Patents by Inventor Nazle Kuylen

Nazle Kuylen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and method for sample purification analysis
    Publication number: 20040132208
    Abstract: A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain the composition of interest while allowing smaller diameter interferants to pass through the membrane.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Applicant: Coulter International Corp.
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas, Carlos L. Aparicio, Michael L. Bell, Ravinder Gupta, Maria Elena Insausti, Jack D. McNeal, Paul W. Price, Sandra Socarras
  • Apparatus and method for biological sample preparation and analysis
    Publication number: 20040132198
    Abstract: A method for utilizing a filtration device for removing interferants from a sample containing cells in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain cells while allowing smaller diameter interferants to pass through the membrane. The apparatus also includes a means for of moving the sample from a sample container to and from the filtration device. The disclosed method utilizes a vacuum source to aspirate the sample into a lumen of the hollow fiber membrane so that the sample is retained in the lumen space until expelled into an analysis container or transported to an analyzer.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Applicant: Coulter International Corp.
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas
  • Apparatus for biological sample preparation and analysis
    Patent number: 6692702
    Abstract: A method for utilizing a filtration device for removing interferants from a sample containing cells in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain cells while allowing smaller diameter interferants to pass through the membrane. The apparatus also includes a means for of moving the sample from a sample container to and from the filtration device. The disclosed method utilizes a vacuum source to aspirate the sample into a lumen of the hollow fiber membrane so that the sample is retained in the lumen space until expelled into an analysis container or transported to an analyzer.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 17, 2004
    Assignee: Coulter International Corp.
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas
  • Apparatus and method for sample purification and analysis
    Patent number: 6692968
    Abstract: A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain the composition of interest while allowing smaller diameter interferants to pass through the membrane.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: February 17, 2004
    Assignee: Coulter International Corp.
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas, Carlos L. Aparicio, Michael L. Bell, Ravinder Gupta, Maria Elena Insausti, Jack D. McNeal, Paul W. Price, Sandra Socarras
  • Apparatus and method for sample purification and analysis
    Publication number: 20020123154
    Abstract: A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain the composition of interest while allowing smaller diameter interferants to pass through the membrane.
    Type: Application
    Filed: September 20, 2001
    Publication date: September 5, 2002
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas, Carlos L. Aparicio, Michael L. Bell, Ravinder Gupta, Maria Elena Insausti, Jack D. McNeal, Paul W. Price, Sandra Socarras
  • Identification of blast cells in a leukocyte cell preparation
    Patent number: 5905031
    Abstract: The necessity to detect blast cells in a patient sample to determine a treatment regime for leukemia has long been desired. The present invention relates to a method and assay reagents for identification of blast cells in a fluid sample. The method further enables the determination of the lineage of the blast cells. The new method provides a determination of blast cells in less time than prior art methods.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: May 18, 1999
    Assignee: Coulter International Corp.
    Inventors: Nazle Kuylen, Harold R. Crews, Gerald E. Jaffe, Maria Barcelon, Francis J. Lucas, Nancy M. Garcia