Abstract: The invention relates to a method for introducing biologically active substances into the brain, by the nasal introduction of a pharmaceutical composition consisting of biologically and therapeutically active substances together with membrane-active substances, hydrogen peroxide and nitrogen monoxide and their sources which remain in the nasal cavity in a disintegrated state, with only the pharmacologically active substances being transferred. The method is characterised in that the pharmaceutical composition is introduced nasally once or multiple times in complete or partial doses, that the time interval between introductions is between 3 and 180 seconds, preferably 60 seconds and that the drug dose is between 2 and 100 times smaller than the pharmaceutically predetermined dose.

Abstract: The invention relates to a pharmaceutical composition and arrangement thereof for nasal application. The aim of the invention is to increase the efficacy of drugs, metabolites and/or other previously described types of active ingredients that are indicated for the treatment of diseases and disorders of the central nervous system, to reduce the usually used dosage of the drugs, and to achieve a more rapid and prolonged effect. The pharmaceutical composition, composed of reciprocally related biologically active substances and substances that act on the nasal mucous membrane, is filled and stored in an aerosol in separate sealed packages and only combined upon use of the aerosol. The invention, which is straightforward to use, is intended for inpatient and private usage.

Abstract: The invention concerns a pharmaceutical product consisting of one or more standard active substances and/or of one or more standard metabolites acting on the central nervous system. Said active substances are added with substances acting on the nasal mucous membrane for endonasal administration.