Patents by Inventor Navin Khanna

Navin Khanna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetravalent dengue vaccine
    Patent number: 11945842
    Abstract: The invention provides a recombinant polypeptide comprising the EDIII domain of each of Dengue virus serotype DENV-1, DENV-2, DENV-3, and DENV-4 linked to the N-terminal of HBsAg.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: April 2, 2024
    Assignee: INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
    Inventors: Navin Khanna, Viswanathan Ramasamy
  • USE OF COCCULUS HIRSUTUS EXTRACT FOR TREATING DENGUE
    Publication number: 20220023372
    Abstract: The present invention relates to a composite extract of Cocculus hirsutus for use in the prevention and treatment of dengue and its pharmaceutical compositions. Further, it provides for a stable pharmaceutical composition comprising a therapeutically effective amount of the said extract for use in the treatment of dengue virus infection in a mammal. It also provides for a method for reducing viral load in the treatment of dengue virus infection by administering the composite extract or its pharmaceutical composition to a mammal in need thereof.
    Type: Application
    Filed: December 9, 2019
    Publication date: January 27, 2022
    Inventors: Kaushal NAYYAR, Upasana ARORA, Srinivas PALLA, Mohan PRASAD, Saravanan A, Sumit MADAN, Ruchi SOOD, Navin KHANNA, Ankur PODDAR, Rahul SHUKLA, Mudgal KOTHEKAR
  • TETRAVALENT DENGUE VACCINE
    Publication number: 20210122787
    Abstract: The invention provides a recombinant polypeptide comprising the EDIII domain of each of Dengue virus serotype DENV-1, DENV-2, DENV-3, and DENV-4 linked to the N-terminal of HBsAg.
    Type: Application
    Filed: October 22, 2020
    Publication date: April 29, 2021
    Inventors: Navin KHANNA, Viswanathan RAMASAMY
  • Tetravalent dengue vaccine
    Patent number: 10815280
    Abstract: The invention provides a recombinant polypeptide comprising the EDIII domain of each of Dengue virus serotype DENV-1, DENV-2, DENV-3, and DENV-4 linked to the N-terminal of HBsAg.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: October 27, 2020
    Assignee: INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
    Inventors: Navin Khanna, Viswanathan Ramasamy
  • TETRAVALENT DENGUE VACCINE
    Publication number: 20190194261
    Abstract: The invention provides a recombinant polypeptide comprising the EDIII domain of each of Dengue virus serotype DENV-1, DENV-2, DENV-3, and DENV-4 linked to the N-terminal of HBsAg.
    Type: Application
    Filed: December 6, 2018
    Publication date: June 27, 2019
    Inventors: Navin KHANNA, Viswanathan RAMASAMY
  • Tetravalent dengue vaccine
    Patent number: 10189877
    Abstract: The invention provides a recombinant polypeptide comprising the EDIII domain of each of Dengue virus serotype DENV-1, DENV-2, DENV-3, and DENV-4 linked to the N-terminal of HBsAg.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: January 29, 2019
    Assignee: International Centre for Genetic Engineering and Biotechnology
    Inventors: Navin Khanna, Viswanathan Ramasamy
  • ANTI DENGUE ACTIVITY OF CISSAMPELOS PAREIRA EXTRACTS
    Publication number: 20170281704
    Abstract: The present invention relates to the anti dengue activity of the cissampelos pareira extracts. Pharmaceutical compositions comprising extracts of cissampelos pareira and processes for the preparation of extracts of cissampelos pareira are also provided.
    Type: Application
    Filed: June 13, 2017
    Publication date: October 5, 2017
    Inventors: Pradip Kumar BHATNAGAR, Chandra Kant KATIYAR, Navin KHANNA, Dilip Jatashankar UPADHYAY, Sathyamangalam SWAMINATHAN, Kona SRINIVAS, Navin Kumar SHARMA, Anil KANAUJIA, Ruchi SOOD, Smita SINGHAL, Gyanesh SHUKLA, Rajeev DUGGAR, Pawan Kumar PAREEK, Yogendra SINGH, Seema KHAN, Rajendra RAUT
  • VACCINE
    Publication number: 20170240601
    Abstract: The invention provides a recombinant polypeptide comprising the EDIII domain of each of Dengue virus serotype DENV-1, DENV-2, DENV-3, and DENV-4 linked to the N-terminal of HBsAg.
    Type: Application
    Filed: August 21, 2015
    Publication date: August 24, 2017
    Inventors: Navin KHANNA, Viswanathan RAMASAMY
  • Anti dengue activity of extracts
    Patent number: 9707261
    Abstract: The present invention relates to the anti dengue activity of the cissampelos pareira extracts. Pharmaceutical compositions comprising extracts of cissampelos pareira and processes for the preparation of extracts of cissampelos pareira are also provided.
