Patents by Inventor Nayantara Kothari

Nayantara Kothari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210254062
    Abstract: Among other things, the present disclosure provides designed DMD oligonucleotides, compositions, and methods of use GC thereof. In some embodiments, the present disclosure provides technologies useful for repairing mutant DMD transcripts by skipping exon 51 or exon 53, so that the transcript can be translated into an internally truncated but at least partially functional Dystrophin protein variant. In some embodiments, the present disclosure provides technologies useful for modulating DMD transcript splicing. In some embodiments, provided technologies can alter splicing of a dystrophin (DMD) DMD transcript. In some embodiments, the present disclosure provides methods for treating diseases, such as muscular dystrophy, including but not limited to Duchenne muscular dystrophy, Becker's muscular dystrophy, etc.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 19, 2021
    Applicant: WAVE LIFE SCIENCES LTD.
    Inventors: Jason Jingxin Zhang, Chandra Vargeese, Naoki Iwamoto, Chikdu Shakti Shivalila, Nayantara Kothari, Ann Fiegen Durbin, Selvi Ramasamy, Pachamuthu Kandasamy, Jayakanthan Kumarasamy, Gopal Reddy Bommineni, Subramanian Marappan, Sethumadhavan Divakaramenon, David Charles Donnell Butler, Genliang Lu, Hailin Yang, Mamoru Shimizu, Prashant Monian
  • Patent number: 7884200
    Abstract: Provided herein are retroviral vectors for delivering interfering RNA into cells.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: February 8, 2011
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Dorre Grueneberg, Gerard Bain, Nayantara Kothari
  • Publication number: 20100028996
    Abstract: Provided herein are retroviral vectors for delivering interfering RNA into cells.
    Type: Application
    Filed: October 7, 2009
    Publication date: February 4, 2010
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Dorre GRUENEBERG, Gerard BAIN, Nayantara KOTHARI
  • Patent number: 7612195
    Abstract: Provided herein are retroviral vectors for delivering interfering RNA into cells.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: November 3, 2009
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Dorre Grueneberg, Gerard Bain, Nayantara Kothari
  • Publication number: 20060252153
    Abstract: Provided herein are retroviral vectors for delivering interfering RNA into cells.
    Type: Application
    Filed: October 21, 2004
    Publication date: November 9, 2006
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Dorre Grueneberg, Gerard Bain, Nayantara Kothari