Abstract: A therapeutic agent for treating at least one disease selected from the group consisting of inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases, comprising: at least one selected from the group consisting of a compound represented by the following general formula (1) and pharmacologically acceptable salts thereof as an active ingredient. [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group.

Abstract: A therapeutic agent for treating at least one disease selected from the group consisting of inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases, comprising: at least one selected from the group consisting of a compound represented by the following general formula (1) and pharmacologically acceptable salts thereof as an active ingredient. [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group.

Abstract: A compound represented by the general formula (1) below or a pharmacologically acceptable salt thereof: [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group].

Abstract: A compound represented by the general formula (1) below or a pharmacologically acceptable salt thereof: [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: —CH2—, —CH2—CH2—, —CH2—CH2—CH2—, or —CH2—O—CH2—; and Z represents a hydrogen atom or a hydroxyl group.

Abstract: The security of an authentication system using a one-time password is increased, a shift from an authentication system using a fixed password is simplified, and a range of use is increased. An authentication system wherein a one-time password is synchronized with time, or an authentication system wherein a one-time password is synchronized with the number of online service authentication requests, is provided. When a one-time password client 9 downloads a one-time password for online service authentication from a one-time password server 2, current time information or a current value of the number of online service authentication requests is made to coincide between the client and server, and an online service authentication request is authenticated as long as the downloaded one-time password for online service authentication is valid. The one-time password may also be synchronized with service usage details contained in the online service authentication request.

Abstract: The security of an authentication system using a one-time password is increased, a shift from an authentication system using a fixed password is simplified, and a range of use is increased. An authentication system wherein a one-time password is synchronized with time, or an authentication system wherein a one-time password is synchronized with the number of online service authentication requests, is provided. When a one-time password client 9 downloads a one-time password for online service authentication from a one-time password server 2, current time information or a current value of the number of online service authentication requests is made to coincide between the client and server, and an online service authentication request is authenticated as long as the downloaded one-time password for online service authentication is valid. The one-time password may also be synchronized with service usage details contained in the online service authentication request.

Abstract: A verification system in which a client terminal can safely receive online service from an online service server. The verification system includes an online service server, an information terminal device for receiving online service, an OTP server for performing a process involving login verification of the information terminal device and verification of online service transaction contents, and a portable terminal device that displays an OTP used for login verification and transaction contents verification. The portable terminal device includes means for transmitting, to the OTP server, separate acquisition requests for a login-verifying OTP and a transaction-contents-verifying OTP that the information terminal device requires when receiving online service from the online service server, receiving a login verifying OTP and a transaction contents verifying OTP from the OTP server, and displaying them.