Patents by Inventor Nebojsa Nikolic
Nebojsa Nikolic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220153823Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: ApplicationFiled: January 31, 2022Publication date: May 19, 2022Inventors: Wolfgang Teschner, Harald Arno Butterwec, Azra Pljevljakovic, Theresa Friederik Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Patent number: 11242380Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: GrantFiled: November 13, 2018Date of Patent: February 8, 2022Assignee: Takeda Pharmaceutical Company LimitedInventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Publication number: 20190085064Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: ApplicationFiled: November 13, 2018Publication date: March 21, 2019Inventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Patent number: 10125189Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: GrantFiled: September 16, 2015Date of Patent: November 13, 2018Assignees: Baxalta Incorporated, Baxalta GmbHInventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Publication number: 20160244512Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: ApplicationFiled: September 16, 2015Publication date: August 25, 2016Inventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Patent number: 9175068Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: GrantFiled: July 24, 2013Date of Patent: November 3, 2015Assignees: Baxalta Incorporated, Baxalta GmbHInventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Publication number: 20140030252Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: ApplicationFiled: July 24, 2013Publication date: January 30, 2014Applicants: Baxter Healthcare S.A., Baxter International Inc.Inventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Patent number: 8546548Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: GrantFiled: May 27, 2010Date of Patent: October 1, 2013Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Patent number: 8454833Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: GrantFiled: November 16, 2011Date of Patent: June 4, 2013Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Publication number: 20120136139Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: ApplicationFiled: November 16, 2011Publication date: May 31, 2012Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Patent number: 8075782Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: GrantFiled: August 20, 2010Date of Patent: December 13, 2011Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Patent number: 8075781Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: GrantFiled: August 20, 2010Date of Patent: December 13, 2011Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Patent number: 7959809Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: GrantFiled: December 22, 2008Date of Patent: June 14, 2011Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Publication number: 20100330071Abstract: The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicants: Baxter International Inc., Baxter Healthcare S.A.Inventors: Wolfgang Teschner, Harald Arno Butterweck, Azra Pljevljakovic, Theresa Friederike Bauer, Bernhard Koelbl, Hans-Peter Schwarz, Nebojsa Nikolic, Gerhard Poelsler, Johanna Kindermann
-
Publication number: 20100317081Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: ApplicationFiled: August 20, 2010Publication date: December 16, 2010Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Publication number: 20100314317Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: ApplicationFiled: August 20, 2010Publication date: December 16, 2010Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
-
Publication number: 20090188862Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.Type: ApplicationFiled: December 22, 2008Publication date: July 30, 2009Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic