Patents by Inventor Naveed Shams

Naveed Shams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING AGE-RELATED MACULAR DEGENERATION
    Publication number: 20120009185
    Abstract: A method is provided for administering to a mammal suffering from, or at risk for, age-related macular degeneration.
    Type: Application
    Filed: September 19, 2011
    Publication date: January 12, 2012
    Applicant: Genentech, Inc.
    Inventor: Naveed Shams
  • COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF VEGF
    Publication number: 20100151007
    Abstract: Disclosed herein are siRNA compositions and methods useful for inhibiting expression of vascular endothelial growth factor (VEGF) isoforms. Such compositions and methods further involve siRNA capable of selectively targeting angiogenic VEGF isoforms while selectively sparing anti-angiogenic isoforms. Diseases which involve angiogenesis stimulated by overexpression of VEGF, such as diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering small interfering RNAs as disclosed.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 17, 2010
    Applicant: OPKO OPHTHALMICS, LLC
    Inventors: Phillip Frost, Nadine Dejneka, Ottrina S. Bond, Naveed Shams
  • METHOD FOR TREATING AGE-RELATED MACULAR DEGENERATION
    Publication number: 20100111963
    Abstract: A method is provided for administering to a mammal suffering from, or at risk for, age-related macular degeneration.
    Type: Application
    Filed: November 9, 2007
    Publication date: May 6, 2010
    Applicant: Genentech, Inc.
    Inventor: Naveed Shams
  • METHOD FOR TREATING INTRAOCULAR NEOVASCULAR DISEASES
    Publication number: 20070190058
    Abstract: A method is provided for administering to a mammal suffering from, or at risk for, an intraocular neovascular disorder with regular dosing of a therapeutically effective amount of VEGF antagonist, followed by less frequent dosing of a therapeutically effective amount of VEGF antagonist.
    Type: Application
    Filed: April 20, 2007
    Publication date: August 16, 2007
    Applicant: Genentech, Inc.
    Inventor: Naveed Shams
  • Ocular compositions that increases the activity of gelatinase a in ocular cells
    Publication number: 20060121090
    Abstract: Compositions capable of effecting a “pharmacological trabeculocanalotomy” in an eye by means of reducing juxtacanalicular meshwork as a barrier to outflow of aqueous. The small organic molecules increase Gelatinase A activity in ocular cells by increasing cell membrane expression of membrane-type matrix metalloproteinases (MT-MMPs) to increase aqueous outflow as a treatment for primary open angle glaucoma.
    Type: Application
    Filed: January 20, 2006
    Publication date: June 8, 2006
    Inventors: Bruce Pfeffer, Rosemarie Flick, Naveed Shams, Stephen Bartels