Abstract: A sole structure for a shoe includes an upper wall portion disposed on the upper side, a lower wall portion disposed below and away from the upper wall portion, and a sidewall portion that is disposed between the upper wall portion and the lower wall portion and that is elastically deformable in the vertical direction. The upper and lower wall portions and the sidewall portion are formed of resin-made wall-shaped members. A three-dimensional elastic fiber structure formed of resin fibers is provided in the interior region between the upper wall portion and the lower wall portion. The interior region includes a hollow portion that is in contact with the three-dimensional elastic fiber structure via a partition wall formed of a resin-made wall-shaped member.

Abstract: A method for manufacturing a sole of an article of footwear uses an additive manufacturing through a 3D printer. The sole body 20 has an inclined surface or a curved surface BL0 to be a supported surface by a support at a toe spring portion Tu/a heel-up portion Hu/a side-up portion Su. The method includes a forming process in which a plurality of pillar-shaped supports 20sp that extend from the inclined/curved surface BL0 toward the bottom surface of the sole at the time of forming the sole through the 3D printer, and a cutting process to cut at least a portion of the pillar-shaped supports 20sp.

Abstract: A sole structure includes a sole body. The sole body is a resin-made box-shaped member with a predetermined thickness and an interior space that is defined by an upper wall portion disposed on an upper side, a lower wall portion disposed on a lower side and spaced apart from the upper wall portion, and a pair of sidewall portions disposed between and interconnecting the upper wall portion and the lower wall portion in a heel region or a forefoot region that respectively corresponds to a heel portion or a forefoot portion of a foot of a shoe wearer. The sidewall portions are elastically deformable in a vertical direction and have a plurality of solid or hollow ribs that extend in a substantially vertical direction between the upper wall portion and the lower wall portion.

Abstract: A glass structure includes: a plurality of glass particles, each of the glass particles including SiO2, CaO and P2O5; and a bonding portion that bonds the glass particles to one another and contains hydroxyapatite, wherein at least a part of the hydroxyapatite is crystalline in the bonding portion, and wherein a porosity of the glass structure is 15% or less. A method for producing the glass structure includes: preparing a mixture by mixing a plurality of glass particles and an aqueous solution with each other, each of the glass particles including SiO2, CaO and P2O5, and the aqueous solution including calcium and phosphorus and having pH of 4.0 or more; and heating and pressurizing the mixture.

Abstract: The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.

Abstract: A support is configured such that a bulge is allowed to deform toward a deformation space due to the deformation space when the deformation space is in an open state, and that the bulge is allowed to deform upward and a buffer member is compressively deformed when the deformation space is in a closed state.

Abstract: Provided are a pretreatment method for detecting the number of cells containing Ki-67 protein-positive nuclei using Ki-67 antibody; a method for the detection; a kit to be used in the detection method; and determination of a therapy regimen using the aforesaid method. Attempts were made to activate Ki-67 antigen with the use of an enzyme having been considered as inappropriate for the activation thereof. By pretreating a sample with an enzyme not recognizing the epitope of MIB-1 (a rare cutter enzyme), the antigen activation of Ki-67 antigen was enhanced, while enhancing the antigenicity of other antigens including a cytokeratin too. As a result, a method for more objectively and more universally quantifying Ki-67-positive cells at higher reproducibility, said method comprising isolating cell nuclei from an FFPE section while enhancing the antigenicity and performing a reaction between Ki-67 protein, i.e., the target, existing in the cell nuclei with a fluorescently labeled antibody, has been completed.

Abstract: A medical image processing apparatus of an embodiment includes storage circuitry and setting-condition determining circuitry. The storage circuitry stores information about at least one of a position of a region of interest in a breast, a size of the region of interest, and a size of the breast, the information acquired based on an X-ray image of a breast of a subject. The setting-condition determining circuitry acquires a setting condition in ultrasonographic diagnosis for the breast based on the information about at least one of the position of the region of interest, the size of the region of interest, and the size of the breast.

Abstract: The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.

Abstract: The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.

Abstract: Disclosed is a test instrument for measuring an analyte in a liquid sample by a noble metal colloid aggregation measurement method. The test instrument involves a reaction chamber in which at least the liquid sample is to be reacted with a reagent, wherein the reagent is adhered on at least a part of a surface constituting the reaction chamber in a dried state, and the reagent enables the measurement of the analyte by a noble metal colloid aggregation measurement method.

Abstract: An outsole includes: a first stud projecting downwards in a stationary manner in a vertical direction from a reference surface and having a first projection surface; and a second stud having a second projection surface. The second stud moves in the vertical direction so that, when an external force acts on the second projection surface, the outsole hollow is compressively transformed and the second projection surface comes close to the reference surface.

Abstract: Disclosed is a sole structure for shoes, which includes a lower midsole. The lower midsole includes a medial-side midsole portion which extends in a medial side portion of a heel region supporting a heel of a wearer's foot, and a lateral-side midsole portion which extends in a lateral side portion of the heel region, and which faces, and is spaced apart from, the medial-side midsole portion in a foot width direction. The lateral-side midsole portion includes supports which are arranged adjacent to each other in a longitudinal direction with a gap interposed therebetween and which support the wearer's heel, and a coupling portion which is provided in the gap, and couples the adjacent supports to each other to reduce displacement or twist in the foot width direction occurring between the adjacent supports.

Abstract: A support is configured such that a bulge is allowed to deform toward a deformation space due to the deformation space when the deformation space is in an open state, and that the bulge is allowed to deform upward and a buffer member is compressively deformed when the deformation space is in a closed state.

Abstract: An article of footwear having an adjustable heel mechanism is provided. The article of footwear can be capable of allowing a wearer to selectively alter the position of a portion of the heel portion of the article of footwear. In some embodiments, the article of footwear can have a sole, an upper attached to the sole and defining a void for a foot of a wearer, and a heel adjustment mechanism. In some embodiments, the heel adjustment mechanism may include a heel adjustment housing capable of moving with respect to the sole to modify the volume of the void created for the foot of a wearer.

Abstract: A sole includes a sole body supporting an entire planta of a wearer, lower protrusions protruding downward from a lower portion of the sole body toward the ground and spaced from each other, and upper protrusions protruding upward from an upper portion of the sole body toward a planta of a wearer, each of the upper protrusions being on the sole body and overlapping with an associated one of the lower protrusions. Each of the lower protrusions has, at its lower portion, a first region which makes contact with the ground, and each of the upper protrusions has, at its upper portion, a second region which makes contact with the planta of the wearer and is smaller than the first region.

Abstract: A medical information processing system according to an embodiment includes a storage, and processing circuitry. The storage stores therein a mammography image of a breast of a patient and information indicating an image taking direction of the mammography image. The processing circuitry sets a region of interest in the mammography image. The processing circuitry specifies position information of the region of interest in a schematic drawing that schematically expresses the breast, on the basis of position information of the region of interest in the mammography image and the information indicating the image taking direction. The processing circuitry outputs the position information of the region of interest in the schematic drawing.

Abstract: The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.