Abstract: The present disclosure relates methods for treating skin disorders caused by an immune deficiency with topical formulations comprising ethyl (R)-4-((1-(2-cyanoacetyl)piperidin-3-yl)amino)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (Compound I) or pharmaceutically acceptable derivative thereof. In particular, the topical formulations described herein may be used to treat atopic dermatitis, alopecia areata, or vitiligo.

Abstract: This application relates to a building energy analysis and management system for measurement and verification of building performance. The system can analyze, optimize, manage, maintain, trouble shoot, and/or modify building systems, such as HVAC systems, in connection with the building energy usage. Measurements may be gathered for one or more HVAC units coupled to pressure independent valves, and sent to one or more Surge Panels that pass data to remote analysis servers, which can receive other system or external data. The analysis servers compare measurements to predicted values and can standardize the predicted values to account for external conditions. The comparison can result in difference values used to generate probable causes and optimization recommendations. The system outputs reports or other data display using a graphical user interface that can be adjusted for an anticipated user.

Abstract: This application relates to a building energy analysis and management system for measurement and verification of building performance. The system can analyze, optimize, manage, maintain, trouble shoot, and/or modify building systems, such as HVAC systems, in connection with the building energy usage. Measurements may be gathered for one or more HVAC units coupled to pressure independent valves, and sent to one or more Surge Panels that pass data to remote analysis servers, which can receive other system or external data. The analysis servers compare measurements to predicted values and can standardize the predicted values to account for external conditions. The comparison can result in difference values used to generate probable causes and optimization recommendations. The system outputs reports or other data display using a graphical user interface that can be adjusted for an anticipated user.

Abstract: This application relates to a building energy analysis and management system for measurement and verification of building performance. The system can analyze, optimize, manage, maintain, trouble shoot, and/or modify building systems, such as HVAC systems, in connection with the building energy usage. Measurements may be gathered for one or more HVAC units coupled to pressure independent valves, and sent to one or more Surge Panels that pass data to remote analysis servers, which can receive other system or external data. The analysis servers compare measurements to predicted values and can standardize the predicted values to account for external conditions. The comparison can result in difference values used to generate probable causes and optimization recommendations. The system outputs reports or other data display using a graphical user interface that can be adjusted for an anticipated user.

Abstract: This application relates to a building energy analysis and management system for measurement and verification of building performance. The system can analyze, optimize, manage, maintain, trouble shoot, and/or modify building systems, such as HVAC systems, in connection with the building energy usage. Measurements may be gathered for one or more HVAC units coupled to pressure independent valves, and sent to one or more Surge Panels that pass data to remote analysis servers, which can receive other system or external data. The analysis servers compare measurements to predicted values and can standardize the predicted values to account for external conditions. The comparison can result in difference values used to generate probable causes and optimization recommendations. The system outputs reports or other data display using a graphical user interface that can be adjusted for an anticipated user.

Abstract: This application relates to a building energy analysis and management system for measurement and verification of building performance. The system can analyze, optimize, manage, maintain, trouble shoot, and/or modify building systems, such as HVAC systems, in connection with the building energy usage. Measurements may be gathered for one or more HVAC units coupled to pressure independent valves, and sent to one or more Surge Panels that pass data to remote analysis servers, which can receive other system or external data. The analysis servers compare measurements to predicted values and can standardize the predicted values to account for external conditions. The comparison can result in difference values used to generate probable causes and optimization recommendations. The system outputs reports or other data display using a graphical user interface that can be adjusted for an anticipated user.

Abstract: This application relates to a building energy analysis and management system for measurement and verification of building performance. The system can analyze, optimize, manage, maintain, trouble shoot, and/or modify building systems, such as HVAC systems, in connection with the building energy usage. Measurements may be gathered for one or more HVAC units coupled to pressure independent valves, and sent to one or more Surge Panels that pass data to remote analysis servers, which can receive other system or external data. The analysis servers compare measurements to predicted values and can standardize the predicted values to account for external conditions. The comparison can result in difference values used to generate probable causes and optimization recommendations. The system outputs reports or other data display using a graphical user interface that can be adjusted for an anticipated user.

Abstract: A driveshaft assembly having a tubular shaft, an end component, and an annular anti-fretting spacer is disclosed. The tubular shaft has a first receiving end portion with an opening and an inner diameter, a center portion with an inner diameter, and an interior with an inner surface. The driveshaft end component has an insert end portion and an attachment end portion. The spacer has a first outer diameter that is substantially equal to the receiving end portion inner diameter, a second outer diameter, and an outer surface. At least a portion of the outer surface contacts the shaft inner surface and the spacer is disposed on the insert end portion of the driveshaft end component and the insert end portion, including the spacer, is disposed within the receiving end portion-with an interference fit, and the shaft is rigidly coupled to the driveshaft end component.

