Patents by Inventor Neboisa Janjic

Neboisa Janjic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity oligonucleotide ligands to growth factors
    Patent number: 6207816
    Abstract: Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGF&bgr;, PDGF and hKGF. Included in the invention are specific RNA and ssDNA ligands to TGF&bgr;1 and PDGF identified by the SELEX method. Also included in the invention are specific RNA ligands to hKGF identified by the SELEX method. Further included are RNA ligands that inhibit the interaction of TGF&bgr;1 and hKGF with their receptors and DNA ligands that inhibit the interaction of PDGF with its receptor.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: March 27, 2001
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Larry Gold, Neboisa Janjic, Nikos Pagratis