Abstract: Improved digital interfaces, graphical user interfaces, and alarms for analyte monitoring systems are provided. For example, disclosed herein are various embodiments of methods, systems, and interfaces for signal loss condition determination, Time-in-Ranges interfaces, GMI metrics, urgent low glucose alarms, alarm suppression features, alarm setup interfaces, and alarm unavailability detection features. In addition, various embodiments of interfaces for alarm logging and compatibility checking of an analyte monitoring software application are described. Also, various embodiments of interface enhancements are described, including an enhanced visibility mode, a voice accessibility mode, additional interfaces relating to user privacy, as well as caregiver alarms, among other embodiments.

Abstract: The present disclosure provides a method and apparatus for measuring or monitoring oxygenator blood volume of a treatment device such as an oxygenator by analyzing an indicator passing through the oxygenator blood volume. Measuring the oxygenator blood volume can be done externally of the vein or artery, or in tubing leading to a blood treatment system which carries the blood exterior of the body of the patient or within the body of the patient. The present system can also monitor tubing volume of flowing blood upstream or downstream of the blood treatment device. The present system thus provides for measuring the volume of an extracorporeal circuit and creates an opportunity to control circuit performance and give an early warning of clotting to improve the quality of a variety of extracorporeal procedures with the use of relatively simple technology.

Abstract: A system and accompanying method is provided for assessing a ratio of pulmonary to systemic blood flow in patients with a single-ventricle physiology (SVP). A compound dilution curve is recorded in an arterial vessel downstream of the pulmonary artery. A first component of the compound dilution curve is identified, wherein the first component is attributable to the indicator after passing through the single ventricle heart and directly into the arterial vessel A second component of the compound dilution curve is identified, wherein the second component is attributable to the indicator after passing from the single ventricle heart to the lungs, through the single ventricle heart and then to the arterial vessel downstream of the pulmonary artery. Based on the identified components, the pulmonary flow and systemic flow are assessed as corresponding to the identified first component and second component of the compound dilution curve.

Abstract: A method facilitating the measurement of hemodynamic parameters by injection of an indicator in an indicator dilution technique using an extracorporeal circuit connected to a patient, includes reducing a pressure spike associated with the introduction of the indicator into the extracorporeal circuit. The method diverts blood flow during an indicator introduction and then returns the diverted blood back into the extracorporeal circuit after the introduction is completed.

Abstract: A method and various devices are disclosed that facilitates the measurement of hemodynamic parameters by injection of an indicator in an indicator dilution technique using an extracorporeal circuit connected to a patient. Specifically, the invention deals with problems caused by the spike in pressure in an extracorporeal line that result from the injection of a bolus. The method and various devices provide for diversion of blood during an indictor injection process and then return of the diverted blood back into the system after the injection is completed. The variations of the invention use diversion lines, accommodating cases and other devices that are designed to accumulate blood displaced during injection and then returning the blood to the extracorporeal circuit after injection.

Abstract: A method and various devices are disclosed that facilitates the measurement of hemodynamic parameters by injection of an indicator in an indicator dilution technique using an extracorporeal circuit connected to a patient. Specifically, the invention deals with problems caused by the spike in pressure in an extracorporeal line that result from the injection of a bolus. The method and various devices provide for diversion of blood during an indictor injection process and then return of the diverted blood back into the system after the injection is completed. The variations of the invention use diversion lines, accommodating cases and other devices that are designed to accumulate blood displaced during injection and then returning the blood to the extracorporeal circuit after injection.

Abstract: A system and method is disclosed for measuring cardiac output. A closed fluid circuit is created between a patient's arterial cannula and venous cannula. A pump regulates flow through the closed fluid circuit. The closed fluid circuit includes at least one port for injection of an indicator. At least one sensor is attached to the closed fluid circuit for taking readings of a blood parameter after the indicator has flowed through the patients system at least once.