Patents by Inventor Neelakshi GOHAIN

Neelakshi GOHAIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable immunogen based on inner domain of HIV-1 gp120 for inducing immunity against HIV
    Patent number: 10730932
    Abstract: Stable immunogens comprising portions of the inner domain (ID) of the Human Immunodeficiency Virus (HIV-1) gp120 protein are provided. These ID immunogens selectively present the gp120 C1/C2 region in its CD4-bound state within a minimal structure. These ID immunogens can be used to vaccinate subjects against infection with HIV, the causative agent of Acquired Immunodeficiency Syndrome (AIDS). The immunogens can also be used as targets in screening to identify small molecule or peptide inhibitors that block HIV-1 viral entry and attachment steps, and as probes for identifying gp120 C1/C2 region-specific antibodies.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: August 4, 2020
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Marzena Pazgier, George Lewis, William Tolbert, Neelakshi Gohain
  • STABLE IMMUNOGEN BASED ON INNER DOMAIN OF HIV-1 GP120 FOR INDUCING IMMUNITY AGAINST HIV
    Publication number: 20170283486
    Abstract: Stable immunogens comprising portions of the inner domain (ID) of the Human Immunodeficiency Virus (HIV-1) gp120 protein are provided. These ID immunogens selectively present the gp120 C1/C2 region in its CD4-bound state within a minimal structure. These ID immunogens can be used to vaccinate subjects against infection with HIV, the causative agent of Acquired Immunodeficiency Syndrome (AIDS). The immunogens can also be used as targets in screening to identify small molecule or peptide inhibitors that block HIV-1 viral entry and attachment steps, and as probes for identifying gp120 C1/C2 region-specific antibodies.
    Type: Application
    Filed: August 19, 2015
    Publication date: October 5, 2017
    Applicant: University of Maryland, Baltimore
    Inventors: Marzena PAZGIER, George LEWIS, William TOLBERT, Neelakshi GOHAIN