Patents by Inventor Navdeep B. Malkar

Navdeep B. Malkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080234371
    Abstract: Stable and non-hygroscopic L-carnitine salts of organic acids are provided, each of which is present as a true complex salt, having the formula: wherein Z is acetate, propionate, or butyrate. In addition, processes for the preparation of these compounds are provided, together with the use of these compounds as a source of both L-carnitine and the calcium ion in nutrition or as a pharmaceutical active ingredient having therapeutic pharmacological activity.
    Type: Application
    Filed: March 19, 2007
    Publication date: September 25, 2008
    Inventors: Navdeep B. Malkar, Deanna J. Nelson
  • Publication number: 20080234514
    Abstract: The present invention relates to methods for preparing lithium valproate and administering this compound to a subject in need of treatment with lithium and/or valproate. Pharmaceutical compositions are also provided that are useful therapies for the treatment of neurological, immunological, and viral-mediated disorders in warm-blooded mammals.
    Type: Application
    Filed: April 15, 2008
    Publication date: September 25, 2008
    Inventors: Navdeep B. Malkar, Deanna Jean Nelson, Walter C. Holberg
  • Publication number: 20080234382
    Abstract: The present invention relates to methods for preparing lithium valproate and administering this compound to a subject in need of treatment with lithium and/or valproate. Pharmaceutical compositions are also provided that are useful therapies for the treatment of neurological, immunological, and viral-mediated disorders in warm-blooded mammals.
    Type: Application
    Filed: March 19, 2007
    Publication date: September 25, 2008
    Inventors: Navdeep B. Malkar, Deanna Jean Nelson, Walter C. Holberg
  • Publication number: 20040203081
    Abstract: Modified n atriuretic compounds and conjugates thereof are disclosed in the present invention. In particular, conjugated forms of hBNP are provided that include at least one modifying moiety attached thereto. The modified natriuretic compound conjugates retain activity for stimulating cGMP production, binding to NPR-A receptor, and in some embodiments an improved half-life in circulation as compared to unmodified counterpart natriuretic compounds. Oral, parenteral, subcutaneous, and intravenous forms of the compounds and conjugates may be prepared as treatments and/or therapies for heart conditions particularly congestive heart failure. Modifying moieties comprising oligomeric structures having a variety of lengths and configurations are also disclosed. Analogs of the n atriuretic compound are also disclosed, having an amino acid sequence that is other than the native sequence.
    Type: Application
    Filed: November 26, 2003
    Publication date: October 14, 2004
    Inventors: Kenneth D. James, Balasingham Radhakrishnan, Navdeep B. Malkar, Mark A. Miller, Nnochiri N. Ekwuribe