Patents by Inventor Natsuko Nishiyama

Natsuko Nishiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amphiphilic molecule, molecular assembly comprising the amphiphilic molecule, and use of the molecular assembly
    Patent number: 8241647
    Abstract: The present invention provides an amphiphilic molecule having a plurality of zwitterionic functional groups in its hydrophilic moiety and a molecular assembly comprising the amphiphilic molecule as a constituent lipid. The molecular assembly of the present invention forms a stable vesicular structure under a physiological pH environment to carry a substance of interest in the vesicular structure, and can release the substance of interest to the outside of the vesicular structure when it is deformed under an acidic pH environment. The molecular assembly of the present invention can be used as a carrier for a drug, a probe, a nucleic acid, a protein or the like.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: August 14, 2012
    Assignees: Waseda University, JCR Pharmaceuticals Co. Ltd.
    Inventors: Shinji Takeoka, Yosuke Obata, Shoji Tajima, Manabu Ito, Atsushi Mizuno, Natsuko Nishiyama, Yoshito Takeuchi
  • AMPHIPHILIC MOLECULE, MOLECULAR ASSEMBLY COMPRISING THE AMPHIPHILIC MOLECULE, AND USE OF THE MOLECULAR ASSEMBLY
    Publication number: 20100209458
    Abstract: The present invention provides an amphiphilic molecule having a plurality of zwitterionic functional groups in its hydrophilic moiety and a molecular assembly comprising the amphiphilic molecule as a constituent lipid. According to a preferred embodiment of the present invention, the molecular assembly of the present invention forms a stable vesicular structure under a physiological pH environment to carry a substance of interest in the vesicular structure, and can release the substance of interest to the outside of the vesicular structure when it is deformed under an acidic pH environment. The molecular assembly of the present invention can be used as a carrier for a drug, a probe, a nucleic acid, a protein or the like.
    Type: Application
    Filed: May 16, 2008
    Publication date: August 19, 2010
    Applicants: Waseda University, JCR Pharmaceuticals Co., Ltd.
    Inventors: Shinji Takeoka, Yosuke Obata, Shoji Tajima, Manabu Ito, Atsushi Mizuno, Natsuko Nishiyama, Yoshito Takeuchi