Patents by Inventor Navjot Chahal

Navjot Chahal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biaryl ether sulfonamides and their use as therapeutic agents
    Patent number: 9481677
    Abstract: This invention is directed to biaryl ether sulfonamides, or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: November 1, 2016
    Assignee: XENON PHARMACEUTICALS INC.
    Inventors: Shifeng Liu, Thilo Focken, Navjot Chahal, Zaihui Zhang, Renata Marcella Oballa, Julia Fonarev
  • Biaryl ether sulfonamides and their use as therapeutic agents
    Patent number: 9365578
    Abstract: This invention is directed to biaryl ether sulfonamides, or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: June 14, 2016
    Assignee: Xenon Pharmaceuticals Inc.
    Inventors: Shifeng Liu, Thilo Focken, Navjot Chahal, Zaihui Zhang, Renata Marcella Oballa, Julia Fonarev
  • BIARYL ETHER SULFONAMIDES AND THEIR USE AS THERAPEUTIC AGENTS
    Publication number: 20140256736
    Abstract: This invention is directed to biaryl ether sulfonamides, or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
    Type: Application
    Filed: October 30, 2012
    Publication date: September 11, 2014
    Applicant: XENON PHARMACEUTICALS INC.
    Inventors: Shifeng Liu, Thilo Focken, Navjot Chahal, Zaihui Zhang, Renata Marcella Oballa, Julia Fonarev
  • BISARYLSULFONE AND DIALKYLARYLSULFONE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS
    Publication number: 20140113898
    Abstract: The invention relates to bisarylsulfone and dialkylarylsulfone compounds (e.g., compounds according to any of Formulas (I)-(IX) or compounds (1)-(227) of Tables 4 and 5) useful in treating conditions associated with calcium channel function, and particularly conditions associated with N-type calcium channel activity. The invention also relates to pharmaceutical compositions that include these bisarylsulfone compounds, as well methods for the treatment of conditions such as cardiovascular disease, epilepsy, cancer and pain.
    Type: Application
    Filed: November 4, 2011
    Publication date: April 24, 2014
    Applicant: Zalicus Pharmaceuticals Ltd.
    Inventors: Hassan A. Pajouhesh, Richard Holland, Yuanxi Zhou, Yongbao Zhu, Michael Edward Grimwood, Navjot Chahal
  • ARYL SULPHONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
    Publication number: 20120245137
    Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity, are disclosed. Specifically, a series of compounds containing aryl sulphone derivatives, as exemplified by Formula (I).
    Type: Application
    Filed: September 17, 2010
    Publication date: September 27, 2012
    Applicant: Zalicus Pharmaceuticals Ltd.
    Inventors: Hassan A. Pajouhesh, Robert Galemmo, JR., Richard Holland, Yuanxi Zhou, Yongbao Zhu, Eric Simonson, Navjot Chahal, Mike Grimwood
  • Bicyclic pyrimidine derivatives as calcium channel blockers
    Patent number: 8133998
    Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing thienopyrimidine or oxoquinazoline derivatives are disclosed of the general formula (1) or formula (2) where X is a linker and Y is an aromatic moiety or N(R5)(R6).
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: March 13, 2012
    Assignee: Zalicus Pharmaceuticals, Ltd.
    Inventors: Hassan Pajouhesh, Hossein Pajouhesh, Yanbing Ding, Jason Tan, Mike Grimwood, Francesco Belardetti, Ramesh Kaul, Richard Holland, Navjot Chahal
  • CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
    Publication number: 20090270394
    Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds of substituted or unsubstituted cyclylamine derivatives as shown in formulas (1).
    Type: Application
    Filed: April 28, 2009
    Publication date: October 29, 2009
    Inventors: Robert Galemmo, JR., Richard Holland, Gabriel Hum, Hossein Pajouhesh, Navjot Chahal, Mehran Seid-Bagherzadeh, Amy Girard
  • Amino acid derivatives as calcium channel blockers
    Publication number: 20090012010
    Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds containing both an amino acid functionality and multiple aromatic rings are disclosed of the general formula (1) where X is benzhydryl, or an aromatic or heteroaromatic ring.
    Type: Application
    Filed: May 14, 2008
    Publication date: January 8, 2009
    Applicant: Neuromed Phramaceuticals Ltd.
    Inventors: Robert Galemmo, JR., Richard Holland, Yanbing Ding, Lingyun Zhang, Gabriel Hum, Navjot Chahal, Joseph Duffy, Christian Stevenson, Andrew Ullman