    Type: Grant
    Filed: January 23, 2010
    Date of Patent: July 18, 2017
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Pradip Kumar Bhatnagar, Chandra Kant Katiyar, Navin Khanna, Dilip Jatashankar Upadhyay, Sathyamangalam Swaminathan, Kona Srinivas, Navin Sharma, Anil Kanaujia, Ruchi Sood, Smita Singhal, Gyanesh Shukla, Rajeev Duggar, Pawan Kumar Pareek, Yogendra Singh, Seema Khan, Rajendra Raut
  • Humanized high affinity recombinant antibody against Hepatitis B surface antigen
    Patent number: 9567390
    Abstract: This invention relates to a high affinity recombinant humanized antibody fragment (scFv) specific for hepatitis B surface antigen having unique inter/intra chain bonding interaction because of 28 altered amino acid residues from the original mouse (5S) antibody and its chimeric Fab form, wherein fine tuning of the vernier zone residue makes it closer to the human sequence without any structural constraints.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: February 14, 2017
    Assignees: Department of Biotechnology, All India Institute of Medical Sciences, International Center for Genetic and Biotechnology
    Inventors: Subrata Sinha, Ashutosh Tiwari, Navin Khanna, Subrat K. Acharya
  • USE OF CISSAMPELOS PAREIRA EXTRACTS FOR TREATING DENGUE
    Publication number: 20160243182
    Abstract: The present invention relates to an extract of Cissampelos pareira, its pharmaceutical compositions, and its therapeutic use in the prevention and treatment of dengue. It also relates to processes for the preparation of these extracts.
    Type: Application
    Filed: March 22, 2016
    Publication date: August 25, 2016
    Inventors: Pradip Kumar BHATNAGAR, Chandra Kant KATIYAR, Navin KHANNA, Poornima TYAGI, Dilip Jatashankar UPADHYAY, Sathyamangalam SWAMINATHAN, Kona SRINIVAS, Navin Kumar SHARMA, Anil KANAUJIA, Ruchi SOOD, Tarani Kanta BARMAN, Smita SINGHAL, Gyanesh SHUKLA, Rajeev DUGGAR, Pawan Kumar PAREEK, Yatendra Kumar GUPTA, Yogendra SINGH, Seema KHAN, Rajendra RAUT, Raj Kumar SHIRUMALLA, Vijay KANOJE, Ramesh SUBBARAYAN, Ravisankar RAJERETHINAM
  • ANTI DENGUE ACTIVITY OF CISSAMPELOS PAREIRA EXTRACTS
    Publication number: 20120107424
    Abstract: The present invention relates to the anti dengue activity of the cissampelos pareira extracts. Pharmaceutical compositions comprising extracts of cissampelos pareira and processes for the preparation of extracts of cissampelos pareira are also provided.
    Type: Application
    Filed: January 23, 2010
    Publication date: May 3, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Pradip Kumar Bhatnagar, Chandra Kant Katiyar, Navin Khanna, Dilip Jatashankar Upadhyay, Sathyamangalam Swaminathan, Kona Srinivas, Navin Sharma, Anil Kanaujia, Ruchi Sood, Smita Singhal, Gyanesh Shukla, Rajeev Duggar, Pawan Kumar Pareek, Yogendra Singh, Seema Khan, Rajendra Raut
  • Humanized High Affinity Recombinant Antibody Against Hepatitis B Surface Antigen
    Publication number: 20110046354
    Abstract: This invention relates to a high affinity recombinant humanized antibody fragment (scFv) specific for hepatitis B surface antigen having unique inter/intra chain bonding interaction because of 28 altered amino acid residues from the original mouse (5S) antibody and its chimeric Fab form, wherein fine tuning of the vernier zone residue makes it closer to the human sequence without any structural constraints.
    Type: Application
    Filed: December 2, 2008
    Publication date: February 24, 2011
    Applicants: DEPARTMENT OF BIOTECHNOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, INTERNATIONAL CENTER FOR GENETIC AND BIOTECHNOLOGY
    Inventors: Subrata Sinha, Ashutosh Tiwari, Navin Khanna, Subrat K. Acharya
  • Recombinant Mouse-Human Chimeric Fab Against Hepatitis B Surface Antigen
    Publication number: 20100145025
    Abstract: The invention relates to a recombinant chimeric Fab antibody comprising a recombinant Fd and a recombinant chimeric light chain which binds to hepatitis B surface antigen with high affinity, generated by fusing variable region genes (VH and VL) of an anti-HBsAg mouse antibody 5S and constant region genes of human, CH1 region of human IgGI and the CL region of human kappa chain, wherein mouse VL and human CL are linked by overlap PCR to generate chimeric light chain and mouse VH and CH1 are linked by overlap PCR to generate chimeric Fd.
    Type: Application
    Filed: September 10, 2007
    Publication date: June 10, 2010
    Applicants: DEPARTMENT OF BIOTECHNOLOGY (DBT), ALL INDIA INSTITUTE OF MEDICAL SCIENCES (AIIMS)
    Inventors: Biplab Bose, Subrata Sinha, Navin Khanna, Subrat Kumar Acharya