Abstract: A driveshaft assembly having a tubular shaft, an end component, and an annular anti-fretting spacer is disclosed. The tubular shaft has a first receiving end portion with an opening and an inner diameter, a center portion with an inner diameter, and an interior with an inner surface. The driveshaft end component has an insert end portion and an attachment end portion. The spacer has a first outer diameter that is substantially equal to the receiving end portion inner diameter, a second outer diameter, and an outer surface. At least a portion of the outer surface contacts the shaft inner surface and the spacer is disposed on the insert end portion of the driveshaft end component and the insert end portion, including the spacer, is disposed within the receiving end portion with an interference fit, and the shaft is rigidly coupled to the driveshaft end component.

Abstract: A system of semi-flexible plates arranged and positioned within footwear so as to retain the flexibility associated with the footwear. The system utilizes panels comprised of hybrid carbon composite materials that have been specifically formed and cut to fit various components within the shoe. These semi-flexible panels are configured with apertures to receive placement stitching to retain the panels in a particular location within the construction of the shoe. Various layers of padding are provided to insulate the feet from the panels and from the external surfaces of the shoe. Plates and panels are uniquely positioned in the heel region and on the sides of the shoe or boot. The system provides inter-leaved rib plates extending from either side of the shoe up over the split tongue of the shoe providing flexible protection to both the sides and the top of the wearer's foot.

Abstract: A driveshaft assembly having a tubular shaft, an end component, and an annular anti-fretting spacer is disclosed. The tubular shaft has a first receiving end portion with an opening and an inner diameter, a center portion with an inner diameter, and an interior with an inner surface. The driveshaft end component has an insert end portion and an attachment end portion. The spacer has a first outer diameter that is substantially equal to the receiving end portion inner diameter, a second outer diameter, and an outer surface. At least a portion of the outer surface contacts the shaft inner surface and the spacer is disposed on the insert end portion of the driveshaft end component and the insert end portion, including the spacer, is disposed within the receiving end portion with an interference fit, and the shaft is rigidly coupled to the driveshaft end component.

Abstract: A method and apparatus for symmetric verification of a client device and a web site are described. In one embodiment, the method comprises receiving an identity verification request for an electronic transaction between a client device and a website. In one embodiment, the method may also comprise verifying an identity of both a user associated with the client device and the web site using symmetric verification, and transmitting verification results to the web site and the client device.

Abstract: An insertion set for insertion into a skin of a user. The insertion set includes an insertable substantially insoluble flexible portion and a soluble material. The insertable substantially insoluble flexible portion is capable of remaining in the skin after insertion. The soluble material is coupled to the insertable insoluble flexible portion and facilitates piercing the skin, and the soluble material dissolves in the skin of the user. Also, the soluble material holds the substantially insoluble flexible portion in a rigid state. Preferably, the insertion set is an infusion set or a sensor set. The sets may include a cannula as part of the insertable substantially insoluble portion. The cannula may be formed from a flexible material or a flexible metal tube. Preferably, the soluble material is formed from a at least one saccharide, such as a monosaccharide or a polysaccharide, a protein, a starch, other biocompatible materials, or the like.

Abstract: A mouse system (100) for authenticating a user and providing access to a computer (212) includes a pointing device and card reader (106) which share a computer interface port (222) of the computer (212). User information is read off the card (104), converted to pointing device codes, and provided to the computer (212). The computer reconverts the pointing device codes to user information to deny or grant access. The card reader (106) is capable of reading commercially available smart cards, credit cards, and other media having user information electronically stored on the card (104).

Abstract: A display system (10) collects data generated by a plurality of sensors (12) and performs an image process (24) to graphically present the sensor data on a display (16). The sensor data may be characterized by gap periods (52) during which the data are unavailable. A compress process (30) evaluates raw sensor data (26) and forms a compressed table (32) from which time-lines (56) for each sensor (12) may be drawn. A draw process (34) and a decompress process (36) draw collinear line segments (54) separated by gaps (52) for selected sensors (12). A time-line window (64) may be overlaid on the graphic image data.

Abstract: Isolation amplifier circuitry for driving inductive as well as resistive ds in an interchangeable circuit design. The device comprises a differential amplifier having both A.C. and D.C. feedback paths when used in both modes of operation with a capability of programmable gain.