Patents by Inventor Nedim Ince

Nedim Ince has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parasitic biological agents for treatment and prevention of graft versus host disease
    Patent number: 9730988
    Abstract: The invention relates to helminthic parasite preparations and their use for treatment or prevention of GVHD in a subject that has undergone a transplant. The invention also related to helminthic parasite preparations and their use for prevention of GVHD in a subject prior to a transplant.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: August 15, 2017
    Assignee: University of Iowa Research Foundation
    Inventors: Mirac Nedim Ince, David E. Elliott, George J. Weiner
  • Parasitic Biological Agents for Treatment and Prevention of Graft Versus Host Disease
    Publication number: 20160045581
    Abstract: The invention relates to helminthic parasite preparations and their use for treatment or prevention of GVHD in a subject that has undergone a transplant. The invention also related to helminthic parasite preparations and their use for prevention of GVHD in a subject prior to a transplant.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 18, 2016
    Inventors: Mirac Nedim Ince, David E. Elliott, George J. Weiner
  • DIAGNOSIS AND TREATMENT OF MALIGNANT NEOPLASMS
    Publication number: 20100144837
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: November 25, 2009
    Publication date: June 10, 2010
    Applicant: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • DIAGNOSIS AND TREATMENT OF MALIGNANT NEOPLASMS
    Publication number: 20100136581
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: November 25, 2009
    Publication date: June 3, 2010
    Applicant: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Methods for Treating and Preventing Apoptosis-Related Diseases Using Rna Interfering Agents
    Publication number: 20070254850
    Abstract: The present invention is based, at least in part, on the discovery of compositions and methods useful in the modulation, e.g., inhibition, of gene expression or protein activity. In particular, the present invention is based on novel RNA interfering agents, e.g., siRNA molecules which target apoptosis-related genes or proinflammatory cytokines, and result in reduction, e.g., prolonged reduction, of apoptosis-related gene expression or proinflammatory cytokine expression in cells. Inhibition of apoptosis-related gene expression or protein activity or proinflammatory cytokine expression or protein activity, e.g., by the siRNAs of the invention, inhibits apoptosis-mediated diseases or disorders and proinflammatory cytokine mediated diseases or disorders, including, for example, transplant rejection, hepatitis, liver injury, sepsis, and cancer.
    Type: Application
    Filed: October 30, 2003
    Publication date: November 1, 2007
    Inventors: Judy Lieberman, Manjunath Narasimhaswamy, Erwei Song, Sang-Kyung Lee, Nedim Ince, Premlata Shankar
  • Diagnosis and treatment of malignant neoplasms
    Publication number: 20060211058
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: March 15, 2006
    Publication date: September 21, 2006
    Inventors: Jack Wands, Suzanne de la Monte, Nedim Ince, Rolf Carlson
  • Diagnosis and treatment of malignant neoplasms
    Patent number: 7094556
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: August 22, 2006
    Assignee: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Patent number: 6815415
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: November 9, 2004
    Assignee: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Patent number: 6812206
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: November 2, 2004
    Assignee: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Patent number: 6797696
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: September 28, 2004
    Assignee: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Patent number: 6783758
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: August 31, 2004
    Assignee: Rhode Island Hospital
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • DIAGNOSIS AND TREATMENT OF MALIGNANT NEOPLASMS
    Publication number: 20030031670
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: November 8, 1999
    Publication date: February 13, 2003
    Inventors: JACK R. WANDS, SUZANNE M. DE LA MONTE, NEDIM INCE, ROLF I. CARLSON
  • Diagnosis and treatment of malignant neoplasms
    Publication number: 20020146421
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: July 11, 2001
    Publication date: October 10, 2002
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Publication number: 20020122802
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: July 11, 2001
    Publication date: September 5, 2002
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Publication number: 20020114811
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: July 11, 2001
    Publication date: August 22, 2002
    Inventors: Jack R. Wands, Suzanne M. de la Mote, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms statement as to federally sponsored research
    Publication number: 20020114810
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: July 11, 2001
    Publication date: August 22, 2002
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson
  • Diagnosis and treatment of malignant neoplasms
    Publication number: 20020102263
    Abstract: The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH.
    Type: Application
    Filed: July 11, 2001
    Publication date: August 1, 2002
    Inventors: Jack R. Wands, Suzanne M. de la Monte, Nedim Ince, Rolf I. Carlson