Patents by Inventor Nazreen Pancham

Nazreen Pancham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing a concentrate enriched in coagulation factors VII and VIIa
    Patent number: 4637932
    Abstract: There is disclosed an improved process for producing a concentrate containing coagulation factors VII and VIIa in relatively high purity by contacting an aqueous preparation containing factors VII and VIIa with a divalent metal salt adsorbent having selective affinity for calcium-binding coagulation factors and eluting the coagulation factors therefrom, and contacting the eluate with an anionic exchange resin and selectively eluting coagulation factors VII and VIIa therefrom by step or gradient elution techniques to obtain factors VII and VIIa in high yield, free of other coagulation factors and other proteins. In one embodiment of this invention Cohn Effluent I may be used as the source of factors VII and VIIa.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: January 20, 1987
    Assignee: Miles Laboratories, Inc.
    Inventor: Nazreen Pancham
  • Process for producing a lipoprotein-poor concentrate of coagulation factors VII and VIIa
    Patent number: 4473553
    Abstract: There is disclosed a process for producing coagulation factors VII and VIIa in relatively high purity by contacting an aqueous preparation containing factors VII and VIIa with a lipoprotein binding adsorbent and separating the coagulation factors and other proteins therefrom, contacting the resulting lipoprotein-poor solution with a divalent metal salt adsorbent having selective affinity for calcium-binding coagulation factors and eluting the coagulation factors therefrom, and contacting the eluate with an anionic exchange resin and selectively eluting coagulation factors VII and VIIa therefrom by step or gradient elution techniques to obtain factors VII and VIIa free of other coagulation factors and other proteins.
    Type: Grant
    Filed: December 2, 1983
    Date of Patent: September 25, 1984
    Assignee: Miles Laboratories, Inc.
    Inventors: Timothy R. Zuffi, Nazreen Pancham
  • Process for producing a concentrate of coagulation factors VII and VIIa
    Patent number: 4470969
    Abstract: There is disclosed a process for producing coagulation factors VII and VIIa in relatively high purity by contacting an aqueous preparation containing factors VII and VIIa with a protein precipitant and separating the coagulation factors and other proteins therefrom, contacting the resulting solution with a divalent metal salt adsorbent having selective affinity for calcium-binding coagulation factors and eluting the coagulation factors therefrom, and contacting the eluate with an anionic exchange resin and selectively eluting coagulation factors VII and VIIa therefrom by step or gradient elution techniques to obtain factors VII and VIIa free of other coagulation factors and other proteins.
    Type: Grant
    Filed: December 2, 1983
    Date of Patent: September 11, 1984
    Assignee: Miles Laboratories, Inc.
    Inventors: Nazreen Pancham, Timothy Zuffi