Abstract: A suspo-emulsion dosage form of anthelmintic drug such as Ivermectin or niclosamide with essential oils was proposed to be used for administration to the nasal cavity and lungs. The suspo-emulsion formulation is to be administered using a suitable medical device. The composition may be used to treat or prevent viral infections such as Covid-19.

Abstract: Described herein is a regulatory parser that downloads and efficiently processes regulatory documents. The regulatory documents may be from different sources and may have different formats. The regulatory parser parses all of the text in the regulatory documents and converts into a predetermined, single format for downstream applications. The text is organized and stored in a structured tree, organized into one or more hierarchies with nodes storing segments of text from a regulatory document. In some embodiments, each node in the regulatory tree may represent a segment of text. Partitioning the text of a regulatory document into segments of text may make the storage and querying of the regulatory documents more manageable. The organization and structure of the structured tree may reduce the times and resources needed for accessing and searching for a regulatory citation. The structured tree may allow a user to manipulate a regulatory document or text.

Abstract: Described herein is a machine-learning model that categorizes and classifies regulatory text and methods for operation thereof. The machine-learning model may receive raw data. The raw data may be data in a file that includes a list of text examples (e.g., leaf node citation texts). One or more datasets may be annotated. A training, validation, and test dataset may be generated. The machine-learning model is used to determine one or more predictions regarding the category and classification of input data. The training dataset is used to train the machine-learning model, the validation dataset is used to tune the hyper parameters of the model, and the test dataset is used to evaluate its performance. The prediction(s) are stored or sent to one or more downstream applications.

Abstract: An aqueous solution of vitamin B12 can be stabilized by the synergistic effect of HPMC, carrageenan and potassium acetate. This property is used to develop four formulations—1. A solution used to prepare B12 loaded capsule shell matrix, 2. vitamin B12 injectable formulation, 3. vitamin B12 nasal formulation and 4. Vitamin B12 oral solution formulation.

Abstract: The present invention provides a process of extracting the leaves of Labisia pumila with water into a free flowing powder using accelerated solvent system and drying. The invention also relates to the immunopotentiating effects of the extract against stress. The extract has effects on fatigue, hypoxia time, potentiation of swimming endurance, bod weight, weight of the thymus and spleen and levels of CD244+ NK cells, CD4+ and CD8+ T cells, expression of ThI cytokines IL-2 and IFN-gamma, corticosterone, glutathione, alanine aminotransferase and lipid peroxidation levels.

Abstract: The present invention relates to a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) in the ratio ranging between 1:7 to 7:1 (w/w), useful in hepatoprotection; and a process for the preparation of a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) useful in hepatoprotection, said process comprising steps of grounding the particles of the t-TCA and AP into fine particles, mixing the fine particles in ratio ranging between 1:7 to 7:1 (w/w), and grinding the mixture to obtain formulation, and also, a method of hepatoprotection of a subject using the synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP), said method comprising the steps of administering the formulation to the subject.

Abstract: A method and system for facilitating error free scan is disclosed herein. The system for preventing wrong scan administration to a patient comprises: an identifier associated with a patient for identifying at least one patient parameter. The patient parameter may be configured to indicate patient information such as pregnancy or the presence of metallic implants. An interrogator is provided for automatically interrogating the identifier to obtain the at least one patient parameter during one or more predefined stages when the patient is in proximity of a scanner. A controller is operatively coupled to the interrogator for generating a wrong scan signal based on the communicated information.

Abstract: A process of isolation of pure Acteoside of high hepatoprotection from plant Colerbrookea oppositifolia, said process comprising steps of drying aerial parts of the plant, grounding the dried parts into powder, percolating the powder with water or ethanol for 3-4 times to obtain an extract, filtering the extract for clearing of suspended particles to obtain supernatant, drying the supernatant at about 45 to 55° C.

Abstract: The present invention relates to a water-soluble bioactive fraction obtained from the gum resin exudate of Boswellia serrata and to a process for the preparation thereof. The present invention also relates to a process for the isolation of a water soluble bioactive fraction containing a mixture of potassium and calcium salts of polysaccharides composed of units of arabinose, galactose and D-glucuronic acid, having marked anti-inflammatory and anti-arthritic activities from the gum resin exudate of Boswellia serrata and to the use thereof in the treatment of arthritis in the form of a pharmaceutical composition containing the bioactive fraction.

Abstract: The present invention relates to a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) in the ratio ranging between 1:7 to 7:1 (w/w), useful in hepatoprotection; and a process for the preparation of a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) useful in hepatoprotection, said process comprising steps of grounding the particles of the t-TCA and AP into fine particles, mixing the fine particles in ratio ranging between 1:7 to 7:1 (w/w), and grinding the mixture to obtain formulation, and also, a method of hepatoprotection of a subject using the synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP), said method comprising the steps of administering the formulation to the subject.

Abstract: A process of isolation of pure Acteoside of high hepatoprotection from plant Colerbrookea oppositifolia, said process comprising steps of drying aerial parts of the plant, grounding the dried parts into powder, percolating the powder with water or ethanol for 3-4 times to obtain an extract, filtering the extract for clearing of suspended particles to obtain supernatant, drying the supernatant at about 45 to 55° C.

Abstract: The present invention relates to a water-soluble bioactive fraction obtained from the gum resin exudate of Boswellia serrata and to a process for the preparation thereof. The present invention also relates to a process for the isolation of a water soluble bioactive fraction containing a mixture of potassium and calcium salts of polysaccharides composed of units of arabinose, galactose and D-glucuronic acid, having marked anti-inflammatory and anti-arthritic activities from the gum resin exudate of Boswellia serrata and to the use thereof in the treatment of arthritis in the form of a pharmaceutical composition containing the bioactive fraction.