    Abstract: An upper for an article of footwear and a method of manufacturing the upper for an article of footwear are disclosed. The upper incorporates a textile element with edges that are joined together to define at least a portion of a void for receiving a foot. The joined edges form a plurality of seams within the textile element, including a longitudinal seam extending on the lower region of the upper from a heel region to a forefoot region. Various warp knitting or weft knitting processes, including circular knitting, may be utilized to form the textile element.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: December 26, 2023
    Assignee: NIKE, Inc.
    Inventors: Bhupesh Dua, Edward Nathaniel Thomas
  • Patent number: 11802125
    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: October 31, 2023
    Inventors: Joseph D. Panarese, Dexter Davis, Nathaniel Thomas Kenton, Samuel Bartlett, Yat Sun Or
  • Patent number: 11757110
    Abstract: A method for operating a fuel cell system comprising a fuel cell assembly of a plurality of fuel cells configured to generate electrical power from a fuel flow and an oxidant flow to the plurality of fuel cells, the fuel cell assembly arranged in combination with a coolant storage module configured to supply the fuel cell assembly with a flow of coolant, the method performed when the temperature of the coolant in the coolant storage module is below a coolant temperature threshold and comprises; a first phase performed prior to activation of a coolant pump configured to deliver coolant from the coolant storage module to the fuel cell assembly and a second phase performed after activation of the coolant pump.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: September 12, 2023
    Assignee: Intelligent Energy Limited
    Inventors: Shahin Moghimi, Nathaniel Thomas Palmer, Pratap Rama, Alex Mark Thirkell
  • Publication number: 20230103494
    Abstract: The present invention discloses compounds of Formula (Ia), and pharmaceutically acceptable salts, thereof: which inhibit coronavirus replication activity. The invention further relates to pharmaceutical compositions comprising a compound of Formula (Ia) or a pharmaceutically acceptable salt thereof, and methods of treating or preventing a coronavirus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (Ia) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 22, 2021
    Publication date: April 6, 2023
    Inventors: Guoqiang Wang, Ruichao Shen, Yong He, Jun Ma, Xuechao Xing, Hui Cao, Xuri Gao, Xiaowen Peng, Jiang Long, Wei Li, Jiajun Zhang, Joseph D. Panarese, Nathaniel Thomas Kenton, Samuel Bartlett, Yat Sun Or
  • Publication number: 20230048298
    Abstract: Systems and methods for providing for visualization and analysis of geospatial data are described. An example method includes automatically generating a first map comprising a plurality of layers that each comprise part of the input data, providing a graphical user interface for receiving at least one selection from the user of one or more of the plurality of layers of the first map for display and an indication that the user has zoomed in on the first map to a first area featuring a symbol corresponding to an item of interest, and automatically generating, based on bounds of the dataset, a second map showing a second area of a bounding shape selected to fit the data related to the item of interest.
    Type: Application
    Filed: July 22, 2022
    Publication date: February 16, 2023
    Inventors: Nathaniel Thomas Reese, Nicholas W. Knize, Thomas Raphaël Gentiel Neirynck
  • Publication number: 20230024272
    Abstract: Embodiments of the invention disclosed relate to systems and methods for facilitating the development of an athlete in a given sport. In one embodiment, a system can include one or more computing devices communicating via a computer network to receive input associated with Skill Scores and to compute and store an Athlete Development Rating (ADR) based at least on said input. In one embodiment, the ADR is based on a composite score of one or more Skills Scores and/or one or more Skill Group Scores. In certain embodiments, Skill Scores are associated with date data to provide a historical view of the athlete's development. In some embodiments, Skill Scores can be based on quantitative, objective assessments and/or qualitative, subjective expert assessments. Program modules can be configured to display historical ADR data, Skill Scores, and/or Skill Group Scores.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 26, 2023
    Inventor: Russell Nathaniel Thomas, JR.
  • Patent number: 11397516
    Abstract: Systems and methods for providing for visualization and analysis of geospatial data are described. An example method includes receiving input data comprising at least geospatial data; automatically generating a first map comprising a plurality of layers, each comprising part of the input data; providing a graphical user interface (GUI) for receiving selection(s) from a user of one or more layers of the first map for display; automatically generating a second map based on the selection(s); and causing display of the second map on a client device. Input data may originate from several data sources and include documents from a search and analytics engine. The map's visual properties are configurable based on user input via the GUI or a configuration. The example method combines server-side clustering and client-side symbolization to seamlessly create maps showing data of arbitrary size. The example method provides real-time full-text searching of map data of any size.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: July 26, 2022
    Assignee: Elasticsearch B.V.
    Inventors: Nathaniel Thomas Reese, Nicholas W. Knize, Thomas Neirynck
  • Patent number: 11358953
    Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, thereof: which inhibit coronavirus replication activity. The invention further relates to pharmaceutical compositions comprising a compound of Formula (I) or a pharmaceutically acceptable slat thereof, and methods of treating or preventing a coronavirus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: June 14, 2022
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Joseph D. Panarese, Dexter Davis, Nathaniel Thomas Kenton, Samuel Bartlett, Sean M. Rafferty, Yat Sun Or
  • Patent number: 11362345
    Abstract: Disclosed is a cooling module for use in a fuel cell system, the module includes a tank configured to receive a coolant therein, a coolant, a pump in fluid communication with the coolant in the tank and the fuel cell system, the pump being configured to transport the coolant to the fuel cell system, a heating element within the coolant in the tank, the heating element configured to heat the coolant, and at least one sensor in signal communication with a controller and in fluid communication with the tank. The sensor is configured to detect a change corresponding to the presence or absence of sufficient liquid coolant to initiate said pump, and the controller processes sensor data and is configured to actuate the pump.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: June 14, 2022
    Assignee: Intelligent Energy Limited
    Inventors: Pratap Rama, Nathaniel Thomas Palmer, Sophie Charlotte Harris, David James Grimwade, Prajwal Nirwan
  • Publication number: 20220073499
    Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, thereof: which inhibit coronavirus replication activity. The invention further relates to pharmaceutical compositions comprising a compound of Formula (I) or a pharmaceutically acceptable slat thereof, and methods of treating or preventing a coronavirus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 9, 2021
    Publication date: March 10, 2022
    Inventors: Joseph D. Panarese, Dexter Davis, Nathaniel Thomas Kenton, Samuel Bartlett, Sean M. Rafferty, Yat Sun Or
  • Publication number: 20220048944
    Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, thereof: which inhibit coronavirus replication activity. The invention further relates to pharmaceutical compositions comprising a compound of Formula (I) or a pharmaceutically acceptable slat thereof, and methods of treating or preventing a coronavirus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 12, 2021
    Publication date: February 17, 2022
    Inventors: Joseph D. Panarese, Dexter Davis, Nathaniel Thomas Kenton, Samuel Bartlett, Sean M. Rafferty, Yat Sun Or
  • Publication number: 20220041652
    Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, thereof: which inhibit coronavirus replication activity. The invention further relates to pharmaceutical compositions comprising a compound of Formula (I) or a pharmaceutically acceptable slat thereof, and methods of treating or preventing a coronavirus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 10, 2022
    Inventors: Joseph D. Panarese, Dexter Davis, Nathaniel Thomas Kenton, Samuel Bartlett, Sean M. Rafferty, Yat Sun Or